PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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3PBD	Endothiapepsin in complex with a fragment 分子名称: 1H-isoindol-3-amine, Endothiapepsin, GLYCEROL 著者 Koester, H, Heine, A, Klebe, G. 登録日 2010-10-20 公開日 2011-10-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes. J.Med.Chem., 54, 2011
2X77	Crystal Structure of Leishmania major ADP ribosylation factor-like 1. 分子名称: ADP-RIBOSYLATION FACTOR, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Fleming, J.R, Dawson, A, Hunter, W.N. 登録日 2010-02-24 公開日 2010-03-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Leishmania Major Adp Ribosylation Factor-Like 1 and a Classification of Related Gtpase Family Members in This Kinetoplastid. Mol.Biochem.Parasitol., 174, 2010
1I56	SOLUTION STRUCTURE OF CA2+-BOUND STATE OF CANINE MILK LYSOZYME 分子名称: LYSOZYME C 著者 Kobashigawa, Y, Tsuda, S, Nitta, K. 登録日 2001-02-25 公開日 2002-02-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of Ca2+-bound state of canine milk lysozyme To be Published
4DWU	Carbonmonoxy dehaloperoxidase-hemoglobin A structure at 1.44 Angstrom resolution 分子名称: CARBON MONOXIDE, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 de Serrano, V.S, Zhao, J, Franzen, S. 登録日 2012-02-26 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 A unique role for the distal histidine observed in carbonmonoxy dehaloperoxidase-hemoglobin A structures To be Published
4J61	Crystal structure of Ribonuclease A soaked in 40% Cyclopentanone: One of twelve in MSCS set 分子名称: Ribonuclease pancreatic, SULFATE ION, cyclopentanone 著者 Kearney, B.M, Dechene, M, Swartz, P.D, Mattos, C. 登録日 2013-02-11 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 DRoP: A program for analysis of water structure on protein surfaces to be published
4J66	Crystal structure of Ribonuclease A soaked in 25% Dimethyl sulfoxide: One of twelve in MSCS set 分子名称: DIMETHYL SULFOXIDE, Ribonuclease pancreatic, SULFATE ION 著者 Kearney, B.M, Dechene, M, Swartz, P.D, Mattos, C. 登録日 2013-02-11 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.039 Å) 主引用文献 DRoP: A program for analysis of water structure on protein surfaces to be published
3PCZ	Endothiapepsin in complex with benzamidine 分子名称: BENZAMIDINE, DIMETHYL SULFOXIDE, Endothiapepsin 著者 Koester, H, Heine, A, Klebe, G. 登録日 2010-10-22 公開日 2011-10-19 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Experimental and computational active site mapping as a starting point to fragment-based lead discovery. Chemmedchem, 7, 2012
4J6P	Crystal structure of calcium2+-free wild-type CD23 lectin domain (crystal form F) 分子名称: Low affinity immunoglobulin epsilon Fc receptor 著者 Dhaliwal, B, Yuan, D, Sutton, B.J. 登録日 2013-02-11 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Conformational plasticity at the IgE-binding site of the B-cell receptor CD23. Mol.Immunol., 56, 2013
4J7V	Crystal structure of cross-linked hen egg white lysozyme soaked with 5mM [Ru(benzene)Cl2]2 分子名称: Benzeneruthenium(II) chloride, CHLORIDE ION, Lysozyme C, ... 著者 Tabe, H, Abe, S, Hikage, T, Kitagawa, S, Ueno, T. 登録日 2013-02-14 公開日 2014-02-19 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Solid Artificial Metalloenzymes: Post-Engineering of Porous Protein Crystals by Organometallic Complexes To be Published
3PEL	Structure of Greyhound Hemoglobin: Origin of High Oxygen Affinity 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Bhatt, V.S, Zaldivar-Lopez, S, Harris, D.R, Couto, C.G, Wang, P.G, Palmer, A.F. 登録日 2010-10-26 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of Greyhound hemoglobin: origin of high oxygen affinity. Acta Crystallogr.,Sect.D, 67, 2011
3PEP	REVISED 2.3 ANGSTROMS STRUCTURE OF PORCINE PEPSIN. EVIDENCE FOR A FLEXIBLE SUBDOMAIN 分子名称: ETHANOL, PEPSIN 著者 Abad-Zapatero, C, Erickson, J.W. 登録日 1989-10-24 公開日 1990-04-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Revised 2.3 A structure of porcine pepsin: evidence for a flexible subdomain Proteins, 8, 1990
4JJD	Crystal structure of the N114A Abl-SH3 domain mutant at pH4 分子名称: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Abl-SH3 domain at pH5 To be Published
3PBZ	Endothiapepsin in complex with a fragment 分子名称: 4-(diethylamino)benzohydrazide, DIMETHYL SULFOXIDE, Endothiapepsin, ... 著者 Koester, H, Heine, A, Klebe, G. 登録日 2010-10-21 公開日 2011-10-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes. J.Med.Chem., 54, 2011
2WY1	Crystal structure of rat angiotensinogen in P321 space group 分子名称: ANGIOTENSINOGEN 著者 Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. 登録日 2009-11-11 公開日 2010-10-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
2WJO	human Bace (beta secretase) in complex with Cyclohexanecarboxylic acid (2-(2-am ino-6-phenoxy-4H-quinazolin-3-yl)-2 -cyclohexyl-ethyl)- amide 分子名称: 2-AMINO-3-{(1R)-1-CYCLOHEXYL-2-[(CYCLOHEXYLCARBONYL)AMINO]ETHYL}-6-PHENOXYQUINAZOLIN-3-IUM, BETA-SECRETASE 1 著者 Mathieu, M, Dupuy, A.S. 登録日 2009-05-28 公開日 2010-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Shape and Medicinal Chemistry: A Perspective. J.Med.Chem., 53, 2010
3O89	Crystal Structure of Sperm Whale Myoglobin G65T 分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Huang, X, Lovelace, L, Lebioda, L. 登録日 2010-08-02 公開日 2011-12-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Investigations of Structural Factors that Influence the Mechanism of Halophenol Dehalogenation using 'Peroxidase-Like' Myoglobin mutants and 'Myoglobin-Like' Amphitrite ornata Dehaloperoxidase Mutants TO BE PUBLISHED
7Y1G	Crystal structure of human PRKACA complexed with DS01080522 分子名称: 1-chloranyl-~{N}-[(~{S})-(3-chloranyl-4-cyano-phenyl)-[(2~{R},4~{S})-4-oxidanylpyrrolidin-2-yl]methyl]-7-methoxy-isoquinoline-6-carboxamide, ZINC ION, cAMP-dependent protein kinase catalytic subunit alpha 著者 Suzuki, M, Ubukata, O, Toyoda, A. 登録日 2022-06-08 公開日 2022-09-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Novel protein kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor shows anti-tumor activity in a fibrolamellar hepatocellular carcinoma model. Biochem.Biophys.Res.Commun., 621, 2022
4JN4	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-14 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
3O9H	Crystal Structure of wild-type HIV-1 Protease in complex with kd26 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-3-[(1,3-benzodioxol-5-ylsulfonyl)(2-ethylbutyl)amino]-1-benzyl-2-hydroxypropyl}carbamate, ACETATE ION, PHOSPHATE ION, ... 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2010-08-04 公開日 2011-08-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem.Biol., 20, 2013
7Y6M	Intracellular Subtilisin from Bacillus sp. 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Intracellular serine protease 著者 Hussin, N, Jamaluddin, H, Jonet, M.A. 登録日 2022-06-21 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Intracellular Subtilisin from Bacillus sp. TO BE PUBLISHED
4BEL	BACE2 XAPERONE COMPLEX 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-SECRETASE 2, CHLORIDE ION, ... 著者 Banner, D.W, Kuglstatter, A, Benz, J, Stihle, M, Ruf, A. 登録日 2013-03-11 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69, 2013
2WXW	Crystal structure of human angiotensinogen 分子名称: ANGIOTENSINOGEN 著者 Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. 登録日 2009-11-11 公開日 2010-10-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
2WTG	High resolution 3D structure of C.elegans globin-like protein GLB-1 分子名称: GLOBIN-LIKE PROTEIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE 著者 Geuens, E, Hoogewijs, D, Nardini, M, Vinck, E, Pesce, A, Kiger, L, Fago, A, Tilleman, L, De Henau, S, Marden, M, Weber, R.E, Van Doorslaer, S, Vanfleteren, J, Moens, L, Bolognesi, M, Dewilde, S. 登録日 2009-09-16 公開日 2010-04-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Globin-Like Proteins in Caenorhabditis Elegans: In Vivo Localization, Ligand Binding and Structural Properties. Bmc Biochem., 11, 2010
4DI2	Crystal structure of BACE1 in complex with hydroxyethylamine inhibitor 37 分子名称: (2R)-N-{(2S,3R)-4-{[(4'S)-6'-(2,2-dimethylpropyl)-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl]amino}-3-hydroxy-1-[3-(1,3-thiazol-2-yl)phenyl]butan-2-yl}-2-methoxypropanamide, Beta-secretase 1, GLYCEROL 著者 Whittington, D.A, Long, A.M. 登録日 2012-01-30 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and synthesis of potent, orally efficacious hydroxyethylamine derived beta-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. J.Med.Chem., 55, 2012
2X1A	Structure of Rna15 RRM with RNA bound (G) 分子名称: 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15 著者 Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. 登録日 2010-01-06 公開日 2010-02-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors. Nucleic Acids Res., 38, 2010

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