8XBU
 
 | | The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding | | 分子名称: | DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... | | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-12-07 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
|
|
9CF3
 | | Parasitella parasitica Fanzor (PpFz) State 4 | | 分子名称: | DNA non-target strand, DNA target strand, MAGNESIUM ION, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
|
|
9CF0
 | | Parasitella parasitica Fanzor (PpFz) State 1 | | 分子名称: | DNA non-target strand, DNA target strand, Maltose/maltodextrin-binding periplasmic protein,Parasitella parasitica Fanzor 1, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
|
|
7VEH
 | | Type I-F Anti-CRISPR protein AcrIF13 | | 分子名称: | AcrIF13 | | 著者 | Gao, T, Feng, Y. | | 登録日 | 2021-09-08 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Mechanistic insights into the inhibition of the CRISPR-Cas surveillance complex by anti-CRISPR protein AcrIF13.
J.Biol.Chem., 298, 2022
|
|
8XKE
 | | The structure of HLA-A/14-3-D | | 分子名称: | Beta-2-microglobulin, GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR, HLA class I heavy chain | | 著者 | Zhang, J.N, Yue, C, Liu, J, Sun, Z.Y. | | 登録日 | 2023-12-23 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
|
|
8XFZ
 | | The structure of HLA-A/L1-2 | | 分子名称: | Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1 | | 著者 | Zhang, J.N, Yue, C, Liu, J. | | 登録日 | 2023-12-14 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
|
|
8XKC
 | | The structure of HLA-A/Pep16 | | 分子名称: | Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1 | | 著者 | Zhang, J.N, Yue, C, Liu, J. | | 登録日 | 2023-12-23 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
|
|
8F19
 | | Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) | | 分子名称: | GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-5, ... | | 著者 | Jiou, J, Chook, Y.M. | | 登録日 | 2022-11-04 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8F1E
 | |
8F0X
 | | Cryo-EM structure of Kap114 bound to H2A-H2B | | 分子名称: | Histone H2A.2, Histone H2B.2, Importin subunit beta-5 | | 著者 | Jiou, J, Chook, Y.M. | | 登録日 | 2022-11-04 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
4GJ9
 | | Crystal structure of renin in complex with GP055321 (compound 4) | | 分子名称: | (2R)-1-(3,8-dihydrodibenzo[b,f]pyrrolo[3,4-d]azepin-2(1H)-yl)propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | | 著者 | Ostermann, N, Zink, F, Kroemer, M. | | 登録日 | 2012-08-09 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore.
J.Med.Chem., 56, 2013
|
|
4GJA
 | | Crystal structure of renin in complex with NVP-AYL747 (compound 5) | | 分子名称: | (3S,5R)-N-(2,2-diphenylethyl)-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... | | 著者 | Ostermann, N, Zink, F, Kroemer, M. | | 登録日 | 2012-08-09 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore.
J.Med.Chem., 56, 2013
|
|
4GJC
 | | Crystal structure of renin in complex with NVP-BCH965 (compound 9) | | 分子名称: | (3S,5R)-5-{[(4-methylphenyl)sulfonyl]amino}-N-(9H-xanthen-9-ylmethyl)piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... | | 著者 | Ostermann, N, Zink, F, Kroemer, M. | | 登録日 | 2012-08-09 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore.
J.Med.Chem., 56, 2013
|
|
1D7K
 | | CRYSTAL STRUCTURE OF HUMAN ORNITHINE DECARBOXYLASE AT 2.1 ANGSTROMS RESOLUTION | | 分子名称: | HUMAN ORNITHINE DECARBOXYLASE | | 著者 | Almrud, J.J, Oliveira, M.A, Kern, A.D, Grishin, N.V, Phillips, M.A, Hackert, M.L. | | 登録日 | 1999-10-18 | | 公開日 | 2000-10-25 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding.
J.Mol.Biol., 295, 2000
|
|
7OHQ
 | |
7OHP
 | |
7OHS
 | |
7OHW
 | |
7OHV
 | |
7OHX
 | |
7OHR
 | |
7VS4
 | | Crystal structure of PacII_M1M2S-DNA(m6A)-SAH complex | | 分子名称: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | | 著者 | Zhu, J, Gao, P. | | 登録日 | 2021-10-25 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems.
Nat Commun, 13, 2022
|
|
7VRU
 | | Crystal structure of PacII_M1M2S-DNA-SAH complex | | 分子名称: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | | 著者 | Zhu, J, Gao, P. | | 登録日 | 2021-10-25 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems.
Nat Commun, 13, 2022
|
|
7OC7
 | | LasB, alpha-alkyl-N-aryl mercaptoacetamide | | 分子名称: | (2R)-N,3-diphenyl-2-sulfanyl-propanamide, CALCIUM ION, Neutral metalloproteinase, ... | | 著者 | Koehnke, J, Sikandar, A. | | 登録日 | 2021-04-26 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
2ZTM
 | | T190S mutant of D-3-hydroxybutyrate dehydrogenase | | 分子名称: | (3S)-3-HYDROXYBUTANOIC ACID, D(-)-3-hydroxybutyrate dehydrogenase, MAGNESIUM ION, ... | | 著者 | Nakashima, K, Nakajima, Y, Ito, K, Yoshimoto, T. | | 登録日 | 2008-10-07 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.
J.Biochem., 145, 2009
|
|
