7OC7

LasB, alpha-alkyl-N-aryl mercaptoacetamide

Summary for 7OC7

Entry DOI	10.2210/pdb7oc7/pdb
Descriptor	Neutral metalloproteinase, ZINC ION, (2R)-N,3-diphenyl-2-sulfanyl-propanamide, ... (5 entities in total)
Functional Keywords	lasb, alpha-alkyl-n-aryl mercaptoacetamide, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	33422.16
Authors	Koehnke, J.,Sikandar, A. (deposition date: 2021-04-26, release date: 2022-01-19, Last modification date: 2024-01-31)
Primary citation	Kaya, C.,Walter, I.,Yahiaoui, S.,Sikandar, A.,Alhayek, A.,Konstantinovic, J.,Kany, A.M.,Haupenthal, J.,Kohnke, J.,Hartmann, R.W.,Hirsch, A.K.H. Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors. Angew.Chem.Int.Ed.Engl., 61:e202112295-e202112295, 2022 Cited by PubMed: 34762767 DOI: 10.1002/anie.202112295 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation