7DVL
 
 | | Crystal Structure of the Catalytic Domain of Botulinum Neurotoxin Subtype A3 | | 分子名称: | Bont/A3, ZINC ION | | 著者 | Wu, Y, Leka, O, Kammerer, R, Li, X. | | 登録日 | 2021-01-13 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Crystal structure of the catalytic domain of botulinum neurotoxin subtype A3.
J.Biol.Chem., 296, 2021
|
|
6QFX
 | | Human carbonic anhydrase II with bound IrCp* complex (cofactor 10) to generate an artificial transfer hydrogenase (ATHase) | | 分子名称: | 2-(9-chloranyl-2',3',4',5',6'-pentamethyl-4-oxidanyl-7-oxidanylidene-spiro[1$l^{4},8-diaza-9$l^{8}-iridabicyclo[4.3.0]nona-1,3,5-triene-9,1'-1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane]-8-yl)-~{N}-(4-sulfamoylphenyl)ethanamide, Carbonic anhydrase 2, SULFATE ION, ... | | 著者 | Rebelein, J.G. | | 登録日 | 2019-01-10 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein.
Acs Catalysis, 9, 2019
|
|
7ELC
 | | Structure of monomeric complex of MACV L bound to Z and 3'-vRNA | | 分子名称: | 3'-vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
|
|
7ELA
 | | Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A) | | 分子名称: | 3-'vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
|
|
8BTD
 | | Giardia Ribosome in PRE-T Hybrid State (D1) | | 分子名称: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | | 著者 | Majumdar, S, Emmerich, A.G, Sanyal, S. | | 登録日 | 2022-11-28 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
|
|
8BR8
 | | Giardia ribosome in POST-T state (A1) | | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | 著者 | Majumdar, S, Emmerich, A.G, Sanyal, S. | | 登録日 | 2022-11-22 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
|
|
8BRM
 | | Giardia ribosome in POST-T state, no E-site tRNA (A6) | | 分子名称: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | | 著者 | Majumdar, S, Emmerich, A.G, Sanyal, S. | | 登録日 | 2022-11-23 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
|
|
8BSI
 | | Giardia ribosome chimeric hybrid-like GDP+Pi bound state (B1) | | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | 著者 | Majumdar, S, Emmerich, A.G, Sanyal, S. | | 登録日 | 2022-11-25 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
|
|
7EL9
 | | Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex) | | 分子名称: | MANGANESE (II) ION, Machupo virus 3'-vRNA promoter, RING finger protein Z, ... | | 著者 | Peng, R, Xu, X, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
|
|
8BTR
 | | Giardia Ribosome in PRE-T Hybrid State (D2) | | 分子名称: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | | 著者 | Majumdar, S, Emmerich, A.G, Sanyal, S. | | 登録日 | 2022-11-29 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
|
|
7ELB
 | | Structure of Machupo virus L polymerase in complex with Z protein (dimeric form) | | 分子名称: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | | 著者 | Peng, R, Xu, X, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
|
|
7EGK
 | | Bicarbonate transporter complex SbtA-SbtB bound to AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Membrane-associated protein SbtB, SODIUM ION, ... | | 著者 | Fang, S, Huang, X, Zhang, X, Zhang, P. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-06-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7EGL
 | | Bicarbonate transporter complex SbtA-SbtB bound to HCO3- | | 分子名称: | BICARBONATE ION, Membrane-associated protein SbtB, SODIUM ION, ... | | 著者 | Fang, S, Huang, X, Zhang, X, Zhang, P. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8PHJ
 | | cA4-bound Cami1 in complex with 70S ribosome | | 分子名称: | 16S rRNA, 23S rRNA (2862-MER), 5S rRNA, ... | | 著者 | Tamulaitiene, G, Mogila, I, Sasnauskas, G, Tamulaitis, G. | | 登録日 | 2023-06-20 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling.
Science, 382, 2023
|
|
6QKN
 | | Structure of the azide-inhibited form of cytochrome c peroxidase from obligate human pathogenic bacterium Neisseria gonorrhoeae | | 分子名称: | AZIDE ION, CALCIUM ION, Cytochrome-c peroxidase, ... | | 著者 | Carvalho, A.L, Romao, M.J, Pauleta, S, Nobrega, C. | | 登録日 | 2019-01-29 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the mixed-valence, active form, of cytochrome c peroxidase from obligate human pathogenic bacterium Neisseria gonorrhoeae
To Be Published
|
|
7HVP
 | | X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR | | 分子名称: | HIV-1 PROTEASE, INHIBITOR ACE-SER-LEU-ASN-PHE-PSI(CH(OH)-CH2N)-PRO-ILE VME (JG-365) | | 著者 | Swain, A.L, Miller, M.M, Green, J, Rich, D.H, Schneider, J, Kent, S.B.H, Wlodawer, A. | | 登録日 | 1990-09-13 | | 公開日 | 1993-07-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.
Proc.Natl.Acad.Sci.USA, 87, 1990
|
|
7JGA
 | | Cryo-EM structure of bedaquiline-saturated Mycobacterium smegmatis ATP synthase rotational state 3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | 著者 | Guo, H, Courbon, G.M, Rubinstein, J.L. | | 登録日 | 2020-07-18 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
Nature, 589, 2021
|
|
6Q1L
 | | Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and 3-iodo-L-tyrosine | | 分子名称: | 3-IODO-TYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Sun, Z, Kavran, J.M, Rokita, S.E. | | 登録日 | 2019-08-05 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana.
J.Biol.Chem., 297, 2021
|
|
6QFA
 | | CryoEM structure of a beta3K279T GABA(A)R homomer in complex with histamine and megabody Mb25 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit beta-3, HISTAMINE, ... | | 著者 | Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkoening, A, Zoegg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J. | | 登録日 | 2019-01-09 | | 公開日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | | 主引用文献 | Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
|
|
7JJI
 | | Structure of SARS-CoV-2 3Q-2P full-length prefusion spike trimer (C3 symmetry) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxyethyl 2-deoxy-3,5-bis-O-(2-hydroxyethyl)-6-O-(2-{[(9E)-octadec-9-enoyl]oxy}ethyl)-alpha-L-xylo-hexofuranoside, ... | | 著者 | Bangaru, S, Turner, H.L, Ozorowski, G, Antanasijevic, A, Ward, A.B. | | 登録日 | 2020-07-26 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate.
Science, 370, 2020
|
|
7GSP
 | | RIBONUCLEASE T1/2',3'-CGPS, NON-PRODUCTIVE | | 分子名称: | GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, PHOSPHATE ION, RIBONUCLEASE T1 | | 著者 | Zegers, I, Wyns, L. | | 登録日 | 1997-12-10 | | 公開日 | 1998-03-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
|
|
8GCR
 | | HPV16 E6-E6AP-p53 complex | | 分子名称: | Cellular tumor antigen p53, Maltose/maltodextrin-binding periplasmic protein,Protein E6, Ubiquitin-protein ligase E3A, ... | | 著者 | Bratkowski, M.A, Wang, J.C.K, Hao, Q, Nile, A.H. | | 登録日 | 2023-03-02 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structure of the p53 degradation complex from HPV16.
Nat Commun, 15, 2024
|
|
7JFO
 | | EPYC1(49-72)-bound Rubisco | | 分子名称: | LCI5, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, ... | | 著者 | Matthies, D, Jonikas, M.C, He, S. | | 登録日 | 2020-07-17 | | 公開日 | 2020-11-18 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.13 Å) | | 主引用文献 | The structural basis of Rubisco phase separation in the pyrenoid.
Nat.Plants, 6, 2020
|
|
7JG6
 | | Cryo-EM structure of bedaquiline-free Mycobacterium smegmatis ATP synthase rotational state 2 (backbone model) | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | 著者 | Guo, H, Courbon, G.M, Rubinstein, J.L. | | 登録日 | 2020-07-18 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
Nature, 589, 2021
|
|
7JJC
 | |
