3TRT
 
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3TS0
 | | Mouse Lin28A in complex with let-7f-1 microRNA pre-element | | 分子名称: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*AP*GP*UP*GP*AP*UP*UP*UP*UP*AP*CP*CP*CP*UP*GP*GP*AP*G)-3'), ZINC ION | | 著者 | Nam, Y, Sliz, P. | | 登録日 | 2011-09-11 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.763 Å) | | 主引用文献 | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Cell(Cambridge,Mass.), 147, 2011
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3TSI
 | | Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain | | 分子名称: | Hemagglutinin-neuraminidase | | 著者 | Bose, S, Welch, B.D, Kors, C.A, Yuan, P, Jardetzky, T.S, Lamb, R.A. | | 登録日 | 2011-09-13 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | | 主引用文献 | Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion.
J.Virol., 85, 2011
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3TTV
 | | Structure of the F413E variant of E. coli KatE | | 分子名称: | Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Loewen, P.C, Jha, V. | | 登録日 | 2011-09-15 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Mutation of Phe413 to Tyr in catalase KatE from Escherichia coli leads to side chain damage and main chain cleavage.
Arch.Biochem.Biophys., 525, 2012
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3TUJ
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3U4W
 | | Src in complex with DNA-templated macrocyclic inhibitor MC4b | | 分子名称: | GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... | | 著者 | Seeliger, M.A, Liu, D.R, Georghiou, G, Kleiner, R.E, Pulkoski-Gross, M. | | 登録日 | 2011-10-10 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles.
Nat.Chem.Biol., 8, 2012
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3U62
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3TXX
 | | Crystal structure of putrescine transcarbamylase from Enterococcus faecalis | | 分子名称: | Putrescine carbamoyltransferase, SULFATE ION | | 著者 | Shi, D, Yu, X, Zhao, G, Allewell, N.M, Tuchman, M. | | 登録日 | 2011-09-23 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of putrescine transcarbamylase from Enterococcus faecalis: Structural insights into the oligomeric assembly and the active site
To be Published
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3U01
 | | Crystal structure of onconase double mutant C30A/C75A at 1.12 A resolution | | 分子名称: | ACETATE ION, Protein P-30, SULFATE ION | | 著者 | Kurpiewska, K, Torrent, G, Ribo, M, Vilanova, M, Loch, J, Lewinski, K. | | 登録日 | 2011-09-28 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution.
Biopolymers, 101, 2014
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3U0H
 | | The Structure of a Xylose Isomerase domain protein from Alicyclobacillus acidocaldarius subsp. acidocaldarius. | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Cuff, M.E, Chhor, G, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-09-28 | | 公開日 | 2011-11-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Structure of a Xylose Isomerase domain protein from Alicyclobacillus acidocaldarius subsp. acidocaldarius.
TO BE PUBLISHED
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3U8I
 | | Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism | | 分子名称: | CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... | | 著者 | Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F. | | 登録日 | 2011-10-17 | | 公開日 | 2012-10-17 | | 最終更新日 | 2013-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
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3U24
 | | The structure of a putative lipoprotein of unknown function from Shewanella oneidensis. | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | | 著者 | Cuff, M.E, Hatzos-Skintges, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-09-30 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The structure of a putative lipoprotein of unknown function from Shewanella oneidensis.
TO BE PUBLISHED
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3U96
 | | Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS | | 分子名称: | N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM, SULFATE ION, Tyrosine-protein phosphatase yopH | | 著者 | Ho, M.C, Ke, S. | | 登録日 | 2011-10-17 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Investigation of catalytic loop structure, dynamics, and function relationship of Yersinia protein tyrosine phosphatase by temperature-jump relaxation spectroscopy and X-ray structural determination.
J.Phys.Chem.B, 116, 2012
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3U3U
 | | Crystal structure of the tablysin-15-leukotriene E4 complex | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, CITRIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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3U50
 | | Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C | | 分子名称: | Telomerase-associated protein 82, ZINC ION | | 著者 | Zeng, Z, Huang, J, Yang, Y, Lei, M. | | 登録日 | 2011-10-10 | | 公開日 | 2011-12-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3U6V
 | | Crystal Structure Analysis of L23A mutant of human GST A1-1 | | 分子名称: | Glutathione S-transferase A1 | | 著者 | Fanucchi, S, Achilonu, I.A, Khoza, T.N, Fernandes, M.A, Gildenhuys, S, Dirr, H.W. | | 登録日 | 2011-10-13 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure Analysis of L23A mutant of human GST A1-1
To be Published
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3TNB
 | | Crystal structure of GkaP mutant G209D/R230H from Geobacillus kaustophilus HTA426 | | 分子名称: | COBALT (II) ION, Phosphotriesterase | | 著者 | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | | 登録日 | 2011-09-01 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides
to be published
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3U7Z
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3TP8
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | | 登録日 | 2011-09-07 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E at cryogenic temperature
To be Published
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3UB9
 | | Periplasmic portion of the Helicobacter pylori chemoreceptor TlpB with hydroxyurea bound | | 分子名称: | GLYCEROL, N-HYDROXYUREA, SULFATE ION, ... | | 著者 | Henderson, J.N, Sweeney, E.G, Goers, J, Wreden, C, Hicks, K.G, Parthasarathy, R, Guillemin, K.J, Remington, S.J. | | 登録日 | 2011-10-23 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Structure and proposed mechanism for the pH-sensing Helicobacter pylori chemoreceptor TlpB.
Structure, 20, 2012
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3UBM
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3TQ4
 | | Crystal structure of M-PMV dUTPase with a mixed population of substrate (dUPNPP) and post-inversion product (dUMP) in the active sites | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Barabas, O, Nemeth, V, Vertessy, B.G. | | 登録日 | 2011-09-09 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion
to be published
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3TQV
 | | Structure of the nicotinate-nucleotide pyrophosphorylase from Francisella tularensis. | | 分子名称: | Nicotinate-nucleotide pyrophosphorylase, PHOSPHATE ION | | 著者 | Rudolph, M, Cheung, J, Franklin, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2011-09-09 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.
Plos One, 8, 2013
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3TRG
 | | Structure of an acylphosphatase from Coxiella burnetii | | 分子名称: | 1,2-ETHANEDIOL, Acylphosphatase, CHLORIDE ION | | 著者 | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2011-09-09 | | 公開日 | 2011-10-19 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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3TL5
 | | Discovery of GDC-0980: a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor for the Treatment of Cancer | | 分子名称: | (2S)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin-1-yl)-2-hydroxypropan-1-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | | 著者 | Murray, J.M, Wiesmann, C. | | 登録日 | 2011-08-29 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.788 Å) | | 主引用文献 | Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer.
J.Med.Chem., 54, 2011
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