PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

---

4H5W	HSC70 NBD with betaine 分子名称: ACETATE ION, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... 著者 Stec, B. 登録日 2012-09-19 公開日 2014-03-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
3MVV	Crystal structure of Staphylococcal nuclease variant Delta+PHS F34A at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. 登録日 2010-05-04 公開日 2011-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Cavities determine the pressure unfolding of proteins. Proc.Natl.Acad.Sci.USA, 109, 2012
4H5T	HSC70 NBD with ADP and Mg 分子名称: ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
7ZWV	Crystal structure of human BCL6 BTB domain in complex with compound 17 分子名称: 1,2-ETHANEDIOL, 1,3-dimethyl-5-[[6-(phenylmethylsulfanyl)pyrimidin-4-yl]amino]benzimidazol-2-one, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7VHV	Crystal structure of S. aureus D-alanine alanyl carrier protein ligase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, D-alanine--D-alanyl carrier protein ligase, MAGNESIUM ION 著者 Lee, B.J, Lee, I.-G, Im, H.G, Yoon, H.J. 登録日 2021-09-23 公開日 2022-04-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and functional analysis of the D-alanyl carrier protein ligase DltA from Staphylococcus aureus Mu50. Acta Crystallogr D Struct Biol, 78, 2022
7ZWQ	Crystal structure of human BCL6 BTB domain in complex with compound 10 分子名称: 1,2-ETHANEDIOL, B-cell lymphoma 6 protein, DIMETHYL SULFOXIDE, ... 著者 Rodrigues, M.J, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWY	Crystal structure of human BCL6 BTB domain in complex with compound 21 分子名称: 1,2-ETHANEDIOL, 2-chloranyl-4-[(phenylmethyl)amino]pyridine-3-carbonitrile, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Shetty, K, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWN	Crystal structure of human BCL6 BTB domain in complex with a WVIP peptide 分子名称: 1,2-ETHANEDIOL, ALA-TRP-VAL-ILE-PRO-ALA, B-cell lymphoma 6 protein, ... 著者 Shetty, K, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWP	Crystal structure of human BCL6 BTB domain in complex with compound 7 分子名称: 1,2-ETHANEDIOL, ALA-TRP-VAL-ILE-PRO-ALA, B-cell lymphoma 6 protein, ... 著者 Shetty, K, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWT	Crystal structure of human BCL6 BTB domain in complex with compound 14 分子名称: 1,2-ETHANEDIOL, 2-[(2-chlorophenyl)amino]-~{N}-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide, B-cell lymphoma 6 protein, ... 著者 Gunnell, E.A, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWZ	Crystal structure of human BCL6 BTB domain in complex with compound 22 分子名称: 1,2-ETHANEDIOL, ALA-TRP-VAL-ILE-PRO-ALA, B-cell lymphoma 6 protein, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWO	Crystal structure of human BCL6 BTB domain in complex with compound 2 分子名称: (5~{S},7~{R})-5-(4-chlorophenyl)-7-(2,3,4-trimethoxyphenyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine, 1,2-ETHANEDIOL, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
4H5V	HSC70 NBD with Mg 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
6WTG	SdeA DUB Domain in complex with Ubiquitin 分子名称: Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA 著者 Kenny, S, Sheedlo, M, Das, C. 登録日 2020-05-02 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA. Biochemistry, 60, 2021
7ZWS	Crystal structure of human BCL6 BTB domain in complex with compound 13 分子名称: 1,2-ETHANEDIOL, 2-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-2-phenyl-ethanoic acid, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWW	Crystal structure of human BCL6 BTB domain in complex with compound 18 分子名称: 1,2-ETHANEDIOL, 1,3-dimethyl-5-[(6-morpholin-4-ylpyrimidin-4-yl)amino]benzimidazol-2-one, B-cell lymphoma 6 protein 著者 Rodrigues, M.J, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWR	Crystal structure of human BCL6 BTB domain in complex with compound 11 分子名称: 1,2-ETHANEDIOL, 2-[2-[[(6~{S})-3-cyano-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl]ethanoylamino]ethanoic acid, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWX	Crystal structure of human BCL6 BTB domain in complex with compound 19 分子名称: 1,2-ETHANEDIOL, 6-[1,3-benzodioxol-5-ylmethyl(methyl)amino]-1-~{tert}-butyl-5~{H}-pyrazolo[3,4-d]pyrimidin-4-one, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
7ZWU	Crystal structure of human BCL6 BTB domain in complex with compound 15 分子名称: 1,2-ETHANEDIOL, ALA-TRP-VAL-ILE-PRO-ALA, B-cell lymphoma 6 protein, ... 著者 Collie, G.W, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2022-05-19 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays. Sci Rep, 12, 2022
4DW4	Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-UMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... 著者 Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. 登録日 2012-02-24 公開日 2012-05-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
4DWC	Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with Zn ions 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. 登録日 2012-02-24 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
4DK2	Crystal Structure of Open Trypanosoma brucei dUTPase 分子名称: Deoxyuridine triphosphatase 著者 Hemsworth, G.R, Gonzalez-Pacanowska, D, Wilson, K.S. 登録日 2012-02-03 公開日 2013-08-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 On the catalytic mechanism of dimeric dUTPases. Biochem.J., 456, 2013
4DL8	Crystal structure of Trypanosoma brucei dUTPase with dUMP, planar [AlF3-OPO3] transition state analogue, Mg2+, and Na+ 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ALUMINUM FLUORIDE, Deoxyuridine triphosphatase, ... 著者 Hemsworth, G.R, Gonzalez-Pacanowska, D, Wilson, K.S. 登録日 2012-02-06 公開日 2013-08-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 On the catalytic mechanism of dimeric dUTPases. Biochem.J., 456, 2013
3OXA	Crystal Structure of Ketosteroid Isomerase D40N/C69S/C81S/C97S/M116C-CN from P. putida 分子名称: Steroid Delta-isomerase 著者 Sigala, P.A, Fenn, T.D, Herschlag, D. 登録日 2010-09-21 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Quantitative, directional measurement of electric field heterogeneity in the active site of ketosteroid isomerase. Proc.Natl.Acad.Sci.USA, 109, 2012
4DSO	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012

<613614615616617618619620621622623624625626627628>