PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

---

5DUI	Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter 分子名称: DNA (5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'), Forkhead box protein O1 著者 Singh, P, Endrizzi, J.A, Chi, Y.-I. 登録日 2015-09-18 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.306 Å) 主引用文献 Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter. J. Struct. Biol., 198, 2017
3I73	Structural characterization for the nucleotide binding ability of subunit A with ADP of the A1AO ATP synthase 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, A-TYPE ATP SYNTHASE CATALYTIC SUBUNIT A, ... 著者 Manimekalai, S.M.S, Kumar, A, Balakrishna, A.M, Gruber, G. 登録日 2009-07-08 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution. J.Mol.Biol., 396, 2010
6ZXA	LH2 complex from Marichromatium purpuratum 分子名称: 9-cis-okenone, BACTERIOCHLOROPHYLL A, LHC domain-containing protein, ... 著者 Gardiner, A.T, Naydenova, K, Castro-Hartmann, P, Nguyen-Phan, T.C, Russo, C.J, Sader, K, Hunter, C.N, Cogdell, R.J, Qian, P. 登録日 2020-07-29 公開日 2021-02-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.38 Å) 主引用文献 The 2.4 angstrom cryo-EM structure of a heptameric light-harvesting 2 complex reveals two carotenoid energy transfer pathways. Sci Adv, 7, 2021
3I72	Structural characterization for the nucleotide binding ability of subunit A with SO4 of the A1AO ATP synthase 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, A-TYPE ATP SYNTHASE CATALYTIC SUBUNIT A, ... 著者 Manimekalai, S.M.S, Kumar, A, Balakrishna, A.M, Gruber, G. 登録日 2009-07-07 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution. J.Mol.Biol., 396, 2010
5F5F	X-ray structure of Roquin ROQ domain in complex with a Selex-derived hexa-loop RNA motif 分子名称: RNA (5'-R(P*UP*GP*AP*CP*UP*GP*CP*GP*UP*UP*UP*UP*AP*GP*GP*AP*GP*UP*UP*A)-3'), Roquin-1 著者 Janowski, R, Schlundt, A, Sattler, M, Niessing, D. 登録日 2015-12-04 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40. Nat Commun, 7, 2016
6EHG	complement component C3b in complex with a nanobody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Jensen, R.K, Andersen, K.R, Gadeberg, T.A.F, Laursen, N.S, Andersen, G.R. 登録日 2017-09-13 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. J. Biol. Chem., 293, 2018
1OZ8	Intramolecular higher-order packing of parallel quadruplexes comprising a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad of GGA triplet repeat DNA 分子名称: 5'-D(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3' 著者 Matsugami, A, Okuizumi, T, Uesugi, S, Katahira, M. 登録日 2003-04-08 公開日 2004-04-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Intramolecular Higher Order Packing of Parallel Quadruplexes Comprising a G:G:G:G Tetrad and a G(:A):G(:A):G(:A):G Heptad of GGA Triplet Repeat DNA J.BIOL.CHEM., 278, 2003
4XHE	Crystal Structure of A-AChBP in complex with pinnatoxin A 分子名称: CALCIUM ION, CHLORIDE ION, Pinnatoxin A, ... 著者 Bourne, Y, Sulzenbacher, G, Marchot, P. 登録日 2015-01-05 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs. Structure, 23, 2015
7B3A	Crystal structure of PamZ 分子名称: ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ... 著者 Loll, B, Dang, T, Mainz, A, Suessmuth, R, Wahl, M.C. 登録日 2020-11-30 公開日 2021-11-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Molecular basis of antibiotic self-resistance in a bee larvae pathogen. Nat Commun, 13, 2022
5TL4	Crystal structure of Sphingomonas paucimobilis aryl O-demethylase LigM 分子名称: AMMONIUM ION, CHLORIDE ION, GLYCEROL, ... 著者 Kohler, A.C, Adams, P.D, Simmons, B.A, Sale, K.L. 登録日 2016-10-10 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Structure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TJ5	Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase 分子名称: V-type proton ATPase subunit a, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ... 著者 Mazhab-Jafari, M.T, Rohou, A, Schmidt, C, Bueler, S.A, Benlekbir, S, Robinson, C.V, Rubinstein, J.L. 登録日 2016-10-03 公開日 2016-10-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase. Nature, 539, 2016
7FDW	Crystal structure of pepsin cleaved lactoferrin C-lobe at 2.28 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... 著者 Singh, P.K, Singh, J, Maurya, A, Sharma, P, Sharma, S, Singh, T.P. 登録日 2021-07-18 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.277 Å) 主引用文献 A Peptide Bond from the Inter-lobe Segment in the Bilobal Lactoferrin Acts as a Preferred Site for Cleavage for Serine Proteases to Generate the Perfect C-lobe: Structure of the Pepsin Hydrolyzed Lactoferrin C-lobe at 2.28 angstrom Resolution. Protein J., 40, 2021
7KU1	Data clustering and dynamics of chymotrypsinogen cluster 139 (green) structure 分子名称: Chymotrypsinogen A, SULFATE ION 著者 Nguyen, T, Phan, K.L, Kreitler, D.F, Andrews, L.C, Gabelli, S.B, Kozakov, D, Jakoncic, J, Sweet, R.M, Soares, A.S, Bernstein, H.J. 登録日 2020-11-24 公開日 2021-03-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. Acta Crystallogr D Struct Biol, 78, 2022
1F9U	CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
5C00	MdbA protein, a thiol-disulfide oxidoreductase from Corynebacterium diphtheriae 分子名称: MdbA protein 著者 OSIPIUK, J, REARDON-ROBINSON, M.E, TON-THAT, H, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-06-11 公開日 2015-07-15 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 A thiol-disulfide oxidoreductase of the Gram-positive pathogen Corynebacterium diphtheriae is essential for viability, pilus assembly, toxin production and virulence. Mol.Microbiol., 98, 2015
4Y73	Crystal structure of IRAK4 kinase domain with inhibitor 分子名称: 5-{[(1R,2S)-2-aminocyclohexyl]amino}-N-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, Interleukin-1 receptor-associated kinase 4 著者 Lesburg, C.A. 登録日 2015-02-13 公開日 2015-05-20 最終更新日 2015-07-15 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4. Acs Med.Chem.Lett., 6, 2015
5JPL	LP2006, a handcuff-topology lasso peptide antibiotic 分子名称: Uncharacterized protein 著者 Tietz, J.I, Schwalen, C.J, Blair, P.M, Zakai, U.I, Mitchell, D.A. 登録日 2016-05-03 公開日 2017-03-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A new genome-mining tool redefines the lasso peptide biosynthetic landscape. Nat. Chem. Biol., 13, 2017
1F9T	CRYSTAL STRUCTURES OF KINESIN MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.-G, Park, H.-W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
7KGC	Crystal structure of a perchloric acid-soluble protein (PSP) from Trichomonas vaginalis at 1.95 A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Putative translation initiation inhibitor 著者 Diaz-Vilchis, A, Rudino-Pinera, E, Alvarez-Sanchez, M.E, Arreola, R. 登録日 2020-10-16 公開日 2021-10-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A Putative New Role of Tv-PSP1 Recognizes IRE and ERE Hairpin Structures from Trichomonas vaginalis. Pathogens, 12, 2023
5V18	Structure of PHD2 in complex with 1,2,4-Triazolo-[1,5-a]pyridine 分子名称: 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile, Egl nine homolog 1, FE (II) ION, ... 著者 Skene, R.J. 登録日 2017-03-01 公開日 2017-06-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction. J. Med. Chem., 60, 2017
1G90	NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers 分子名称: OUTER MEMBRANE PROTEIN A 著者 Arora, A, Abildgaard, F, Bushweller, J.H, Tamm, L.K. 登録日 2000-11-21 公開日 2001-04-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of outer membrane protein A transmembrane domain by NMR spectroscopy Nat.Struct.Biol., 8, 2001
6CP5	Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of oligomycin bound generated from focused refinement. 分子名称: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... 著者 Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. 登録日 2018-03-13 公開日 2018-04-11 最終更新日 2020-01-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
5TBO	Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM421 分子名称: 2-(1,1-difluoroethyl)-5-methyl-N-[6-(trifluoromethyl)pyridin-3-yl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... 著者 Deng, X, Phillips, M. 登録日 2016-09-12 公開日 2016-09-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria. ACS Infect Dis, 2, 2016
5CUO	Structure of Rhodopseudomonas palustris PduL - CoA bound form 分子名称: COENZYME A, Phosphate propanoyltransferase, ZINC ION 著者 Sutter, M, Erbilgin, O, Kerfeld, C.A. 登録日 2015-07-24 公開日 2016-03-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.544 Å) 主引用文献 The Structural Basis of Coenzyme A Recycling in a Bacterial Organelle. Plos Biol., 14, 2016
5UV5	Crystal Structure of a 2-Hydroxyisoquinoline-1,3-dione RNase H Active Site Inhibitor with Multiple Binding Modes to HIV Reverse Transcriptase 分子名称: 7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... 著者 Kirby, K.A, Sarafianos, S.G. 登録日 2017-02-19 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase. Antimicrob. Agents Chemother., 61, 2017

<55565758596061626364656667686970>