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1YUC
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Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to Phospholipid and a Fragment of Human SHP
分子名称: GLYCEROL, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor 0B2, ...
著者Ortlund, E.A, Yoonkwang, L, Solomon, I.H, Hager, J.M, Safi, R, Choi, Y, Guan, Z, Tripathy, A, Raetz, C.R.H, McDonnell, D.P, Moore, D.D, Redinbo, M.R.
登録日2005-02-13
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
Nat.Struct.Mol.Biol., 12, 2005
6TWL
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BU of 6twl by Molmil
Apo structure of the Ectoine utilization protein EutE (DoeB) from Ruegeria pomeroyi
分子名称: N-acetyl-L-2,4-diaminobutyric acid deacetylase
著者Mais, C.-N, Altegoer, F, Bange, G.
登録日2020-01-13
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex.
J.Biol.Chem., 295, 2020
4K95
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BU of 4k95 by Molmil
Crystal Structure of Parkin
分子名称: E3 ubiquitin-protein ligase parkin, ZINC ION
著者Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K.
登録日2013-04-19
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.499 Å)
主引用文献Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
3S3V
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BU of 3s3v by Molmil
human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim
分子名称: Dihydrofolate reductase, SULFATE ION, TRIMETHOPRIM
著者Cody, V, Pace, J, Piraino, J, Queener, S.F.
登録日2011-05-18
公開日2011-09-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase.
J.Struct.Biol., 176, 2011
4HH3
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BU of 4hh3 by Molmil
Structure of the AppA-PpsR2 core complex from Rb. sphaeroides
分子名称: AppA protein, Transcriptional regulator, PpsR
著者Winkler, A, Heintz, U, Lindner, R, Reinstein, J, Shoeman, R, Schlichting, I.
登録日2012-10-09
公開日2013-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A ternary AppA-PpsR-DNA complex mediates light regulation of photosynthesis-related gene expression.
Nat.Struct.Mol.Biol., 20, 2013
3DCT
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BU of 3dct by Molmil
FXR with SRC1 and GW4064
分子名称: 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid, Bile acid receptor, Nuclear receptor coactivator 1
著者Williams, S.P, Madauss, K.P.
登録日2008-06-04
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064.
Bioorg.Med.Chem.Lett., 18, 2008
3DCU
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BU of 3dcu by Molmil
FXR with SRC1 and GSK8062
分子名称: 6-(4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)naphthalene-1-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1
著者Williams, S.P, Madauss, K.P.
登録日2008-06-04
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064.
Bioorg.Med.Chem.Lett., 18, 2008
4MEA
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BU of 4mea by Molmil
Crystal structure of the Cif epoxide hydrolase from Acinetobacter nosocomialis
分子名称: Predicted protein
著者Bahl, C.D, Madden, D.R.
登録日2013-08-25
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Signature motifs identify an acinetobacter cif virulence factor with epoxide hydrolase activity.
J.Biol.Chem., 289, 2014
4MEB
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BU of 4meb by Molmil
Crystal structure of aCif-D158S
分子名称: GLYCEROL, PHOSPHATE ION, Predicted protein
著者Bridges, A.A, Bahl, C.D, Madden, D.R.
登録日2013-08-25
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Signature motifs identify an acinetobacter cif virulence factor with epoxide hydrolase activity.
J.Biol.Chem., 289, 2014
2BJ3
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BU of 2bj3 by Molmil
NIKR-apo
分子名称: CHLORIDE ION, MAGNESIUM ION, NICKEL RESPONSIVE REGULATOR
著者Tahirov, T.H.
登録日2005-01-28
公開日2005-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition
J.Mol.Biol., 348, 2005
6BW4
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BU of 6bw4 by Molmil
Crystal structure of RBBP4 in complex with PRDM16 N-terminal peptide
分子名称: Histone-binding protein RBBP4, PR domain zinc finger protein 16, UNKNOWN ATOM OR ION
著者Ivanochko, D, Halabelian, L, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2017-12-14
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
Nucleic Acids Res., 47, 2019
2CKL
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BU of 2ckl by Molmil
Ring1b-Bmi1 E3 catalytic domain structure
分子名称: IODIDE ION, POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ...
著者Buchwald, G, van der Stoop, P, Weichenrieder, O, Perrakis, A, van Lohuizen, M, Sixma, T.K.
登録日2006-04-20
公開日2006-05-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B.
Embo J., 25, 2006
3NAR
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BU of 3nar by Molmil
Crystal structure of ZHX1 HD4 (zinc-fingers and homeoboxes protein 1, homeodomain 4)
分子名称: SULFATE ION, Zinc fingers and homeoboxes protein 1
著者Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF)
登録日2010-06-02
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
2BJ7
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BU of 2bj7 by Molmil
NIKR IN CLOSED CONFORMATION AND NICKEL BOUND TO HIGH-AFFINITY SITES
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NICKEL (II) ION, ...
著者Tahirov, T.H.
登録日2005-01-31
公開日2005-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition
J.Mol.Biol., 348, 2005
2BJ1
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BU of 2bj1 by Molmil
NIKR IN OPEN CONFORMATION AND NICKEL BOUND TO HIGH-AFFINITY SITES
分子名称: CHLORIDE ION, NICKEL (II) ION, NICKEL RESPONSIVE REGULATOR
著者Tahirov, T.H.
登録日2005-01-27
公開日2005-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition
J.Mol.Biol., 348, 2005
2CAJ
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BU of 2caj by Molmil
NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 4 intermediary sites
分子名称: CHLORIDE ION, GLYCEROL, NICKEL (II) ION, ...
著者Dian, C, Schauer, K, Kapp, U, McSweeney, S.M, Labigne, A, Terradot, L.
登録日2005-12-21
公開日2006-07-17
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis of the Nickel Response in Helicobacter Pylori: Crystal Structures of Hpnikr in Apo and Nickel-Bound States.
J.Mol.Biol., 361, 2006
2B1D
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BU of 2b1d by Molmil
5'-D(*GP*CP*AP*GP*AP*CP*GP*TP*CP*TP*GP*C)-3' Methionine Repressor binding site
分子名称: 5'-D(*GP*CP*AP*GP*AP*CP*GP*TP*CP*TP*GP*C)-3', COBALT HEXAMMINE(III), MAGNESIUM ION
著者Berman, H.M, Locasale, J.W, Napoli, A.A.
登録日2005-09-15
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Signatures of protein-DNA recognition in free DNA binding sites.
J.Mol.Biol., 386, 2009
3EZT
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BU of 3ezt by Molmil
Crystal Structure Analysis of Human HDAC8 D101E Variant
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ...
著者Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W.
登録日2008-10-23
公開日2008-12-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry, 47, 2008
6Y17
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BU of 6y17 by Molmil
Crystal structure of an NCoR1BBD2-BCL6BTB chimera in complex with nebulinSH3-NCoR1BBD1
分子名称: Nebulin,Nuclear receptor corepressor 1, Nuclear receptor corepressor 1,B-cell lymphoma 6 protein, SODIUM ION
著者Zacharchenko, T, Wright, S.C.
登録日2020-02-11
公開日2020-12-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Functionalization of the BCL6 BTB domain into a noncovalent crystallization chaperone.
Iucrj, 8, 2021
1RV4
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BU of 1rv4 by Molmil
E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE
分子名称: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ...
著者Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V.
登録日2003-12-12
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
1RVY
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BU of 1rvy by Molmil
E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE, COMPLEX WITH GLYCINE
分子名称: N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
著者Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V.
登録日2003-12-15
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
7BCB
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BU of 7bcb by Molmil
Crystal structure of the HTH DNA binding protein ArdK from R388 plasmid bound to IR3 DNA
分子名称: DNA (5'-D(*TP*AP*AP*TP*GP*TP*CP*AP*AP*AP*TP*AP*TP*TP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*AP*TP*AP*TP*TP*TP*GP*AP*CP*AP*TP*TP*A)-3'), KORA domain-containing protein
著者Fernandez-Lopez, R, Boer, D.R, Moncalian, G.
登録日2020-12-19
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of direct and inverted DNA sequence repeat recognition by helix-turn-helix transcription factors.
Nucleic Acids Res., 50, 2022
3EZP
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BU of 3ezp by Molmil
Crystal Structure Analysis of human HDAC8 D101N variant
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ...
著者Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W.
登録日2008-10-23
公開日2008-12-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry, 47, 2008
3F0R
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BU of 3f0r by Molmil
Crystal Structure Analysis of Human HDAC8 complexed with trichostatin A in a new monoclinic crystal form
分子名称: Histone deacetylase 8, POTASSIUM ION, TRICHOSTATIN A, ...
著者Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W.
登録日2008-10-25
公開日2008-12-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry, 47, 2008
3EW8
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BU of 3ew8 by Molmil
Crystal Structure Analysis of human HDAC8 D101L variant
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, GLYCEROL, ...
著者Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W.
登録日2008-10-14
公開日2008-12-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry, 47, 2008

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