PDB: 13413 件ウェブページステータス検索Chemie searchBIRD

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7DI0	Crystal structure of the rationally designed apDPBB_sym_79 protein 分子名称: SULFATE ION, apDPBB_sym_79 protein 著者 Yagi, S, Tagami, S. 登録日 2020-11-18 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase. J.Am.Chem.Soc., 143, 2021
8Q63	Cryo-EM structure of IC8', a second state of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG 分子名称: DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Goovaerts, Q, Shen, J, Patel, S.S, Das, K. 登録日 2023-08-10 公開日 2023-08-30 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
8PDY	E. coli RNA polymerase paused at ops site 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. 登録日 2023-06-13 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
8PH9	E. coli RNA polymerase paused at ops site (non-complementary scaffold) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. 登録日 2023-06-19 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
8C4V	Hantaan virus polymerase in replication elongation state 分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*CP*UP*AP*CP*UP*A)-3'), RNA (5'-R(P*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), ... 著者 Durieux trouilleton, Q, Arragain, B, Malet, H. 登録日 2023-01-04 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication. Nat Commun, 14, 2023
8C4U	Hantaan virus polymerase in replication pre-initiation state 分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*GP*CP*GP*GP*AP*GP*UP*AP*CP*UP*AP*CP*UP*A)-3'), ... 著者 Durieux trouilleton, Q, Arragain, B, Malet, H. 登録日 2023-01-04 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication. Nat Commun, 14, 2023
8C4T	Hantaan virus polymerase bound to its 5' viral RNA 分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L 著者 Durieux trouilleton, Q, Arragain, B, Malet, H. 登録日 2023-01-04 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication. Nat Commun, 14, 2023
4WSB	Bat Influenza A polymerase with bound vRNA promoter 分子名称: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ... 著者 Cusack, S, Pflug, A, Guilligay, D, Reich, S. 登録日 2014-10-26 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
7ZSB	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2022-05-06 公開日 2022-11-16 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7ZSA	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2022-05-06 公開日 2022-11-16 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7ZS9	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2022-05-06 公開日 2022-11-16 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
4WRT	Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) 分子名称: Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ... 著者 Reich, S, Guilligay, D, Pflug, A, Cusack, S. 登録日 2014-10-25 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
4WSA	Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) 分子名称: Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ... 著者 Reich, S, Guilligay, D, Pflug, A, Cusack, S. 登録日 2014-10-26 公開日 2014-11-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
8JCH	Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol II Rat1-PTTC1) 分子名称: 5'-3' exoribonuclease 2, DNA (38-MER), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Zeng, Y, Zhang, Y. 登録日 2023-05-11 公開日 2024-01-31 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis of exoribonuclease-mediated mRNA transcription termination. Nature, 628, 2024
8K5P	Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 2 (Pol II Rat1-PTTC2) 分子名称: 5'-3' exoribonuclease 2, DNA (38-MER), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Zeng, Y, Zhang, Y. 登録日 2023-07-23 公開日 2024-01-31 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of exoribonuclease-mediated mRNA transcription termination. Nature, 628, 2024
8C5U	Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG (IC8) 分子名称: DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Goovaerts, Q, Shen, J, Patel, S.S, Das, K. 登録日 2023-01-10 公開日 2023-08-30 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
8C5S	Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer RNA, pppGpGpUpApApApU (IC7) 分子名称: DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Goovaerts, Q, Shen, J, Patel, S.S, Das, K. 登録日 2023-01-10 公開日 2023-08-30 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
8TVY	Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) 分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Sarsam, R.D, Lahiri, I, Leschziner, A.E. 登録日 2023-08-18 公開日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
4WTD	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH ADP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AUAAAUUU 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Edwards, T.E, Fox III, D, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTF	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GS-639475, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU 分子名称: 2'-C-methyluridine 5'-(trihydrogen diphosphate), CHLORIDE ION, MANGANESE (II) ION, ... 著者 Edwards, T.E, Appleby, T.C, Mcgrath, M.E. 登録日 2014-10-30 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTA	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH UDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU 分子名称: CHLORIDE ION, MANGANESE (II) ION, RNA PRIMER TEMPLATE CAAAAUUU, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTC	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH CDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AGAAAUUU 分子名称: CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTE	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-ACAAAUUU 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTG	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH SOFOSBUVIR DIPHOSPHATE GS-607596, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU 分子名称: 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), CHLORIDE ION, MANGANESE (II) ION, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-30 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WT9	APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH E86Q E87Q S15G C223H V321I AND DELTA8 MUTATIONS 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015

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