9FE8
| Crystal Structure of reduced NuoEF variant P228R(NuoF) from Aquifex aeolicus | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | 登録日 | 2024-05-17 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I). Biochim Biophys Acta Bioenerg, 1865, 2024
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4K1V
| Crystal structure of delta5-3-ketosteroid isomerase containing Y16F and Y57F mutations | 分子名称: | Steroid Delta-isomerase | 著者 | Cha, H.J, Jang, D.S, Kim, Y.G, Hong, B.H, Woo, J.S, Choi, K.Y. | 登録日 | 2013-04-05 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rescue of deleterious mutations by the compensatory Y30F mutation in ketosteroid isomerase Mol.Cells, 36, 2013
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9IIW
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9BIY
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9BNQ
| N-(4-(isothiocyanatomethyl)phenyl)methanesulfonamide complexed with Macrophage Migration Inhibitory Factor | 分子名称: | ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, N-{[4-(methanesulfonamido)phenyl]methyl}methanethioamide, ... | 著者 | Fellner, M, Rutledge, M.T, Putha, L, Kok, L.K, Gamble, A.B, Wilbanks, S.M, Vernall, A.J, Tyndall, J.D.A. | 登録日 | 2024-05-02 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments. Chemmedchem, 2024
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4JYG
| Crystal structure of RARbeta LBD in complex with agonist BMS411 [4-{[(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)carbonyl]amino}benzoic acid] | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-{[(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)carbonyl]amino}benzoic acid, CITRATE ANION, ... | 著者 | Nadendla, E.K, Teyssier, C, Germain, P, Delfosse, V, Bourguet, W. | 登録日 | 2013-03-29 | 公開日 | 2014-03-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor beta (RAR beta , NR1B2) Selective Agonist. Plos One, 10, 2015
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9BJ0
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9FST
| Yeast 20S proteasome with human beta1i (1-51) in complex with epoxyketone inhibitor LU-001i | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | 登録日 | 2024-06-21 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites To Be Published
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4JZG
| Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile | 分子名称: | MANGANESE (II) ION, Superoxide dismutase | 著者 | Li, W, Wang, C.L, Zhao, Y, Wang, H.F, Tan, S.X. | 登録日 | 2013-04-02 | 公開日 | 2014-04-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.321 Å) | 主引用文献 | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile To be Published
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9FE0
| Crystal Structure of reduced NuoEF variant R66G(NuoF) from Aquifex aeolicus bound to NAD+ | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | 登録日 | 2024-05-17 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I). Biochim Biophys Acta Bioenerg, 1865, 2024
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4JYT
| Crystal Structure of Matriptase in complex with Inhibitor | 分子名称: | 4,4'-[{3-[(naphthalen-2-ylsulfonyl)amino]pyridine-2,6-diyl}bis(oxy)]dibenzenecarboximidamide, Suppressor of tumorigenicity 14 protein | 著者 | Subramanya, H.S, Ravi, B.C, Ashok, K.N, Chakshusmathi, G, Ramesh, K.S. | 登録日 | 2013-04-01 | 公開日 | 2014-03-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors ACS MED.CHEM.LETT., 4, 2013
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9FIF
| Crystal Structure of NuoEF variant P228R(NuoF) from Aquifex aeolicus bound to NADH under anoxic conditions | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | 登録日 | 2024-05-29 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I). Biochim Biophys Acta Bioenerg, 1865, 2024
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4K1S
| Gly-Ser-SplB protease from Staphylococcus aureus at 1.96 A resolution | 分子名称: | Serine protease SplB | 著者 | Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G. | 登録日 | 2013-04-05 | 公開日 | 2014-04-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation. J.Biol.Chem., 289, 2014
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4JZI
| Crystal Structure of Matriptase in complex with Inhibitor". | 分子名称: | N-(trans-4-aminocyclohexyl)-2,6-bis(4-carbamimidoylphenoxy)pyridine-4-carboxamide, Suppressor of tumorigenicity 14 protein | 著者 | Subramanya, H.S, Chandra, R.B, Ashok, K.N, Chakshusmathi, G, Ramesh, K.S. | 登録日 | 2013-04-03 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors ACS MED.CHEM.LETT., 4, 2013
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9EQF
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4JZL
| Crystal structure of BAP31 vDED at alkaline pH | 分子名称: | B-cell receptor-associated protein 31, GLYCEROL | 著者 | Quistgaard, E.M, Low, C, Moberg, P, Guettou, F, Maddi, K, Nordlund, P. | 登録日 | 2013-04-03 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and Biophysical Characterization of the Cytoplasmic Domains of Human BAP29 and BAP31. Plos One, 8, 2013
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6D7C
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9BRV
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9FJC
| Compact CVB1-VLP (Tween80) | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Plavec, Z, Butcher, S.J. | 登録日 | 2024-05-30 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Comparison of structure and immunogenicity of CVB1-VLP and inactivated CVB1 vaccine candidates. Res Sq, 2024
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9FX7
| Crystal structure of Cryo2RT SARS-CoV-2 main protease at 294K | 分子名称: | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Huang, C.Y, Aumonier, S, Mac Sweeney, A, Olieric, V, Wang, M. | 登録日 | 2024-07-01 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.282 Å) | 主引用文献 | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
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9FQI
| E3 ligase Cbl-b in complex with a lactam scaffold inhibitor (compound 7) | 分子名称: | 8-[3-[(4~{R})-4-methyl-2-oxidanylidene-piperidin-4-yl]phenyl]-3-[[(3~{S})-3-methylpiperidin-1-yl]methyl]-5-(trifluoromethyl)-1$l^{4},7,8-triazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... | 著者 | Schimpl, M. | 登録日 | 2024-06-17 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Accelerated Discovery of a Carbamate Scaffold Cbl-b Inhibitor using Generative Models and Structure-Based Drug Design To be published
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6DFX
| human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Y, Dai, S. | 登録日 | 2018-05-15 | 公開日 | 2019-04-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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9ILD
| Complex structure of Cap3 and CD-NTase | 分子名称: | Cyclic GMP-AMP synthase, Peptidase, ZINC ION | 著者 | Li, F.Q, Ma, W.F. | 登録日 | 2024-06-29 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (2.179 Å) | 主引用文献 | Structural and functional characterization of the bacterial Cap3 enzyme in deconjugation and regulation of the cyclic dinucleotide transferase CD-NTase To Be Published
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9C1Q
| Crystal structure of the WDR domain of human DCAF1 in complex with OICR-39512 compound | 分子名称: | (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-(3-methoxyprop-1-yn-1-yl)-1H-pyrrole-3-carboxamide, CHLORIDE ION, DDB1- and CUL4-associated factor 1, ... | 著者 | kimani, S, Dong, A, Li, Y, Seitova, A, Al-awar, R, Wilson, B, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L. | 登録日 | 2024-05-29 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-39512 compound To be published
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4JZ1
| Crystal Structure of Matriptase in complex with Inhibitor | 分子名称: | 4,4'-[(3-{[(4-fluorophenyl)sulfonyl]amino}pyridine-2,6-diyl)bis(oxy)]dibenzenecarboximidamide, Suppressor of tumorigenicity 14 protein | 著者 | Subramanya, H.S, Ravi, B.C, Ashok, K.N, Chakshusmathi, G, Ramesh, K.S. | 登録日 | 2013-04-02 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors ACS MED.CHEM.LETT., 4, 2013
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