PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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6MU5	Bst DNA polymerase I TNA/DNA binary complex 分子名称: DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, SULFATE ION, ... 著者 Jackson, L.N, Chim, N, Chaput, J.C. 登録日 2018-10-22 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.912 Å) 主引用文献 Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase. Nucleic Acids Res., 47, 2019
8PRT	The structure of nvBagel8 in the presence of Co(II) 分子名称: COBALT (II) ION, Cell surface protein 著者 Vandebroek, L, Voet, A.R.D, Lee, X.Y. 登録日 2023-07-12 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The structure of nvBagel8 in the presence of Co(II) To Be Published
8PRG	The structure of nvBagel6 分子名称: Cell surface protein 著者 Vandebroek, L, Voet, A.R.D, Lee, X.Y. 登録日 2023-07-12 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The structure of v13Bagel2 To Be Published
8DRV	Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp8-nsp9 (C8) cut site sequence 分子名称: Fusion protein of 3C-like proteinase nsp5 and nsp8-nsp9 (C8) cut site, PENTAETHYLENE GLYCOL 著者 Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. 登録日 2022-07-21 公開日 2022-09-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
8E54	MicroED structure of triclinic lysozyme recorded on K3 分子名称: Lysozyme C, NITRATE ION 著者 Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. 登録日 2022-08-19 公開日 2022-09-21 最終更新日 2022-10-19 実験手法 ELECTRON CRYSTALLOGRAPHY (1.2 Å) 主引用文献 Electron-counting MicroED data with the K2 and K3 direct electron detectors. J.Struct.Biol., 214, 2022
8PT5	ERK2 covelently bound to RU187 cyclohexenone based inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Sok, P, Poti, A, Remenyi, A. 登録日 2023-07-13 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a Michael acceptor-based cyclic warhead scaffold To Be Published
6N4G	Crystal structure of a tetrameric DNA fold-back quadruplex 分子名称: BARIUM ION, DNA (5'-D(*CP*GP*TP*TP*AP*GP*GP*CP*G)-3') 著者 Chu, B, Paukstelis, P.J. 登録日 2018-11-19 公開日 2018-12-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of a Tetrameric DNA Fold-Back Quadruplex. J. Am. Chem. Soc., 140, 2018
5AF1	Crystal structure of Candida albicans Mep2 分子名称: MEP2 著者 Rutherford, J.C, Chembath, A, van den Berg, B. 登録日 2015-01-14 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.639 Å) 主引用文献 Structural Basis for Mep2 Ammonium Transceptor Activation by Phosphorylation. Nat.Commun., 7, 2016
8PG4	Crystal structure of the metallo-beta-lactamase VIM1 with 2730 分子名称: 3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-7-[(1~{R})-1-(1~{H}-1,2,3-triazol-5-ylmethoxy)ethyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION 著者 Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. 登録日 2023-06-18 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal structure of the metallo-beta-lactamase VIM1 with 2730 To Be Published
7PBB	Crystal structure of CD73 in complex with caffeine in the open form 分子名称: 5'-nucleotidase, CAFFEINE, CALCIUM ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-08-01 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
6BFN	Crystal structure of human IRAK1 分子名称: Interleukin-1 receptor-associated kinase 1, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide 著者 Wang, L, Qiao, Q, Wu, H. 登録日 2017-10-26 公開日 2017-12-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Crystal structure of human IRAK1. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8PGV	Crystal structure of the metallo-beta-lactamase VIM1 with 3396 分子名称: 7-[(1~{S})-1-[2-(aminomethyl)-6-oxidanylidene-5-oxa-7-azaspiro[3.4]octan-7-yl]ethyl]-3-[3-fluoranyl-4-(oxetan-3-ylsulfonylamino)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION 著者 Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. 登録日 2023-06-18 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Crystal structure of the metallo-beta-lactamase VIM1 with 3396 To Be Published
8DRU	Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence 分子名称: DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp7-nsp8 (C7) cut site, PENTAETHYLENE GLYCOL, ... 著者 Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. 登録日 2022-07-21 公開日 2022-09-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
8DPJ	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023030 分子名称: (2P)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-2-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-07-15 公開日 2022-09-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
8PJU	Crystal structure of the computationally designed SAKe6DEtal protein 分子名称: SAKe6DEtal 著者 Wouters, S.M.L. 登録日 2023-06-23 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Computational design of the SAKe scaffold proteins To Be Published
6PAK	Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Subtilisin E 著者 Tang, H, Shi, K, Aihara, H. 登録日 2019-06-11 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Enhancing subtilisin thermostability through a modified normalized B-factor analysis and loop-grafting strategy. J.Biol.Chem., 294, 2019
6N50	Metabotropic Glutamate Receptor 5 Extracellular Domain in Complex with Nb43 and L-quisqualic acid 分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... 著者 Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Skiniotis, G, Mathiesen, J.M, Kobilka, B.K. 登録日 2018-11-20 公開日 2019-01-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.751 Å) 主引用文献 Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
6PD8	Crystal structure of MYST acetyltransferase domain in complex with inhibitor 39 分子名称: 5-ethoxy-2-fluoro-3-methyl-N'-(phenylsulfonyl)benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ... 著者 Hermans, S.J, Parker, M.W, Thomas, T, Baell, J.B. 登録日 2019-06-18 公開日 2020-04-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.738 Å) 主引用文献 Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents. J.Med.Chem., 63, 2020
8PMF	transcription factor BARHL2 bound to DNA sequences 分子名称: BarH-like 2 homeobox protein, DNA 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2023-06-28 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 transcription factor BARHL2 bound to DNA sequences To Be Published
8E53	MicroED structure of proteinase K recorded on K3 分子名称: CALCIUM ION, Proteinase K 著者 Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. 登録日 2022-08-19 公開日 2022-09-21 最終更新日 2022-10-19 実験手法 ELECTRON CRYSTALLOGRAPHY (1.7 Å) 主引用文献 Electron-counting MicroED data with the K2 and K3 direct electron detectors. J.Struct.Biol., 214, 2022
6B2G	P38A mutant of HIV-1 capsid protein 分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION 著者 Gres, A.T, Kirby, K.A, Sarafianos, S.G. 登録日 2017-09-20 公開日 2018-09-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
7P9N	Crystal structure of CD73 in complex with AMP in the open form 分子名称: 5'-nucleotidase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-07-27 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
8EBF	C-terminal (TPR) domain of LIC11990 from Leptospira interrogans 分子名称: ACETATE ION, Cytoplasmic membrane protein, GLYCEROL 著者 Larrieux, N, Buschiazzo, A. 登録日 2022-08-31 公開日 2022-09-21 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and function of a novel membrane-associated protein from Leptospira interrogans (gene LIC11990) To Be Published
6B1W	Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by co-crystallization 分子名称: (2S,5R)-1-formyl-N'-[(3R)-piperidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide, CHLORIDE ION, Carbapenem-hydrolyzing beta-lactamase KPC, ... 著者 van den Akker, F, Nguyen, N.Q. 登録日 2017-09-19 公開日 2018-08-01 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using beta-Lactamase Inhibitors and beta-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234. J. Med. Chem., 61, 2018
8E21	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023034 分子名称: 5-hydroxy-6-oxo-N-[2-(pyridin-4-yl)ethyl]-2-{[2-(trifluoromethyl)phenyl]methyl}-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-08-12 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023034 To Be Published

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