PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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4C1P	Geobacillus thermoglucosidasius GH family 52 xylosidase 分子名称: BETA-XYLOSIDASE, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... 著者 Espina, G, Eley, K, Schneider, T.R, Crennell, S.J, Danson, M.J. 登録日 2013-08-13 公開日 2014-05-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.634 Å) 主引用文献 A Novel Beta-Xylosidase Structure from Geobacillus Thermoglucosidasius: The First Crystal Structure of a Glycoside Hydrolase Family Gh52 Enzyme Reveals Unpredicted Similarity to Other Glycoside Hydrolase Folds Acta Crystallogr.,Sect.D, 70, 2014
4CCX	ALTERING SUBSTRATE SPECIFICITY AT THE HEME EDGE OF CYTOCHROME C PEROXIDASE 分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE 著者 Wilcox, S.K, Jensen, G.M, Fitzgerald, M.M, Mcree, D.E, Goodin, D.B. 登録日 1995-03-17 公開日 1995-07-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Altering substrate specificity at the heme edge of cytochrome c peroxidase. Biochemistry, 35, 1996
7K2V	PIKfyve/Fig4/Vac14 complex centered on PIKfyve - map2 分子名称: 1-phosphatidylinositol 3-phosphate 5-kinase 著者 Lees, J.A, Reinisch, K.M, Li, P. 登録日 2020-09-09 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex. Mol.Cell, 80, 2020
7K1W	PIKfyve/Fig4/Vac14 complex centered on Fig4 - map3 分子名称: Fig4 Sac homology model 著者 Lees, J.A, Reinisch, K.M, Li, P. 登録日 2020-09-08 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex. Mol.Cell, 80, 2020
6EYU	Crystal structure of the inward H(+) pump xenorhodopsin 分子名称: Bacteriorhodopsin, EICOSANE, RETINAL, ... 著者 Kovalev, K, Shevchenko, V, Polovinkin, V, Mager, T, Gushchin, I, Melnikov, I, Borshchevskiy, V, Popov, A, Alekseev, A, Gordeliy, V. 登録日 2017-11-13 公開日 2017-12-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Inward H(+) pump xenorhodopsin: Mechanism and alternative optogenetic approach. Sci Adv, 3, 2017
5IHL	STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE CD40 IN COMPLEX WITH 3H56-5 DAB 分子名称: 3H56-5 domain antibody (dAb), SULFATE ION, Tumor necrosis factor receptor superfamily member 5 著者 Sheriff, S. 登録日 2016-02-29 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. J.Mol.Biol., 428, 2016
2MW1	NMR structure of the protein NP_809137.1 from Bacteroides thetaiotaomicron 分子名称: Lipocalin-like protein 著者 Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG) 登録日 2014-10-27 公開日 2014-11-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of the protein NP_809137.1 from Bacteroides thetaiotaomicron To be Published
4E7D	E. cloacae MurA in complex with UDP 分子名称: 1,2-ETHANEDIOL, ACETATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2012-03-16 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Open-close transition of MurA To be Published
2MQF	NMR structure of spider toxin-TRTX-Hhn2b 分子名称: Mu-theraphotoxin-Hhn2b 著者 Klint, J.K, Chin, Y.K.Y, Mobli, M. 登録日 2014-06-19 公開日 2015-07-15 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88, 2015
4EBK	Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound 分子名称: 1,2-ETHANEDIOL, Aminoglycoside nucleotidyltransferase, CHLORIDE ION, ... 著者 Stogios, P.J, Dong, A, Minasov, G, Evdokimova, E, Egorova, O, Yim, V, Kudritska, M, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-03-23 公開日 2012-04-04 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound To be Published
4EC0	Crystal structure of hH-PGDS with water displacing inhibitor 分子名称: 4-[2-(aminomethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide, GLUTATHIONE, Hematopoietic prostaglandin D synthase, ... 著者 Day, J.E, Thorarensen, A, Trujillo, J.I. 登録日 2012-03-26 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters. Bioorg.Med.Chem.Lett., 22, 2012
4E7G	E. cloacae C115D/R120A MurA in the unliganded state 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2012-03-16 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Open-close transition of MurA To be Published
5IV0	Crystal structure of Eis from Mycobacterium tuberculosis in complex with sulfonamide inhibitor 39 and coenzyme A 分子名称: CHLORIDE ION, COENZYME A, Enhanced intracellular survival protein, ... 著者 Gajadeera, C.S, Hou, C, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2016-03-18 公開日 2017-01-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis. J. Med. Chem., 59, 2016
7K1Y	PIKfyve/Fig4/Vac14 complex centered on Vac14 - map1 分子名称: Vac14 著者 Lees, J.A, Reinisch, K.M, Li, P. 登録日 2020-09-08 公開日 2020-10-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (5.25 Å) 主引用文献 Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex. Mol.Cell, 80, 2020
4ERL	Crystal structure of the lysine riboswitch bound to a lysine-glycine dipeptide 分子名称: GLYCINE, LYSINE, Lysine riboswitch RNA 著者 Garst, A.D, Porter, E, Batey, R.T. 登録日 2012-04-20 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Insights into the regulatory landscape of the lysine riboswitch. J.Mol.Biol., 423, 2012
1ZJ4	Crystal Structure Analysis of the dienelactone hydrolase mutant (E36D, C123S) bound with the PMS moiety of the protease inhibitor, Phenylmethylsulfonyl fluoride (PMSF)- 1.7 A 分子名称: Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION 著者 Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. 登録日 2005-04-28 公開日 2005-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase. Acta Crystallogr.,Sect.D, 61, 2005
5J58	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1856) 分子名称: (3S)-1-(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-N-[(3,5-dichlorophenyl)methyl]piperidin-3-amine, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Barros-Alvarez, X, Hol, W.G.J. 登録日 2016-04-01 公開日 2017-01-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. Eur J Med Chem, 124, 2016
4ED6	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 6.7 for 15 hr, Sideway translocation 分子名称: DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... 著者 Nakamura, T, Zhao, Y, Yang, W. 登録日 2012-03-27 公開日 2012-07-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.211 Å) 主引用文献 Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
6FIY	Crystal structure of a dye-decolorizing peroxidase D143AR232A variant from Klebsiella pneumoniae (KpDyP) 分子名称: GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... 著者 Pfanzagl, V, Hofbauer, S, Mlynek, G. 登録日 2018-01-19 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.09000432 Å) 主引用文献 Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage. J. Biol. Chem., 293, 2018
6EST	INTERACTION OF THE PEPTIDE CF3-LEU-ALA-NH-C6H4-CF3(TFLA) WITH PORCINE PANCREATIC ELASTASE. X-RAY STUDIES AT 1.8 ANGSTROMS 分子名称: CALCIUM ION, DIMETHYLFORMAMIDE, PORCINE PANCREATIC ELASTASE, ... 著者 Prange, T, Li De Lasierra, I. 登録日 1990-06-15 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Interaction of the peptide CF3-Leu-Ala-NH-C6H4-CF3 (TFLA) with porcine pancreatic elastase. X-ray studies at 1.8 A. J.Mol.Recog., 3, 1990
2NAO	Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibril 分子名称: Beta-amyloid protein 42 著者 Waelti, M.A, Ravotti, F, Arai, H, Glabe, C, Wall, J, Bockmann, A, Guntert, P, Meier, B.H, Riek, R. 登録日 2016-01-07 公開日 2016-07-27 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Atomic-resolution structure of a disease-relevant A beta (1-42) amyloid fibril. Proc.Natl.Acad.Sci.USA, 113, 2016
1W7B	Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein. 分子名称: ANNEXIN A2 著者 Rosengarth, A, Luecke, H. 登録日 2004-09-01 公開日 2004-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Annexin A2: Does It Induce Membrane Aggregation by a New Multimeric State of the Protein Annexins, 1, 2004
5JFC	NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) from Pyrococcus furiosus 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... 著者 Zadvornyy, O.A, Schut, G.J, Nguyen, D.M, Artz, J.H, Tokmina-Lukaszewska, M, Lipscomb, G, King, P.W, Adams, M.W, Peters, J.W. 登録日 2016-04-19 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.598 Å) 主引用文献 Mechanistic insights into energy conservation by flavin-based electron bifurcation. Nat. Chem. Biol., 13, 2017
7THF	Structure of Cyclophilin D Peptidyl-Prolyl Isomerase Domain bound to Macrocyclic Inhibitor B53 分子名称: 3-(4'-{[(4S,7S,11R,13E,19S)-19-{[2-(2-aminoethoxy)ethyl]carbamoyl}-7-benzyl-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosin-4-yl]methyl}[1,1'-biphenyl]-4-yl)pentanedioic acid, Peptidyl-prolyl cis-trans isomerase F, mitochondrial 著者 Rangwala, A.M, Thakur, M.K, Seeliger, M.A, Peterson, A.A, Liu, D.R. 登録日 2022-01-10 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nat.Chem.Biol., 18, 2022
7TGV	Structure of Cyclophilin D Peptidyl-Prolyl Isomerase Domain bound to Macrocyclic Inhibitor B2 分子名称: (4S,7S,11R,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-7-benzyl-4-[([1,1'-biphenyl]-4-yl)methyl]-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial 著者 Rangwala, A.M, Thakur, M.K, Seeliger, M.A, Peterson, A.A, Liu, D.R. 登録日 2022-01-09 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nat.Chem.Biol., 18, 2022

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