7TOR
| Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20 | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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3CCQ
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5T2A
| CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution | 分子名称: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Zhang, X, Lai, M, Zhou, Z.H. | 登録日 | 2016-08-23 | 公開日 | 2017-01-25 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
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7UG6
| Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W. | 登録日 | 2022-03-24 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Nat.Struct.Mol.Biol., 30, 2023
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7LL9
| D-Protein RFX-V2 Bound to the VEGFR1 Domain 3 Site on VEGF-A | 分子名称: | Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V2 | 著者 | Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S. | 登録日 | 2021-02-03 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth. Acs Chem.Biol., 16, 2021
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6WOO
| CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal rRNA, ... | 著者 | Wang, J, Wang, J, Puglisi, J, Fernandez, I.S. | 登録日 | 2020-04-25 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity. To Be Published
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8OJ5
| 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Penchev, I, DaRosa, P.A, Peter, J.J, Kulathu, Y, Becker, T, Beckmann, R, Kopito, R. | 登録日 | 2023-03-23 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
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2OS7
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1GPA
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41BI
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1QVG
| Structure of CCA oligonucleotide bound to the tRNA binding sites of the large ribosomal subunit of Haloarcula marismortui | 分子名称: | 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ... | 著者 | Schmeing, T.M, Moore, P.B, Steitz, T.A. | 登録日 | 2003-08-27 | 公開日 | 2003-11-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit RNA, 9, 2003
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3CCL
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3CCV
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2XV7
| Crystal structure of vascular endothelial growth factor D | 分子名称: | VASCULAR ENDOTHELIAL GROWTH FACTOR D, alpha-D-mannopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Leppanen, V.-M, Jeltsch, M, Anisimov, A, Tvorogov, D, Aho, K, Kalkkinen, N, Toivanen, P, Yla-Herttuala, S, Ballmer-Hofer, K, Alitalo, K. | 登録日 | 2010-10-23 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Determinants of Vascular Endothelial Growth Factor-D - Receptor Binding and Specificity. Blood, 117, 2011
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2QEX
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8RJC
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6T9D
| Crystal structure of a bispecific DutaFab in complex with human VEGF121 | 分子名称: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | 著者 | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | 登録日 | 2019-10-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.905 Å) | 主引用文献 | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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8FL0
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7AQR
| Cryo-EM structure of Arabidopsis thaliana Complex-I (peripheral arm) | 分子名称: | Acyl carrier protein 2, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Klusch, N, Kuehlbrandt, W, Yildiz, O. | 登録日 | 2020-10-22 | 公開日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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2ZJR
| Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | 登録日 | 2008-03-08 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol.Cell, 30, 2008
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6V3B
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7M4Z
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3W0L
| The crystal structure of Xenopus Glucokinase and Glucokinase Regulatory Protein complex | 分子名称: | FRUCTOSE -6-PHOSPHATE, Glucokinase, Glucokinase regulatory protein, ... | 著者 | Choi, J.M, Seo, M.H, Kyeong, H.H, Kim, E, Kim, H.S. | 登録日 | 2012-10-31 | 公開日 | 2013-07-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase Proc.Natl.Acad.Sci.USA, 110, 2013
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5HFU
| Crystal Structure of Human Hexokinase 2 with cmpd 27, a 2-amido-6-benzenesulfonamide glucosamine | 分子名称: | Hexokinase-2, ~{N}-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-[[(4-cyanophenyl)sulfonylamino]methyl]-2,4,5-tris(oxidanyl)oxan-3-yl]-3-phenyl-benzamide | 著者 | Campobasso, N, Zhao, B, Smallwood, A. | 登録日 | 2016-01-07 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.923 Å) | 主引用文献 | Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors. Acs Med.Chem.Lett., 7, 2016
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8RXH
| CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN | 分子名称: | (2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid, 40S ribosomal protein S12, 40S ribosomal protein S14, ... | 著者 | Rajan, K.S, Yonath, A. | 登録日 | 2024-02-07 | 公開日 | 2024-05-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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