PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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6KZS	Crystal structure of cytochrome P450mel 107F1 in complex with heme and imidazole 分子名称: Cytochrome P-450, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE 著者 Hou, X.D, Rao, Y.J, Icyishaka, P, Li, C.X, Lou, J.L. 登録日 2019-09-25 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Crystallization and X-ray analysis of cytochrome P450mel 107F1 with biaryl coupling reactivity To Be Published
4UYM	Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole 分子名称: 14-ALPHA STEROL DEMETHYLASE, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2014-09-02 公開日 2015-08-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure-Functional Characterization of Cytochrome P450 Sterol Alpha-Demethylase (Cyp51B) from Aspergillus Fumigatus and Molecular Basis for the Development of Antifungal Drugs J.Biol.Chem., 290, 2015
6KZT	Crystal structure of cytochrome P450mel 107F1 with biaryl coupling reactivity 分子名称: Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE 著者 Hou, X.D, Rao, Y.J, Icyishaka, P, Li, C.X, Lou, J.L. 登録日 2019-09-25 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystallization and X-ray analysis of cytochrome P450mel 107F1 with biaryl coupling reactivity To Be Published
6L3A	Cytochrome P450 107G1 (RapN) with everolimus 分子名称: Cytochrome P450, Everolimus, PROTOPORPHYRIN IX CONTAINING FE 著者 Km, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. 登録日 2019-10-10 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
6L8I	Crystal structure of CYP97A3 mutant S290D/W300L/S304V 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Protein LUTEIN DEFICIENT 5, chloroplastic 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
6L39	Cytochrome P450 107G1 (RapN) 分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... 著者 Kim, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. 登録日 2019-10-10 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
6L8H	Crystal structure of CYP97C1 分子名称: Carotene epsilon-monooxygenase, chloroplastic, GLYCEROL, ... 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
4UQH	Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(3,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. 分子名称: (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(3,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE, ... 著者 Calvet, C.M, Vieira, D.F, Choi, J.Y, Cameron, M.D, Gut, J, Kellar, D, Siqueira-Neto, J.L, McKerrow, J.H, Roush, W.R, Podust, L.M. 登録日 2014-06-23 公開日 2014-08-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 4-Aminopyridyl-Based Cyp51 Inhibitors as Anti-Trypanosoma Cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency. J.Med.Chem., 57, 2014
6LDL	Crystal structure of CYP116B46-N(20-445) from Tepidiphilus thermophilus in complex with HEME 分子名称: BICINE, Cytochrome P450, GLYCEROL, ... 著者 Zhang, L.L, Xie, Z.Z, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2019-11-21 公開日 2020-10-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase. Nat Commun, 11, 2020
6L8J	Crystal structure of CYP97A3 mutant S290D/W300L/S304V in complex with retinal 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Protein LUTEIN DEFICIENT 5, chloroplastic, ... 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
6L1B	Crystal Structure of P450BM3 with N-(3-cyclopentylpropanoyl)-L-pipecolyl-L-phenylalanine 分子名称: (2S)-2-[[(2S)-1-(3-cyclopentylpropanoyl)piperidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, ... 著者 Shoji, O, Yonemura, K. 登録日 2019-09-28 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Systematic Evolution of Decoy Molecules for the Highly Efficient Hydroxylation of Benzene and Small Alkanes Catalyzed by Wild-Type Cytochrome P450BM3 Acs Catalysis, 10, 2020
6L69	Crystal structure of CYP154C2 from Streptomyces avermitilis 分子名称: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Xu, L.H, Fushinobu, S. 登録日 2019-10-28 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis. Biochem.Biophys.Res.Commun., 522, 2020
4WPZ	Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis 分子名称: Cytochrome P450, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Kang, L.W, Kim, D.H, Pham, T.V, Han, S.H. 登録日 2014-10-21 公開日 2015-04-22 最終更新日 2015-04-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch.Biochem.Biophys., 575, 2015
4WNT	Human Cytochrome P450 2D6 Ajmalicine Complex 分子名称: Ajmalicine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2014-10-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
6PRR	The crystal structure of 3-methylaminobenzoate-bound CYP199A4 分子名称: 3-(methylamino)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2019-07-11 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. J.Inorg.Biochem., 203, 2019
4WG2	P411BM3-CIS T438S I263F regioselective C-H amination catalyst 分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Hyster, T.K, Farwell, C.C, Buller, A.R, McIntosh, J.A, Arnold, F.H. 登録日 2014-09-17 公開日 2014-11-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-h amination. J.Am.Chem.Soc., 136, 2014
6PQ6	The crystal structure of 3-methoxybenzoate-bound CYP199A4 分子名称: 3-methoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G, Bruning, J.B. 登録日 2019-07-08 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.658 Å) 主引用文献 Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. J.Inorg.Biochem., 203, 2019
6PQS	The crystal structure of 4-methylbenzoate-bound CYP199A4 分子名称: 4-METHYLBENZOIC ACID, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2019-07-10 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. J.Inorg.Biochem., 203, 2019
6PRS	The crystal structure of 3-ethoxybenzoate-bound CYP199A4 分子名称: 3-ethoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2019-07-11 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.373 Å) 主引用文献 Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. J.Inorg.Biochem., 203, 2019
4WNW	Human Cytochrome P450 2D6 Thioridazine Complex 分子名称: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Cytochrome P450 2D6, NICKEL (II) ION, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2014-10-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.299 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
6PQD	The crystal structure of 3-methylthiobenzoate-bound CYP199A4 分子名称: 3-(methylsulfanyl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2019-07-09 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. J.Inorg.Biochem., 203, 2019
6PQW	The crystal structure of 3-methylbenzoate-bound CYP199A4 分子名称: 3-methylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2019-07-10 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.679 Å) 主引用文献 Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. J.Inorg.Biochem., 203, 2019
4WQ0	Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis in complex with Oligomycin A 分子名称: Cytochrome P450, Oligomycin A, PROTOPORPHYRIN IX CONTAINING FE 著者 Kang, L.W, Kim, D.H, Pham, T.V, Han, S.H. 登録日 2014-10-21 公開日 2015-10-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis in complex with Oligomycin A To Be Published
6M4Q	Cytochrome P450 monooxygenase StvP2 substrate-free structure 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. 登録日 2020-03-08 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
4WNV	Human Cytochrome P450 2D6 Quinine Complex 分子名称: Cytochrome P450 2D6, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2014-10-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015

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