5B26
| Crystal structure of mouse SEL1L | 分子名称: | Protein sel-1 homolog 1 | 著者 | Jeong, H, Lee, C. | 登録日 | 2016-01-09 | 公開日 | 2016-04-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway Sci Rep, 6, 2016
|
|
1LGR
| |
5DBU
| |
5DBT
| |
3V3V
| Structural and functional analysis of quercetagetin, a natural JNK1 inhibitor | 分子名称: | 3,5,6,7-TETRAHYDROXY-2-(3,4-DIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, C-Jun-amino-terminal kinase-interacting protein 1, CHLORIDE ION, ... | 著者 | Baek, S, Kang, N.J, Popowicz, G.M, Arciniega, M, Jung, S.K, Byun, S, Song, N.R, Heo, Y.S, Kim, B.Y, Lee, H.J, Holak, T.A, Augustin, M, Bode, A.M, Huber, R, Dong, Z, Lee, K.W. | 登録日 | 2011-12-14 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Functional Analysis of the Natural JNK1 Inhibitor Quercetagetin. J.Mol.Biol., 425, 2013
|
|
6IB2
| The structure of MKK7 in complex with the covalent 4-amino-pyrazolopyrimidine 4a | 分子名称: | 1-[(3~{R})-3-[4-azanyl-3-[1-(4-ethanoylphenyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 | 著者 | Wolle, P, Hardick, J, Mueller, M.P, Rauh, D. | 登録日 | 2018-11-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors. J.Med.Chem., 62, 2019
|
|
6IB0
| The structure of MKK7 in complex with the covalent 4-amino-pyrazolopyrimidine 3a | 分子名称: | 1-[(3~{R})-3-(4-azanyl-3-ethynyl-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]prop-2-en-1-one, Dual specificity mitogen-activated protein kinase kinase 7, TETRAETHYLENE GLYCOL | 著者 | Wolle, P, Hardick, J, Mueller, M.P, Rauh, D. | 登録日 | 2018-11-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors. J.Med.Chem., 62, 2019
|
|
5H62
| Structure of Transferase mutant-C23S,C199S | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, Transferase, ... | 著者 | Park, J.B, Yoo, Y, Kim, J. | 登録日 | 2016-11-10 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. Nat Commun, 9, 2018
|
|
5H5Y
| |
5H63
| Structure of Transferase mutant-C23S,C199S | 分子名称: | MANGANESE (II) ION, Transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | 著者 | Park, J.B, Yoo, Y, Kim, J. | 登録日 | 2016-11-10 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. Nat Commun, 9, 2018
|
|
5H60
| Structure of Transferase mutant-C23S,C199S | 分子名称: | MANGANESE (II) ION, Transferase, URIDINE-5'-DIPHOSPHATE | 著者 | Park, J.B, Yoo, Y, Kim, J. | 登録日 | 2016-11-10 | 公開日 | 2017-12-20 | 最終更新日 | 2018-10-31 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. Nat Commun, 9, 2018
|
|
5H61
| |
3CMJ
| |
3EIO
| Crystal Structure Analysis of DPPIV Inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-({4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,4-diazepan-1-yl}carbonyl)benzoic acid, ... | 著者 | Ahn, J.H, Lee, J.-O. | 登録日 | 2008-09-17 | 公開日 | 2008-11-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors Bioorg.Med.Chem.Lett., 18, 2008
|
|
2OLE
| Crystal Structure Of Human Dipeptidyl Peptidase IV (DPPIV) Complex With Cyclic Hydrazine Derivatives | 分子名称: | (2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE, Dipeptidyl peptidase 4 | 著者 | Kim, S.S, Ahn, J.H, Lee, J.O. | 登録日 | 2007-01-19 | 公開日 | 2008-01-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors Bioorg.Med.Chem.Lett., 17, 2007
|
|
6J10
| Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | 分子名称: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | 著者 | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | 登録日 | 2018-12-27 | 公開日 | 2019-04-17 | 最終更新日 | 2019-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun, 10, 2019
|
|
6I0C
| Human butyrylcholinesterase in complex with the R enantiomer of a chlorotacrine-tryptophan multi-target inhibitor. | 分子名称: | (2~{R})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brazzolotto, X, Nachon, F. | 登録日 | 2018-10-25 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.675 Å) | 主引用文献 | Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease. Eur.J.Med.Chem., 168, 2019
|
|
6K1D
| |
6K1C
| |
6K18
| Crystal structure of EXD2 exonuclease domain soaked in Mn | 分子名称: | Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION | 著者 | Park, J, Lee, C. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
|
|
6K1A
| Crystal structure of EXD2 exonuclease domain soaked in Mn and Mg | 分子名称: | Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION, MANGANESE (II) ION | 著者 | Park, J, Lee, C. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
|
|
6K19
| Crystal structure of EXD2 exonuclease domain soaked in Mg | 分子名称: | Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION | 著者 | Park, J, Lee, C. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
|
|
6KBM
| Crystal structure of Vac8 bound to Atg13 | 分子名称: | Autophagy-related protein 13, Vacuolar protein 8 | 著者 | Park, J, Lee, C. | 登録日 | 2019-06-25 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | 主引用文献 | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways. Autophagy, 16, 2020
|
|
6K17
| Crystal structure of EXD2 exonuclease domain | 分子名称: | Exonuclease 3'-5' domain-containing protein 2, SODIUM ION | 著者 | Park, J, Lee, C. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
|
|
6K1E
| |