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8S9N
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DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - C2 crystal form
分子名称: 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2023-03-29
公開日2023-08-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.
J.Biol.Chem., 299, 2023
8S9O
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DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - P1 crystal form
分子名称: 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN
著者Zhou, J, Horton, J.R, Cheng, X.
登録日2023-03-29
公開日2023-08-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.
J.Biol.Chem., 299, 2023
5A9I
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Crystal structure of the extracellular domain of PepT2
分子名称: CITRIC ACID, GLYCEROL, SOLUTE CARRIER FAMILY 15 MEMBER 2
著者Beale, J.H, Newstead, S.
登録日2015-07-21
公開日2015-09-09
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
5XIM
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PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
分子名称: D-XYLOSE ISOMERASE, MAGNESIUM ION, sorbitol
著者Janin, J.
登録日1992-03-30
公開日1993-07-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
5XWY
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Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
分子名称: A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER)
著者Zhang, X, Wang, Y, Ma, J, Liu, L, Li, X, Li, Z, You, L, Wang, J, Wang, M.
登録日2017-06-30
公開日2017-09-13
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
5XM1
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The mouse nucleosome structure containing H2A, H2B type3-A, H3mm7, and H4
分子名称: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
著者Taguchi, H, Horikoshi, N, Kurumizaka, H.
登録日2017-05-12
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nat Commun, 9, 2018
7Q3E
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Structure of the mouse CPLANE-RSG1 complex
分子名称: Ciliogenesis and planar polarity effector 2, GUANOSINE-5'-TRIPHOSPHATE, Protein fuzzy homolog, ...
著者Langousis, G, Cavadini, S, Kempf, G, Matthias, P.
登録日2021-10-27
公開日2022-04-06
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structure of the ciliogenesis-associated CPLANE complex.
Sci Adv, 8, 2022
5XME
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Solution structure of C-terminal domain of TRADD
分子名称: Tumor necrosis factor receptor type 1-associated DEATH domain protein
著者Lin, Z, Zhang, N.
登録日2017-05-15
公開日2017-09-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily.
Sci Rep, 7, 2017
3LWN
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Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex B)
分子名称: GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ...
著者Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W.
登録日2010-02-24
公開日2010-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
3LXR
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Shigella IpgB2 in complex with human RhoA and GDP (complex C)
分子名称: GUANOSINE-5'-DIPHOSPHATE, IpgB2, SULFATE ION, ...
著者Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W.
登録日2010-02-25
公開日2010-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry
J.Biol.Chem., 285, 2010
1KIX
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Dimeric Structure of the O. nova Telomere End Binding Protein Alpha Subunit with Bound ssDNA
分子名称: 5'-D(*T*TP*TP*TP*GP*GP*GP*G)-3', SULFATE ION, Telomere-Binding Protein alpha Subunit
著者Peersen, O.B, Ruggles, J.A, Schultz, S.C.
登録日2001-12-03
公開日2002-02-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA.
Nat.Struct.Biol., 9, 2002
5XW3
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Crystal structure of cystathionine beta-synthase from Bacillus anthracis
分子名称: O-acetylserine lyase
著者Devi, S, Tarique, K.F, Abdul Rehman, S.A, Gourinath, S.
登録日2017-06-29
公開日2017-08-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural characterization and functional analysis of cystathionine beta-synthase: an enzyme involved in the reverse transsulfuration pathway of Bacillus anthracis.
FEBS J., 284, 2017
8BAO
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Dysgonamonadaceae bacterium CRISPR ancillary nuclease 2
分子名称: BROMIDE ION, Cyclic tetra-adenylate (cA4), DUF1887 family protein, ...
著者Li, A.W.H, Doherty, A.J.
登録日2022-10-11
公開日2022-11-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
8B4A
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Nativ complex of PqsE and RhlR with autoinducer C4-HSL
分子名称: 2-aminobenzoylacetyl-CoA thioesterase, FE (III) ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, ...
著者Borgert, S.R, Blankenfeldt, W.
登録日2022-09-20
公開日2022-12-14
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Nat Commun, 13, 2022
3K5C
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BU of 3k5c by Molmil
Human BACE-1 complex with NB-216
分子名称: (4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phenyl]cyclopropyl}amino)ethyl]-19-(methoxymethyl)-11-oxa-3,16-diazatricyclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one, Beta-secretase 1
著者Rondeau, J.-M.
登録日2009-10-07
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application.
Bioorg.Med.Chem.Lett., 20, 2010
5DGO
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BU of 5dgo by Molmil
Crystal structure of cell division cycle protein 45 (Cdc45)
分子名称: 1,2-ETHANEDIOL, Cell division control protein 45 homolog, SULFATE ION
著者Simon, A.C, Pellegrini, L.
登録日2015-08-28
公開日2016-05-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of human Cdc45 and implications for CMG helicase function.
Nat Commun, 7, 2016
2JXR
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BU of 2jxr by Molmil
STRUCTURE OF YEAST PROTEINASE A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide, PROTEINASE A, ...
著者Aguilar, C.F, Badasso, M, Dreyer, T, Cronin, N.B, Newman, M.P, Cooper, J.B, Hoover, D.J, Wood, S.P, Johnson, M.S, Blundell, T.L.
登録日1997-04-24
公開日1997-10-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae.
J.Mol.Biol., 267, 1997
1H8C
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UBX domain from human faf1
分子名称: FAS-ASSOCIATED FACTOR 1
著者Bycroft, M.M.
登録日2001-02-01
公開日2001-02-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Ubx Domain: A Widespread Ubiquitin-Like Module
J.Mol.Biol., 307, 2001
4Z4F
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BU of 4z4f by Molmil
Human Argonaute2 Bound to t1-DAP Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4D
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BU of 4z4d by Molmil
Human Argonaute2 Bound to t1-G Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
5Y1Z
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BU of 5y1z by Molmil
Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain
分子名称: Drebrin, GLYCEROL, Protein kinase C-binding protein 1, ...
著者Yao, N, Li, J, Liu, H, Wan, J, Liu, W, Zhang, M.
登録日2017-07-22
公開日2017-10-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.676 Å)
主引用文献The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin
Structure, 25, 2017
3K2H
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BU of 3k2h by Molmil
Co-crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis with dUMP, Pemetrexed and NADP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-09-30
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis.
Acta Crystallogr.,Sect.F, 67, 2011
6QUM
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Thermus thermophilus V/A-type ATPase/synthase, rotational state 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, V-type ATP synthase alpha chain, ...
著者Zhou, L, Sazanov, L.
登録日2019-02-27
公開日2019-08-28
最終更新日2020-09-30
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase.
Science, 365, 2019
8PWH
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Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, Pertuzumab Fab light chain, ...
著者Ruedas, R, Vuillemot, R, Tubiana, T, Winter, J.M, Pieri, L, Arteni, A.A, Samson, C, Jonic, J, Mathieu, M, Bressanelli, S.
登録日2023-07-20
公開日2024-02-21
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex.
J.Struct.Biol., 216, 2024
4Z4C
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Human Argonaute2 Bound to t1-C Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015

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