PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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7O5O	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-165 分子名称: 14-3-3 protein sigma, 4-methanoyl-~{N}-[(1-methylpyrazol-4-yl)methyl]benzamide, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-09 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O5X	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-173 分子名称: 14-3-3 protein sigma, 4-(4-methoxypiperidin-1-yl)carbonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-09 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O3Q	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-041 分子名称: 14-3-3 protein sigma, 4-methyl-~{N}-(1-methylpyrazol-3-yl)benzenesulfonamide, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-02 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6I	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-085 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-11 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O5A	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-158 分子名称: 14-3-3 protein sigma, 4-(3-methoxyazetidin-1-yl)carbonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-08 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6O	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-096 分子名称: (5-methanoyl-2-nitro-phenyl) propane-2-sulfonate, 14-3-3 protein sigma, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-11 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O6G	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-176 分子名称: 14-3-3 protein sigma, 4-[(3~{R})-3-oxidanylpiperidin-1-yl]carbonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-11 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O24	Structure of the foamy viral protease-reverse transcriptase in complex with dsDNA. 分子名称: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*CP*CP*TP*GP*AP*TP*TP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol 著者 Nowotny, M, Czarnocki-Cieciura, M. 登録日 2021-03-30 公開日 2021-06-30 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase. J.Virol., 95, 2021
7O0H	Structure of the foamy viral protease-reverse transcriptase dRH in complex with ds DNA. 分子名称: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol 著者 Nowak, E, Nowacka, M, Nowotny, M. 登録日 2021-03-26 公開日 2021-06-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase. J.Virol., 95, 2021
7O0G	Structure of the foamy viral protease-reverse transcriptase in complex with RNA/DNA hybrid. 分子名称: DNA (5'-D(*CP*CP*TP*CP*TP*CP*CP*TP*GP*GP*AP*CP*AP*AP*G)-3'), Pr125Pol, RNA (5'-R(*UP*UP*CP*UP*UP*GP*UP*CP*CP*AP*GP*GP*AP*GP*AP*GP*G)-3') 著者 Nowak, E, Nowacka, M, Nowotny, M. 登録日 2021-03-26 公開日 2021-06-30 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase. J.Virol., 95, 2021
7O31	Crystal structure of the anti-PAS Fab 1.2 in complex with its epitope peptide and the anti-Kappa VHH domain 分子名称: 1,2-ETHANEDIOL, PAS#1 epitope peptide, anti-Kappa VHH domain, ... 著者 Schilz, J, Schiefner, A, Skerra, A. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021
4HEA	Crystal structure of the entire respiratory complex I from Thermus thermophilus 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... 著者 Baradaran, R, Berrisford, J.M, Minhas, G.S, Sazanov, L.A. 登録日 2012-10-03 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3027 Å) 主引用文献 Crystal structure of the entire respiratory complex I. Nature, 494, 2013
7O30	Crystal structure of the anti-PAS Fab 1.1 in complex with its epitope peptide 分子名称: PAS#1 epitope peptide, anti-PAS Fab 1.1 chimeric heavy chain, anti-PAS Fab 1.1 chimeric light chain 著者 Schilz, J, Schiefner, A, Skerra, A. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021
7O2Z	Crystal structure of the anti-PAS Fab 2.2 in complex with its epitope peptide 分子名称: CHLORIDE ION, P/A#1 epitope peptide, anti-PAS Fab 2.2 chimeric heavy chain, ... 著者 Schilz, J, Schiefner, A, Skerra, A. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021
7O33	Crystal structure of the anti-PAS Fab 3.1 in complex with its epitope peptide 分子名称: APSA epitope peptide, anti-PAS Fab 3.1 chimeric heavy chain, anti-PAS Fab 3.1 chimeric light chain 著者 Schilz, J, Skerra, A. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433, 2021
1S6Y	2.3A crystal structure of phospho-beta-glucosidase 分子名称: 6-phospho-beta-glucosidase 著者 Tereshko, V, Dementieva, I, Kim, Y, Collat, F, Joachimiak, A, Kossiakoff, A, Midwest Center for Structural Genomics (MCSG) 登録日 2004-01-28 公開日 2004-05-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 2.3A CRYSTAL STRUCTURE OF PHOSPHO-BETA-GLUCOSIDASE, licH Gene Product from BACILLUS STEAROTHERMOPHILUS To be Published
3NC7	CYP134A1 2-phenylimidazole bound structure 分子名称: 2-phenyl-1H-imidazole, Cytochrome P450 cypX, MAGNESIUM ION, ... 著者 Cryle, M.J, Schlichting, I. 登録日 2010-06-04 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
3NH8	Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine 分子名称: Aspartoacylase-2, CHLORIDE ION, N-acetyl-S-[(1S)-1,2-dichloroethyl]-L-cysteine, ... 著者 Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A. 登録日 2010-06-14 公開日 2010-10-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Structures of aminoacylase 3 in complex with acetylated substrates. Proc.Natl.Acad.Sci.USA, 107, 2010
3NH4	Crystal structure of murine aminoacylase 3 分子名称: ACETATE ION, Aspartoacylase-2, CESIUM ION, ... 著者 Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A. 登録日 2010-06-14 公開日 2010-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of aminoacylase 3 in complex with acetylated substrates. Proc.Natl.Acad.Sci.USA, 107, 2010
3NC3	CYP134A1 structure with a closed substrate binding loop 分子名称: Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ... 著者 Cryle, M.J, Schlichting, I. 登録日 2010-06-04 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
7MFE	Autoinhibited BRAF:(14-3-3)2 complex with the BRAF RBD resolved 分子名称: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf, ZINC ION 著者 Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K. 登録日 2021-04-09 公開日 2022-01-26 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding. Nat Commun, 13, 2022
1RJP	Crystal structure of D-aminoacylase in complex with 100mM CuCl2 分子名称: ACETATE ION, COPPER (II) ION, D-aminoacylase, ... 著者 Lai, W.L, Chou, L.Y, Ting, C.Y, Tsai, Y.C, Liaw, S.H. 登録日 2003-11-20 公開日 2004-04-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation. J.Biol.Chem., 279, 2004
7MFD	Autoinhibited BRAF:(14-3-3)2:MEK complex with the BRAF RBD resolved 分子名称: 14-3-3 protein zeta/delta, Dual specificity mitogen-activated protein kinase kinase 1, N-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2H-chromen-3-yl]methyl}pyridin-2-yl)-N'-methylsulfuric diamide, ... 著者 Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K. 登録日 2021-04-09 公開日 2022-01-26 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding. Nat Commun, 13, 2022
3T3R	Human Cytochrome P450 2A6 in complex with Pilocarpine 分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE 著者 DeVore, N.M, Scott, E.E. 登録日 2011-07-25 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
3TDA	Competitive replacement of thioridazine by prinomastat in crystals of cytochrome P450 2D6 分子名称: Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, Prinomastat, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2011-08-10 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015

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