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7MI5
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Asymmetrical PAM-Non PAM prespacer bound Cas4/Cas1/Cas2 complex
分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (26-MER), ...
著者Hu, C.Y, Ke, A.K.
登録日2021-04-16
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
2EXF
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BU of 2exf by Molmil
Solution structure of the HIV-1 nucleocapsid (NCp7(12-55)) complexed with the DNA (-) Primer Binding Site
分子名称: 5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*C)-3', Nucleocapsid protein* (NC*), ZINC ION
著者Bourbigot, S, Bouaziz, S, Morellet, N.
登録日2005-11-08
公開日2007-04-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.
J.Mol.Biol., 383, 2008
2MHX
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Structure of Exocyclic R,R N6,N6-(2,3-Dihydroxy-1,4-butadiyl)-2'-Deoxyadenosine Adduct Induced by 1,2,3,4-Diepoxybutane in DNA
分子名称: 5'-D(*CP*GP*GP*AP*CP*(RBD)P*AP*GP*AP*AP*G)-3'), 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3')
著者Kowal, E.A, Seneviratne, U, Wickramaratne, S, Doherty, K.E, Cao, X, Tretyakova, N, Stone, M.P.
登録日2013-12-05
公開日2014-05-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures of Exocyclic R,R- and S,S-N(6),N(6)-(2,3-Dihydroxybutan-1,4-diyl)-2'-Deoxyadenosine Adducts Induced by 1,2,3,4-Diepoxybutane.
Chem.Res.Toxicol., 27, 2014
4Z2C
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BU of 4z2c by Molmil
Quinolone(Moxifloxacin)-DNA cleavage complex of gyrase from S. pneumoniae
分子名称: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ...
著者Laponogov, I, Veselkov, D.A, Pan, X.-S, Selvarajah, J, Crevel, I.M.-T, Fisher, L.M, Sanderson, M.R.
登録日2015-03-29
公開日2016-09-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structural studies of the drug-stabilized cleavage complexes of topoisomerase IV and gyrase from Streptococcus pneumoniae
To Be Published
4Z2D
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Quinolone(Levofloxacin)-DNA cleavage complex of gyrase from S. pneumoniae
分子名称: (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ...
著者Laponogov, I, Veselkov, D.A, Pan, X.-S, Selvarajah, J, Crevel, I.M.-T, Fisher, L.M, Sanderson, M.R.
登録日2015-03-29
公開日2016-09-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Structural studies of the drug-stabilized cleavage complexes of topoisomerase IV and gyrase from Streptococcus pneumoniae
To Be Published
4MDF
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BU of 4mdf by Molmil
Structure of bacterial polynucleotide kinase Michaelis complex bound to GTP and DNA
分子名称: CITRIC ACID, DNA (5'-D(*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, ...
著者Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A.
登録日2013-08-22
公開日2013-11-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.727 Å)
主引用文献Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition.
Nucleic Acids Res., 42, 2014
1WRT
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BU of 1wrt by Molmil
NMR STUDY OF APO TRP REPRESSOR
分子名称: APO TRP REPRESSOR
著者Zhao, D, Zheng, Z.
登録日1995-05-12
公開日1996-06-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1WRS
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NMR STUDY OF HOLO TRP REPRESSOR
分子名称: HOLO TRP REPRESSOR, TRYPTOPHAN
著者Zhao, D, Zheng, Z.
登録日1995-05-12
公開日1996-06-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
8C8J
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BU of 8c8j by Molmil
Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, ...
著者Nichols, C.E, Walpole, T.B, Baldwin, E.
登録日2023-01-20
公開日2023-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
2C6R
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BU of 2c6r by Molmil
FE-SOAKED CRYSTAL STRUCTURE OF THE DPS92 FROM DEINOCOCCUS RADIODURANS
分子名称: CHLORIDE ION, DNA-BINDING STRESS RESPONSE PROTEIN, DPS FAMILY, ...
著者Cuypers, M.G, Romao, C.V, Mitchell, E, Mcsweeney, S.
登録日2005-11-11
公開日2007-02-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of the Dps2 from Deinococcus Radiodurans Reveals an Unusual Pore Profile with a Non-Specific Metal Binding Site.
J.Mol.Biol., 371, 2007
6V2K
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BU of 6v2k by Molmil
The nucleosome structure after H2A-H2B exchange
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
著者Arimura, Y, Hirano, R, Kurumizaka, H.
登録日2019-11-24
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome.
Commun Biol, 4, 2021
7N10
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BU of 7n10 by Molmil
Co-crystal structure of Prx with ComR DNA binding domain
分子名称: ComR, Prx
著者Rutbeek, N.R, Prehna, G.
登録日2021-05-26
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox.
J.Biol.Chem., 297, 2021
2ZTE
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BU of 2zte by Molmil
MtRuvA Form IV
分子名称: Holliday junction ATP-dependent DNA helicase ruvA
著者Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M.
登録日2008-10-01
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability
Biochim.Biophys.Acta, 1794, 2009
6YSZ
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BU of 6ysz by Molmil
Cryo-EM structure of T7 bacteriophage DNA translocation gp15 core protein intermediate assembly
分子名称: Internal virion protein gp15
著者Perez-Ruiz, M, Pulido-Cid, M, Luque-Ortega, J.R, Cuervo, A, Carrascosa, J.L.
登録日2020-04-23
公開日2021-09-08
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Assisted assembly of bacteriophage T7 core components for genome translocation across the bacterial envelope.
Proc.Natl.Acad.Sci.USA, 118, 2021
6YT5
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BU of 6yt5 by Molmil
Cryo-EM structure of T7 bacteriophage DNA translocation gp15-gp16 core complex intermediate assembly
分子名称: Internal virion protein gp15, Peptidoglycan transglycosylase gp16
著者Perez-Ruiz, M, Pulido-Cid, M, Luque-Ortega, J.R, Cuervo, A, Carrascosa, J.L.
登録日2020-04-23
公開日2021-09-08
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Assisted assembly of bacteriophage T7 core components for genome translocation across the bacterial envelope.
Proc.Natl.Acad.Sci.USA, 118, 2021
2ZTC
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BU of 2ztc by Molmil
MtRuvA Form II
分子名称: GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA
著者Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M.
登録日2008-10-01
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability
Biochim.Biophys.Acta, 1794, 2009
2ZTD
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BU of 2ztd by Molmil
MtRuvA Form III
分子名称: GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA
著者Prabu, J.R, Thamotharan, S, Khanduja, J.S, Chandra, N.R, Muniyappa, K, Vijayan, M.
登録日2008-10-01
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA Additional role of RuvB-binding domain and inter species variability
Biochim.Biophys.Acta, 1794, 2009
1AK0
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BU of 1ak0 by Molmil
P1 NUCLEASE IN COMPLEX WITH A SUBSTRATE ANALOG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-(DITHIO)PHOSPHATE, ...
著者Romier, C, Suck, D.
登録日1997-05-28
公開日1997-12-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recognition of single-stranded DNA by nuclease P1: high resolution crystal structures of complexes with substrate analogs.
Proteins, 32, 1998
1ENJ
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BU of 1enj by Molmil
CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS
分子名称: ENDONUCLEASE V
著者Vassylyev, D.G, Ariyoshi, M, Matsumoto, O, Katayanagi, K, Ohtsuka, E, Morikawa, K.
登録日1994-08-08
公開日1994-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
6B8A
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BU of 6b8a by Molmil
Crystal structure of MvfR ligand binding domain in complex with M64
分子名称: 2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide, COBALT HEXAMMINE(III), DNA-binding transcriptional regulator
著者Kitao, T, Steinbacher, S, Maskos, K, Blaesse, M, Rahme, L.G.
登録日2017-10-05
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular Insights into Function and Competitive Inhibition ofPseudomonas aeruginosaMultiple Virulence Factor Regulator.
MBio, 9, 2018
4QH0
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BU of 4qh0 by Molmil
Crystal structure of NucA from Streptococcus agalactiae with magnesium ion bound
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA-entry nuclease (Competence-specific nuclease), ...
著者Moon, A.F, Gaudu, P, Pedersen, L.C.
登録日2014-05-26
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of the virulence factor nuclease A from Streptococcus agalactiae.
Acta Crystallogr.,Sect.D, 70, 2014
7EI5
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GNRA tetraloop receptor motif composed of RNA and DNA
分子名称: COBALT (II) ION, DNA/RNA (35-MER), STRONTIUM ION
著者Kondo, J, Hayasaka, A.
登録日2021-03-30
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献RNA GNRA tetraloop and tetraloop receptor motifs
To Be Published
6IYA
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BU of 6iya by Molmil
Structure of the DNA binding domain of antitoxin CopASO
分子名称: Transcriptional regulator CopG family
著者Zhao, R, Li, F, Liu, L, Zhang, X.
登録日2018-12-14
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and allosteric coupling of type II antitoxin CopASO.
Biochem.Biophys.Res.Commun., 514, 2019
1DSD
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BU of 1dsd by Molmil
NMR STUDY OF DNA (5'-D(*GP*AP*TP*GP*CP*TP*TP*C)-3') T:T MISMATCHED DUPLEX COMPLEXED WITH ACTINOMYCIN D, MINIMIZED AVERAGE STRUCTURE
分子名称: ACTINOMYCIN D, DNA (5'-D(*GP*AP*TP*GP*CP*TP*TP*C)-3')
著者Lian, C, Robinson, H, Wang, A.H.-J.
登録日1996-08-10
公開日1996-12-07
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structure of Actinomycin D Bound with (Gaagcttc)2 and (Gatgcttc)2 and its Binding to the (Cag)N:(Ctg)N Triplet Sequence by NMR Analysis
J.Am.Chem.Soc., 118, 1996
1DSC
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BU of 1dsc by Molmil
NMR STUDY OF DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') SELF-COMPLEMENTARY DUPLEX COMPLEXED WITH ACTINOMYCIN D, MINIMIZED AVERAGE STRUCTURE
分子名称: ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3')
著者Lian, C, Robinson, H, Wang, A.H.-J.
登録日1996-08-10
公開日1996-12-07
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structure of Actinomycin D Bound with (Gaagcttc)2 and (Gatgcttc)2 and its Binding to the (Cag)N:(Ctg)N Triplet Sequence by NMR Analysis
J.Am.Chem.Soc., 118, 1996

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