8T3W
| Structure of Bre1-nucleosome complex - state2 | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | 登録日 | 2023-06-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T3T
| Structure of Bre1-nucleosome complex - state3 | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | 登録日 | 2023-06-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T3Y
| Structure of Bre1-nucleosome complex - state1 | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ... | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | 登録日 | 2023-06-08 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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3OSF
| The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-2f-13 DNA | 分子名称: | 5'-D(*CP*AP*AP*GP*AP*CP*GP*AP*TP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*AP*TP*CP*GP*TP*CP*TP*TP*G)-3', ISOPROPYL ALCOHOL, ... | 著者 | Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H. | 登録日 | 2010-09-09 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 39, 2011
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4BE2
| PFV intasome with inhibitor XZ-259 | 分子名称: | 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND) *AP*CP*A)-3', 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 2-(3-chloro-4-fluorobenzyl)-6,7-dihydroxy-N,N-dimethyl-1-oxo-2,3-dihydro-1H-isoindole-4-sulfonamide, ... | 著者 | Hare, S, Cherepanov, P. | 登録日 | 2012-10-08 | 公開日 | 2012-10-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Activities, Crystal Structures and Molecular Dynamics of Dihydro-1H-Isoindole Derivatives, Inhibitors of HIV-1 Integrase. Acs Chem.Biol., 8, 2013
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6QM2
| NlaIV restriction endonuclease | 分子名称: | POTASSIUM ION, SODIUM ION, Type-2 restriction enzyme NlaIV | 著者 | Czapinska, H, Siwek, W, Szczepanowski, R.H, Bujnicki, J.M, Bochtler, M, Skowronek, K. | 登録日 | 2019-02-01 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease. J.Mol.Biol., 431, 2019
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7ODF
| Structure of the mini-RNA-guided endonuclease CRISPR-Cas_phi3 | 分子名称: | Cas_phi3, DNA (5'-D(P*GP*G)-3'), DNA (5'-D(P*GP*TP*AP*AP*TP*TP*CP*AP*G)-3'), ... | 著者 | Carabias del Rey, A, Fugilsang, A, Temperini, P, Pape, T, Sofos, N, Stella, S, Erledsson, S, Montoya, G. | 登録日 | 2021-04-29 | 公開日 | 2021-07-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3. Nat Commun, 12, 2021
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6TYD
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1LPV
| DROSOPHILA MELANOGASTER DOUBLESEX (DSX), NMR, 18 STRUCTURES | 分子名称: | Doublesex protein, ZINC ION | 著者 | Zhu, L, Wilken, J, Phillips, N, Narendra, U, Chan, G, Stratton, S, Kent, S, Weiss, M.A. | 登録日 | 2002-05-08 | 公開日 | 2002-10-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers. Genes Dev., 14, 2000
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4HQX
| CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A Modified nucleotide aptamer (SOMAmer SL4) | 分子名称: | MAGNESIUM ION, Platelet-derived growth factor subunit B, SODIUM ION, ... | 著者 | Davies, D.R, Edwards, T.E, Janjic, N, Gelinas, A.D, Zhang, C, Jarvis, T.C. | 登録日 | 2012-10-26 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proc.Natl.Acad.Sci.USA, 109, 2012
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1F2R
| NMR STRUCTURE OF THE HETERODIMERIC COMPLEX BETWEEN CAD DOMAINS OF CAD AND ICAD | 分子名称: | CASPASE-ACTIVATED DNASE, INHIBITOR OF CASPASE-ACTIVATED DNASE | 著者 | Otomo, T, Sakahira, H, Uegaki, K, Nagata, S, Yamazaki, T. | 登録日 | 2000-05-29 | 公開日 | 2000-06-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the heterodimeric complex between CAD domains of CAD and ICAD. Nat.Struct.Biol., 7, 2000
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2KQX
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4BDZ
| PFV intasome with inhibitor XZ-90 | 分子名称: | 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND), 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 2-[(3-chloranyl-4-fluoranyl-phenyl)methyl]-6,7-bis(oxidanyl)isoindol-1-one, ... | 著者 | Hare, S, Cherepanov, P. | 登録日 | 2012-10-08 | 公開日 | 2012-10-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Activities, Crystal Structures and Molecular Dynamics of Dihydro-1H-Isoindole Derivatives, Inhibitors of HIV-1 Integrase. Acs Chem.Biol., 8, 2013
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8QWF
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4OVF
| E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid | 分子名称: | (2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2014-02-21 | 公開日 | 2014-03-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
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4OVH
| E. coli sliding clamp in complex with (R)-6-bromo-9-(2-(carboxymethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid | 分子名称: | (2R)-6-bromo-9-{2-[(carboxymethyl)amino]-2-oxoethyl}-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2014-02-21 | 公開日 | 2014-03-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
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5GT3
| Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-D, ... | 著者 | Kumarevel, T, Sivaraman, P. | 登録日 | 2016-08-18 | 公開日 | 2017-02-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b Biophys. Chem., 221, 2017
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4YM6
| Crystal structure of the human nucleosome containing 6-4PP (outside) | 分子名称: | 145-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H. | 登録日 | 2015-03-06 | 公開日 | 2015-12-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.514 Å) | 主引用文献 | Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome Sci Rep, 5, 2015
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7NVV
| XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, General transcription and DNA repair factor IIH helicase subunit XPB, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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5D49
| Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination | 分子名称: | ACETATE ION, DNA (5'-D(*AP*AP*AP*AP*A)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), ... | 著者 | Loc'h, J, Rosario, S, Delarue, M. | 登録日 | 2015-08-07 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination. Structure, 24, 2016
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4PNW
| E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((S)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid | 分子名称: | (2R)-6-bromo-9-(2-{[(1S)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2014-02-21 | 公開日 | 2014-03-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
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2GIE
| HincII bound to cognate DNA GTTAAC | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*G)-3', SODIUM ION, Type II restriction enzyme HincII | 著者 | Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J. | 登録日 | 2006-03-28 | 公開日 | 2006-07-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism. J.Biol.Chem., 281, 2006
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185D
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4OVG
| E. coli sliding clamp in complex with (R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid | 分子名称: | (2R)-9-(2-amino-2-oxoethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2014-02-21 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
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4BE0
| PFV intasome with inhibitor XZ-115 | 分子名称: | 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND), 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 2-(3-chloro-2-fluorobenzyl)-4,5-dihydroxy-1H-isoindole-1,3(2H)-dione, ... | 著者 | Hare, S, Cherepanov, P. | 登録日 | 2012-10-08 | 公開日 | 2012-10-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Activities, Crystal Structures and Molecular Dynamics of Dihydro-1H-Isoindole Derivatives, Inhibitors of HIV-1 Integrase. Acs Chem.Biol., 8, 2013
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