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6D80
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BU of 6d80 by Molmil
Cryo-EM structure of the mitochondrial calcium uniporter from N. fischeri bound to saposin
分子名称: CALCIUM ION, Mitochondrial calcium uniporter, Saposin A
著者Nguyen, N.X, Armache, J.-P, Cheng, Y, Bai, X.C.
登録日2018-04-25
公開日2018-07-11
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
6D81
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BU of 6d81 by Molmil
Structure of the Bovine p85a BH domain
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D82
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BU of 6d82 by Molmil
Structure of the Bovine p85a BH domain
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D83
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BU of 6d83 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Buffalo, C.Z, Morris, K.L, Hurley, J.H.
登録日2018-04-25
公開日2018-08-08
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6D84
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BU of 6d84 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Buffalo, C.Z, Morris, K.L, Hurley, J.H.
登録日2018-04-25
公開日2018-08-08
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (6.72 Å)
主引用文献HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6D85
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BU of 6d85 by Molmil
Structure of the Bovine p85a BH domain E217K mutant
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D86
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BU of 6d86 by Molmil
Structure of the Bovine p85a BH domain
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D87
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BU of 6d87 by Molmil
Structure of the Bovine p85alpha BH domain, R262T mutant
分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
著者Moore, S.A, Marshall, J.D, Anderson, D.H.
登録日2018-04-25
公開日2018-05-23
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
6D88
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BU of 6d88 by Molmil
Tubulin-RB3_SLD-TTL in complex with compound 13f
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kumar, G, Wang, Y, Li, W, White, S.W.
登録日2018-04-26
公開日2018-09-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.853 Å)
主引用文献Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities.
J. Med. Chem., 61, 2018
6D89
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BU of 6d89 by Molmil
Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion
分子名称: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, CITRIC ACID
著者Walton, W.G, Pellock, S.J, Redinbo, M.R.
登録日2018-04-26
公開日2018-10-17
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8A
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BU of 6d8a by Molmil
RsAgo Ternary Complex with guide RNA and Target DNA Containing A-A Bulge Within the Seed Segment of the Target Strand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*AP*AP*TP*AP*AP*C)-3'), ...
著者Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
登録日2018-04-26
公開日2018-07-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D8B
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BU of 6d8b by Molmil
The crystal structure of hemagglutinin from A/Hong Kong/125/2017 H7N9 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Yang, H, Stevens, J.
登録日2018-04-26
公開日2018-05-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural and Molecular Characterization of the Hemagglutinin from the Fifth-Epidemic-Wave A(H7N9) Influenza Viruses.
J. Virol., 92, 2018
6D8C
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BU of 6d8c by Molmil
Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A.
登録日2018-04-26
公開日2018-09-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of the filamin A actin-binding domain interaction with F-actin.
Nat. Struct. Mol. Biol., 25, 2018
6D8D
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BU of 6d8d by Molmil
The crystal structure of hemagglutinin from A/Hong Kong/125/2017 influenza virus in complex with LSTb
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者Yang, H, Stevens, J.
登録日2018-04-26
公開日2018-05-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Structural and Molecular Characterization of the Hemagglutinin from the Fifth-Epidemic-Wave A(H7N9) Influenza Viruses.
J. Virol., 92, 2018
6D8E
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BU of 6d8e by Molmil
Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor
分子名称: (4-fluorophenyl)methyl {2-[(1-methyl-1H-pyrazol-3-yl)amino]pyrimidin-4-yl}[3-(propanoylamino)phenyl]carbamate, Epidermal growth factor receptor
著者Park, E, Eck, M.J.
登録日2018-04-26
公開日2018-07-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.537 Å)
主引用文献Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor.
Angew. Chem. Int. Ed. Engl., 57, 2018
6D8F
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BU of 6d8f by Molmil
RsAgo Ternary Complex with Guide RNA and Target DNA Containing T-T Bulge Within the Seed Segment
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*TP*TP*TP*AP*AP*C)-3'), ...
著者Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
登録日2018-04-26
公開日2018-07-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D8G
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BU of 6d8g by Molmil
D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2
分子名称: Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION
著者Walton, W.G, Pellock, S.J, Redinbo, M.R.
登録日2018-04-26
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8H
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BU of 6d8h by Molmil
NMR solution structure of tamapin, mutant Y31+N
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-26
公開日2019-05-01
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D8I
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BU of 6d8i by Molmil
Mycobacterium tuberculosis polyketide synthase 13 N-terminal acyl carrier protein domain
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Polyketide synthase, ...
著者Tang, S, Sacchettini, J.
登録日2018-04-26
公開日2018-06-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Mycobacterium tuberculosis polyketide synthase 13 N-terminal acyl carrier protein domain
To be Published
6D8J
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BU of 6d8j by Molmil
Mycobacterium tuberculosis polyketide synthase 13 N-terminal acyl carrier protein domain
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Polyketide synthase, ...
著者Tang, S, Sacchettini, J.
登録日2018-04-26
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Mycobacterium tuberculosis polyketide synthase 13 N-terminal acyl carrier protein domain
To be Published
6D8K
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BU of 6d8k by Molmil
Bacteroides multiple species beta-glucuronidase
分子名称: Glycosyl hydrolase family 2, sugar binding domain protein
著者Walton, W.G, Pellock, S.J, Redinbo, M.R.
登録日2018-04-26
公開日2018-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8L
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BU of 6d8l by Molmil
Group I self-splicing intron P4-P6 domain mutant U131A (without isopropanol soaking)
分子名称: Group I self-splicing intron, MAGNESIUM ION
著者Shoffner, G.M.
登録日2018-04-26
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1402154 Å)
主引用文献In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8M
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BU of 6d8m by Molmil
Group I self-splicing intron P4-P6 domain mutant A125U/G126U
分子名称: Group I self-splicing intron, MAGNESIUM ION
著者Shoffner, G.M.
登録日2018-04-26
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8N
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BU of 6d8n by Molmil
Group I self-splicing intron P4-P6 domain mutant G134A/U185AA
分子名称: Group I self-splicing intron, MAGNESIUM ION
著者Shoffner, G.M.
登録日2018-04-26
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.95427132 Å)
主引用文献In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6D8O
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BU of 6d8o by Molmil
Group I self-splicing intron P4-P6 domain mutant A230U
分子名称: Group I self-splicing intron, MAGNESIUM ION
著者Shoffner, G.M.
登録日2018-04-26
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.80112481 Å)
主引用文献In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018

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