PDB: 31171 件ウェブページステータス検索Chemie searchBIRD

---

5EH7	human carbonic anhydrase II in complex with ligand 分子名称: 5-[[3,4-bis(chloranyl)phenoxy]methyl]-1~{H}-1,2,3,4-tetrazole, Carbonic anhydrase 2, FORMIC ACID, ... 著者 Ren, B. 登録日 2015-10-28 公開日 2016-03-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.425 Å) 主引用文献 Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59, 2016
8BM2	Crystal structure of JAK2 JH1 in complex with gandotinib 分子名称: 3-[(4-chloranyl-2-fluoranyl-phenyl)methyl]-2-methyl-~{N}-(5-methyl-1~{H}-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine, Tyrosine-protein kinase JAK2 著者 Miao, Y, Haikarainen, T. 登録日 2022-11-10 公開日 2023-11-22 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity. J.Med.Chem., 67, 2024
7PR4	Cocrystal Form II of a cytochrome c, sulfonato-thiacalix[4]arene - zinc cluster 分子名称: Cytochrome c iso-1, HEME C, PHOSPHATE ION, ... 著者 Flood, R.J, Ramberg, K, Guagnini, F, Crowley, P.B. 登録日 2021-09-20 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Protein Frameworks with Thiacalixarene and Zinc. Cryst.Growth Des., 22, 2022
8BN2	Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with D-Serine 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Heroven, C, Malinauskas, T, Aricescu, A.R. 登録日 2022-11-11 公開日 2023-11-22 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 GluD1 binds GABA and controls inhibitory plasticity. Science, 382, 2023
8K7O	De novo design protein -T03 分子名称: De novo design protein 著者 Wang, S, Liu, Y. 登録日 2023-07-27 公開日 2024-07-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 De novo design protein -T03 To Be Published
7NFT	Fujian capbinding domain in complex with Nb8208 分子名称: Nb8208, Polymerase basic protein 2, SULFATE ION 著者 Keown, J.R, Grimes, J.M, Fodor, E. 登録日 2021-02-07 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
5EJ9	EcMenD-ThDP-Mn2+ complex soaked with 2-ketoglutarate for 2 min and isochorismate for 13 min 分子名称: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, FORMIC ACID, GLYCEROL, ... 著者 Song, H.G, Dong, C, Chen, Y.Z, Sun, Y.R, Guo, Z.H. 登録日 2015-11-01 公開日 2016-06-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis J.Am.Chem.Soc., 138, 2016
8BP4	Crystal structure of Trichoplax Scribble PDZ2 domain in complex with Trichoplax Vangl peptide 分子名称: AMMONIUM ION, Leucine-rich repeat-containing protein 1, SULFATE ION, ... 著者 Maddumage, J.C, Kvansakul, M. 登録日 2022-11-16 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structure of Trichoplax Scribble PDZ2 domain in complex with Trichoplax Vangl peptide To be published
8BP6	Structure of MHC-class I related molecule MR1 with bound M3Ade 分子名称: (1R,5S)-8-(9H-purin-6-yl)-2-oxa-8-azabicyclo[3.3.1]nona-3,6-diene-4,6-dicarbaldehyde, Beta-2-microglobulin,Major histocompatibility complex class I-related gene protein 著者 Berloffa, G, Jakob, R.P, Maier, T. 登録日 2022-11-16 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The carbonyl nucleoside adduct M3Ade stabilizes MR1 and activates MR1-restricted self- and tumor-reactive T cells To Be Published
7VCN	Crystal Structure of PitA fragment from pilus islet-2 of Streptococcus oralis with Tb-Xo4 分子名称: TERBIUM(III) ION, Tb-Xo4, von Willebrand factor type A domain protein 著者 Yadav, R.K, Krishnan, V. 登録日 2021-09-03 公開日 2022-07-13 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.343 Å) 主引用文献 New structural insights into the PI-2 pilus from Streptococcus oralis, an early dental plaque colonizer. Febs J., 289, 2022
5EI0	Structure of RCL-cleaved vaspin (serpinA12) 分子名称: Serpin A12 著者 Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N. 登録日 2015-10-29 公開日 2015-11-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of cleaved vaspin (serpinA12). Biol.Chem., 397, 2016
8BTT	Structure of human RTCB 分子名称: MANGANESE (II) ION, RNA-splicing ligase RtcB homolog 著者 Kopp, J, Gerber, J.L, Peschek, J. 登録日 2022-11-30 公開日 2023-12-13 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease. Nat Commun, 15, 2024
5VV7	Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-(((3-(PYRIDIN-3-YL)PROPYL)AMINO)METHYL)QUINOLIN-2-, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 2017-05-19 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem., 60, 2017
7Q0L	Crystal structure of the peptide transporter YePEPT-K314A at 2.93 A 分子名称: Peptide transporter YePEPT 著者 Jeckelmann, J.M, Stauffer, M, Ilgue, H, Boggavarapu, R, Fotiadis, D. 登録日 2021-10-15 公開日 2022-03-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5, 2022
5KLE	Structure of CBM_E1, a novel carbohydrate-binding module found by sugar cane soil metagenome, complexed with cellopentaose 分子名称: Carbohydrate binding module E1, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Liberato, M.V, Campos, B.M, Zeri, A.C.M, Squina, F.M. 登録日 2016-06-24 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties. J.Biol.Chem., 291, 2016
7VH4	Crystal structure of oligoribonuclease of Escherichia coli 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Badhwar, P, Taneja, B. 登録日 2021-09-20 公開日 2022-09-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Three-dimensional structure of a mycobacterial oligoribonuclease reveals a unique C-terminal tail that stabilizes the homodimer. J.Biol.Chem., 298, 2022
5EL8	The structure of DHAR1 from Arabidopsis thaliana 分子名称: GLYCEROL, Glutathione S-transferase DHAR1, mitochondrial 著者 Menault, M, Roszak, A.W, Lapthorn, A.J. 登録日 2015-11-04 公開日 2016-11-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Arabidopsis thaliana DHAR1 apo structure To Be Published
8BV7	Crystal structure of the Trichoplax Scribble PDZ1 domain in complex with the Trichoplax phosphorylated Vangl peptide 分子名称: Leucine-rich repeat-containing protein 1, Vang-like protein 1 著者 Maddumage, J.C, Kvansakul, M. 登録日 2022-12-02 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Trichoplax Scribble PDZ1 domain in complex with Trichoplax the phosphorylated Vangl peptide To Be Published
6LLB	Crystal structure of mpy-RNase J (mutant S247A), an archaeal RNase J from Methanolobus psychrophilus R15, in complex with 6 nt RNA 分子名称: MPY-RNase J, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION, ... 著者 Li, D.F, Hou, Y.J, Guo, L. 登録日 2019-12-22 公開日 2020-01-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A newly identified duplex RNA unwinding activity of archaeal RNase J depends on processive exoribonucleolysis coupled steric occlusion by its structural archaeal loops. Rna Biol., 17, 2020
7VEO	Crystal structure of juvenile hormone acid methyltransferase silkworm JHAMT isoform3 complex with S-Adenosyl-L-homocysteine 分子名称: Methyltranfer_dom domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE 著者 Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y. 登録日 2021-09-09 公開日 2022-09-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori. Insect Biochem.Mol.Biol., 151, 2022
7PR3	Cocrystal Form I of a cytochrome c, sulfonato-thiacalix[4]arene - zinc cluster 分子名称: Cytochrome c iso-1, HEME C, PHOSPHATE ION, ... 著者 Flood, R.J, Ramberg, K, Guagnini, F, Crowley, P.B. 登録日 2021-09-20 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Protein Frameworks with Thiacalixarene and Zinc. Cryst.Growth Des., 22, 2022
8K56	Crystal structure of arylamine N-acyltransferase from Streptomyces aureus complexed with acyl-SNAC 分子名称: SULFATE ION, arylamine N-acyltransferase, ~{S}-(2-acetamidoethyl) (~{E})-oct-2-enethioate 著者 Ma, B.D, Yan, X, Qu, X, Kong, X.D. 登録日 2023-07-21 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of arylamine N-acyltransferase from Streptomyces aureus complexed with acyl-SNAC To Be Published
8BRF	YopQ apo from Yersinia enterocolitica 分子名称: CHLORIDE ION, Protein YopQ, SULFATE ION 著者 Sung, S, Blaha, J, Wilmanns, M. 登録日 2022-11-23 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 YopQ apo from Yersinia enterocolitica To Be Published
7Q0M	Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A 分子名称: (2~{S})-2-[[(2~{S})-2-azanyl-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoyl]amino]-3-methyl-butanoic acid, Peptide transporter YePEPT, UNDECYL-MALTOSIDE 著者 Jeckelmann, J.M, Stauffer, M, Ilgue, H, Fotiadis, D. 登録日 2021-10-15 公開日 2022-03-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5, 2022
5VUR	Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-(2-(((2-Aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile 分子名称: 4-(2-{[(2-aminoquinolin-7-yl)methyl]amino}ethyl)-2-methylbenzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2017-05-19 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem., 60, 2017

<581582583584585586587588589590591592593594595596>