3MU6
 
 | | Inhibiting the Binding of Class IIa Histone Deacetylases to Myocyte Enhancer Factor-2 by Small Molecules | | 分子名称: | (3E)-N~8~-(2-aminophenyl)-N~1~-phenyloct-3-enediamide, DNA (5'-D(*AP*AP*AP*GP*CP*TP*AP*TP*TP*AP*TP*TP*AP*GP*CP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*GP*CP*TP*AP*AP*TP*AP*AP*TP*AP*GP*CP*TP*T)-3'), ... | | 著者 | Jayathilaka, N, Han, A, Gaffney, K, Dey, R, He, J, Ye, J, Gao, T, Petasis, N.A, Chen, L. | | 登録日 | 2010-05-01 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.434 Å) | | 主引用文献 | Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2.
Nucleic Acids Res., 40, 2012
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4PII
 | | Crystal structure of hypothetical protein PF0907 from pyrococcus furiosus solved by sulfur SAD using Swiss light source data | | 分子名称: | CHLORIDE ION, IMIDAZOLE, N-glycosylase/DNA lyase | | 著者 | Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2014-05-08 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
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6X5A
 | | The mouse cGAS catalytic domain binding to human nucleosome that purified from HEK293T cells | | 分子名称: | Cyclic GMP-AMP synthase, DNA (natural), Histone H2A type 1, ... | | 著者 | Pengbiao, X, Pingwei, L, Baoyu, Z. | | 登録日 | 2020-05-25 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | | 主引用文献 | The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
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4BE2
 | | PFV intasome with inhibitor XZ-259 | | 分子名称: | 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND) *AP*CP*A)-3', 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 2-(3-chloro-4-fluorobenzyl)-6,7-dihydroxy-N,N-dimethyl-1-oxo-2,3-dihydro-1H-isoindole-4-sulfonamide, ... | | 著者 | Hare, S, Cherepanov, P. | | 登録日 | 2012-10-08 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Activities, Crystal Structures and Molecular Dynamics of Dihydro-1H-Isoindole Derivatives, Inhibitors of HIV-1 Integrase.
Acs Chem.Biol., 8, 2013
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6TYD
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8JNR
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2HYE
 | | Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex | | 分子名称: | Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ... | | 著者 | Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N. | | 登録日 | 2006-08-05 | | 公開日 | 2006-10-03 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
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6FVO
 | | Mutant DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide | | 分子名称: | Beta sliding clamp, CALCIUM ION, P7 peptide | | 著者 | Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. | | 登録日 | 2018-03-04 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.689 Å) | | 主引用文献 | Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
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2QUQ
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8T3W
 | | Structure of Bre1-nucleosome complex - state2 | | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
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8T3Y
 | | Structure of Bre1-nucleosome complex - state1 | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-08 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
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8T3T
 | | Structure of Bre1-nucleosome complex - state3 | | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
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7YYH
 | | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | 登録日 | 2022-02-17 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
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5TN0
 | | Solution Structure of the N-terminal DNA-binding domain of the master biofilm-regulator SinR from Bacillus subtilis | | 分子名称: | HTH-type transcriptional regulator SinR | | 著者 | Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J. | | 登録日 | 2016-10-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
J.Mol.Biol., 2019
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2MB3
 | | Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative | | 分子名称: | (12S,27S)-12,27-bis(4-aminobutyl)-4,30-dimethyl-3,7,14,18,22,29-hexaoxa-11,26,31,32,33,34,35,36-octaazaheptacyclo[26.2. 1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]hexatriaconta-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-dode caene-10,25-dione, DNA_(5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3') | | 著者 | Chung, W.J, Heddi, B, Tera, M, Iida, K, Nagasawa, K, Phan, A.T. | | 登録日 | 2013-07-24 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of an intramolecular (3 + 1) human telomeric g-quadruplex bound to a telomestatin derivative.
J.Am.Chem.Soc., 135, 2013
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3MGQ
 | | Binding of Nickel ions to the Nucleosome Core Particle | | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | | 著者 | Mohideen, K, Muhammad, R, Davey, C.A. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
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3MGS
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7BZG
 | | Structure of Bacillus subtilis HxlR, wild type in complex with formaldehyde and DNA | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*GP*TP*AP*TP*CP*CP*TP*CP*GP*AP*GP*GP*AP*TP*AP*CP*TP*G)-3'), ... | | 著者 | Zhu, R, Chen, P.R. | | 登録日 | 2020-04-27 | | 公開日 | 2021-02-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction.
Nat Commun, 12, 2021
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6PQN
 | | Crystal structure of HzTransib transposase | | 分子名称: | GLYCEROL, PHOSPHATE ION, Putative DNA-mediated transposase, ... | | 著者 | Liu, C, Yang, Y, Schatz, D.G. | | 登録日 | 2019-07-09 | | 公開日 | 2019-10-09 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
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2BJ3
 | | NIKR-apo | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NICKEL RESPONSIVE REGULATOR | | 著者 | Tahirov, T.H. | | 登録日 | 2005-01-28 | | 公開日 | 2005-04-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition
J.Mol.Biol., 348, 2005
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3MGR
 | | Binding of Rubidium ions to the Nucleosome Core Particle | | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | | 著者 | Mohideen, K, Muhammad, R, Davey, C.A. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
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7Q0N
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3MGP
 | | Binding of Cobalt ions to the Nucleosome Core Particle | | 分子名称: | CHLORIDE ION, COBALT (II) ION, DNA (147-MER), ... | | 著者 | Mohideen, K, Muhammad, R, Davey, C.A. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
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3CO3
 | | X-Ray Crystal Structure of a Monofunctional Platinum-DNA Adduct, cis-{Pt(NH3)2(pyridine)}2+ Bound to Deoxyguanosine in a Dodecamer Duplex | | 分子名称: | 5'-D(*DCP*DCP*DTP*DCP*DTP*DCP*DGP*DTP*DCP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DGP*DAP*DGP*DAP*DGP*DG)-3', cis-diammine(pyridine)chloroplatinum(II) | | 著者 | Lovejoy, K.S, Todd, R.C, Zhang, S, McCormick, M.S, D'Aquino, J.A, Reardon, J.T, Sancar, A, Giacomini, K.M, Lippard, S.J. | | 登録日 | 2008-03-27 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2GIJ
 | | Q138F HincII bound to cognate DNA GTTAAC and Ca2+ | | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*TP*AP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, SODIUM ION, ... | | 著者 | Horton, N.C, Joshi, H.K. | | 登録日 | 2006-03-28 | | 公開日 | 2006-07-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
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