PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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4YD1	Ternary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate and an incoming nonhydrolyzable dUMPNPP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Moon, A.F, Gosavi, R.A, Kunkel, T.A, Pedersen, L.C, Bebenek, K. 登録日 2015-02-20 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Creative template-dependent synthesis by human polymerase mu. Proc.Natl.Acad.Sci.USA, 112, 2015
7ZGP	Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA 分子名称: MPE1 isoform 1, Polyadenylation factor subunit 2, Protein CFT1, ... 著者 Rodriguez-Molina, J.B, Passmore, L.A. 登録日 2022-04-04 公開日 2022-05-25 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Mol.Cell, 82, 2022
7ZGR	Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA 分子名称: Cleavage factor two protein 2, MPE1 isoform 1, Polyadenylation factor subunit 2, ... 著者 Rodriguez-Molina, J.B, Passmore, L.A. 登録日 2022-04-04 公開日 2022-05-25 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Mol.Cell, 82, 2022
6QI9	Truncated human R2TP complex, structure 4 (ADP-empty) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-05-15 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.63 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6QI8	Truncated human R2TP complex, structure 3 (ADP-filled) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-04-10 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
7ZGQ	Polymerase module of yeast CPF in complex with the yPIM of Cft2 分子名称: Cleavage factor two protein 2, Polyadenylation factor subunit 2, Protein CFT1, ... 著者 Rodriguez-Molina, J.B, Passmore, L.A. 登録日 2022-04-04 公開日 2022-05-25 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Mol.Cell, 82, 2022
7YES	The structure of EBOV L-VP35-RNA complex (state2) 分子名称: RNA-directed RNA polymerase L, VP35 of EBOV L-VP35 complex, ZINC ION 著者 Shi, Y, Yuan, B, Peng, Q. 登録日 2022-07-06 公開日 2022-10-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of the Ebola virus polymerase complex. Nature, 610, 2022
6EVJ	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primer 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(GDM))-R(P*AP*AP*U)-3'), ... 著者 Pflug, A, Cusack, S. 登録日 2017-11-01 公開日 2017-12-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
8FMA	Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer 分子名称: RNA-directed RNA polymerase 著者 Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. 登録日 2022-12-22 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. Proc.Natl.Acad.Sci.USA, 120, 2023
8FM9	Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer 分子名称: RNA-directed RNA polymerase 著者 Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. 登録日 2022-12-22 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. Proc.Natl.Acad.Sci.USA, 120, 2023
8FMB	Nodavirus RNA replication protein A polymerase domain, local refinement 分子名称: RNA-directed RNA polymerase 著者 Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. 登録日 2022-12-22 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. Proc.Natl.Acad.Sci.USA, 120, 2023
6K32	RdRp complex 分子名称: 2'-O-methyladenosine 5'-(dihydrogen phosphate), 7-METHYLGUANOSINE, DIPHOSPHATE, ... 著者 Li, X.W. 登録日 2019-05-16 公開日 2019-11-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of RdRps Within a Transcribing dsRNA Virus Provides Insights Into the Mechanisms of RNA Synthesis. J.Mol.Biol., 432, 2020
3OTC	Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II 分子名称: tRNA(His) guanylyltransferase 著者 Hyde, S.J, Eckenroth, B.E, Doublie, S. 登録日 2010-09-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
3OTE	Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I 分子名称: tRNA(His) guanylyltransferase 著者 Hyde, S.J, Eckenroth, B.E, Doublie, S. 登録日 2010-09-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
7COC	Ternary complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA (T:dGMPNPP) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7COB	Ternary complex of DNA polymerase Mu (Q441A) with 1-nt gapped DNA (T:dGMPNPP) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7CO8	Ternary complex of DNA polymerase Mu with 2-nt gapped DNA (T:dGMPNPP) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.697 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7CO9	Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mg 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
7COA	Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mn 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... 著者 Guo, M, Zhao, Y. 登録日 2020-08-04 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
8C4S	Apo Hantaan virus polymerase core 分子名称: RNA-directed RNA polymerase L 著者 Durieux trouilleton, Q, Arragain, B, Malet, H. 登録日 2023-01-04 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication. Nat Commun, 14, 2023
8C2P	FMDV 3D polymerase in complex with 3B3 分子名称: Protein 3B-3, RNA-directed RNA polymerase 3D-POL 著者 Ferrer-Orta, C, Veraguer, N. 登録日 2022-12-22 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
2VY8	The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627 分子名称: POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. 登録日 2008-07-19 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
8C1N	FMDV 3D polymerase in complex with 3B1 protein solved in P212121 space group 分子名称: ACETATE ION, GLYCEROL, Protein 3B-1, ... 著者 Ferrer-Orta, C, Veraguer, N. 登録日 2022-12-20 公開日 2023-04-26 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
6YYT	Structure of replicating SARS-CoV-2 polymerase 分子名称: RNA product, ZINC ION, nsp12, ... 著者 Hillen, H.S, Kokic, G, Farnung, L, Dienemann, C, Tegunov, D, Cramer, P. 登録日 2020-05-06 公開日 2020-05-13 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of replicating SARS-CoV-2 polymerase. Nature, 584, 2020
4AU6	Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles 分子名称: RNA-DEPENDENT RNA POLYMERASE 著者 Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C. 登録日 2012-05-14 公開日 2012-06-13 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Location of the Dsrna-Dependent Polymerase, Vp1, in Rotavirus Particles. J.Mol.Biol., 425, 2013

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