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5B1I
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Crystal structure of K42A mutant of cystathionine beta-synthase from Lactobacillus plantarum in a complex with L-methionine
分子名称: Cystathionine beta-synthase, N-[(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXYPHOSPHORANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLENE]METHIONINE, SULFATE ION
著者Matoba, Y, Sugiyama, M.
登録日2015-12-04
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystallographic and mutational analyses of cystathionine beta-synthase in the H2 S-synthetic gene cluster in Lactobacillus plantarum
Protein Sci., 26, 2017
5E0B
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BU of 5e0b by Molmil
Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution
分子名称: GLYCEROL, L(+)-TARTARIC ACID, N-acetyl-beta-muramic acid, ...
著者Sharma, P, Yamini, S, Dube, D, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2015-09-28
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution
To Be Published
5H5J
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BU of 5h5j by Molmil
Complex between ferredoxin and ferredoxin-NADP+ reductase from maize root
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, ...
著者Kurisu, G, Hase, T.
登録日2016-11-05
公開日2017-02-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the isotype-specific interactions of ferredoxin and ferredoxin: NADP(+) oxidoreductase: an evolutionary switch between photosynthetic and heterotrophic assimilation
Photosyn. Res., 134, 2017
5E96
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BU of 5e96 by Molmil
Crystal structure of aminoglycoside 6'-acetyltransferase type Ii
分子名称: 1,2-ETHANEDIOL, Aminoglycoside 6'-acetyltransferase, PHOSPHATE ION
著者Berghuis, A.M, Burk, D.L, Baettig, O.M, Shi, K.
登録日2015-10-14
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Comprehensive characterization of ligand-induced plasticity changes in a dimeric enzyme.
Febs J., 283, 2016
4I23
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BU of 4i23 by Molmil
Crystal structure of the wild-type EGFR kinase domain in complex with dacomitinib (soaked)
分子名称: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide, Epidermal growth factor receptor
著者Gajiwala, K.S, Feng, J, Ferre, R, Ryan, K, Brodsky, O, Stewart, A.
登録日2012-11-21
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition.
Structure, 21, 2013
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-14
公開日2023-05-03
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
4PXA
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BU of 4pxa by Molmil
DEAD-box RNA helicase DDX3X Cancer-associated mutant D354V
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX3X, PHOSPHATE ION
著者Epling, L.B, Grace, C.R, Lowe, B.R, Partridge, J.F, Enemark, E.J.
登録日2014-03-22
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis.
J.Mol.Biol., 427, 2015
8CSJ
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BU of 8csj by Molmil
Cryo-EM structure of NTD-directed non-neutralizing antibody 4-33 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(2-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Reddem, E.R, Shapiro, L.
登録日2022-05-12
公開日2023-05-17
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Cryo-EM structure of NTD-directed non-neutralizing antibody 4-33 in complex with prefusion SARS-CoV-2 spike glycoprotein
To Be Published
5KW6
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BU of 5kw6 by Molmil
Two Tandem RRM Domains of PUF60 Bound to an AdML Pre-mRNA 3' Splice Site Analogue with a Modified Binding-Site Nucleic Acid Base
分子名称: DNA (30-MER), Poly(U)-binding-splicing factor PUF60
著者Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
登録日2016-07-15
公開日2017-08-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-24
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-24
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CDA
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BU of 8cda by Molmil
Crystal structure of MAB_4123 from Mycobacterium abscessus
分子名称: GLYCEROL, PHOSPHATE ION, Probable monooxygenase
著者Ung, K.L, Poussineau, C, Couston, J, Alsarraf, H.M.A.B, Blaise, M.
登録日2023-01-30
公開日2023-05-10
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of MAB_4123, a putative flavin-dependent monooxygenase from Mycobacterium abscessus.
Acta Crystallogr.,Sect.F, 79, 2023
8CBJ
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BU of 8cbj by Molmil
Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex
分子名称: 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-25
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Cretu, C, Schmitzova, J, Pena, V.
登録日2023-02-07
公開日2023-05-10
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
6IDG
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BU of 6idg by Molmil
antibody 64M-5 Fab in complex with dT(6-4)T
分子名称: Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), DNA (5'-D(*(64T)P*(5PY))-3')
著者Yokoyama, H, Mizutani, R, Noguchi, S, Hayashida, N.
登録日2018-09-10
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the antibody 64M-5 Fab and its complex with dT(6-4)T indicate induced-fit and high-affinity mechanisms.
Acta Crystallogr.,Sect.F, 75, 2019
8CIM
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BU of 8cim by Molmil
BA.2-07 FAB IN COMPLEX WITH SARS-COV-2 BA.2.12.1 SPIKE GLYCOPROTEIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA.2-07 FAB HEAVY CHAIN, ...
著者Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E.
登録日2023-02-10
公開日2023-07-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Isolation of a pair of potent broadly neutralizing mAb binding to RBD and SD1 domains of SARS-CoV-2
Res Sq, 2023
8CCQ
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BU of 8ccq by Molmil
Crystal structure of arsenite oxidase from Pseudorhizobium banfieldiae str. NT-26 (NT-26 Aio) bound to antimony trioxide
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, AroA, ...
著者Engrola, F, Santos-Silva, T, Romao, M.J, Correia, M.A.S.
登録日2023-01-27
公開日2023-07-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Arsenite oxidase in complex with antimonite and arsenite oxyanions: Insights into the catalytic mechanism.
J.Biol.Chem., 299, 2023
8C8T
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BU of 8c8t by Molmil
cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Baquero, E, Molinos-Albert, L, Mouquet, H.
登録日2023-01-21
公開日2023-07-05
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.
Cell Host Microbe, 31, 2023
8CFF
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BU of 8cff by Molmil
Crystal structure of arsenite oxidase from Alcaligenes faecalis (Af Aio) bound to arsenite
分子名称: 1,2-ETHANEDIOL, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, ARSENITE, ...
著者Engrola, F, Correia, M.A.S, Romao, M.J, Santos-Silva, T.
登録日2023-02-03
公開日2023-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Arsenite oxidase in complex with antimonite and arsenite oxyanions: Insights into the catalytic mechanism.
J.Biol.Chem., 299, 2023
8C6J
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BU of 8c6j by Molmil
Human spliceosomal PM5 C* complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Dybkov, O, Kastner, B, Luehrmann, R.
登録日2023-01-12
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
8CEP
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BU of 8cep by Molmil
Kasugamycin bound to the 30S body
分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S rRNA, 23S rRNA, ...
著者Paternoga, H, Beckert, B, Wilson, D.N.
登録日2023-02-02
公開日2023-07-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CAI
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BU of 8cai by Molmil
Streptomycin and Hygromycin B bound to the 30S body
分子名称: 16S rRNA, 30S ribosomal protein S16, 30S ribosomal protein S2, ...
著者Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
登録日2023-01-24
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CAZ
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BU of 8caz by Molmil
empty 30S head
分子名称: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
著者Paternoga, H, Beckert, B, Wilson, D.N.
登録日2023-01-24
公開日2023-07-26
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.11 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGI
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BU of 8cgi by Molmil
Pentacycline TP038 bound to the 30S head
分子名称: 16S rRNA, 30S ribosomal protein S7, Large ribosomal subunit protein bL31A, ...
著者Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
登録日2023-02-04
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (1.89 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGK
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Lincomycin and Avilamycin bound to the 50S subunit
分子名称: (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 23S rRNA, 50S ribosomal protein L15, ...
著者Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
登録日2023-02-05
公開日2023-07-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.64 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023

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