1EMD
 
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4K5K
 | | Structure of bovine endothelial nitric oxide synthase heme domain in complex with ((2S, 3S)-1,3-bis((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methoxy)-2-aminobutane | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6,6'-{[(2S,3S)-2-aminobutane-1,3-diyl]bis(oxymethanediyl)}bis(4-methylpyridin-2-amine), ACETATE ION, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2013-04-14 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
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4K74
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1EQM
 | | CRYSTAL STRUCTURE OF BINARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE WITH ADENOSINE-5'-DIPHOSPHATE | | 分子名称: | 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Xiao, B, Blaszczyk, J, Ji, X. | | 登録日 | 2000-04-05 | | 公開日 | 2001-04-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR.
J.Biol.Chem., 276, 2001
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1ERJ
 | | CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1 | | 分子名称: | TRANSCRIPTIONAL REPRESSOR TUP1 | | 著者 | Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C. | | 登録日 | 2000-04-06 | | 公開日 | 2000-07-26 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
EMBO J., 19, 2000
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4K90
 | | Extracellular metalloproteinase from Aspergillus | | 分子名称: | BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ... | | 著者 | Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I. | | 登録日 | 2013-04-19 | | 公開日 | 2013-10-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.
Acta Crystallogr.,Sect.D, 69, 2013
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1EFM
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5HYT
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1E6I
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1I0U
 | | SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR | | 分子名称: | CALCIUM ION, LOW DENSITY LIPOPROTEIN RECEPTOR | | 著者 | Kurniawan, N.D, Aliabadizadeh, K, Brereton, I.M, Kroon, P.A, Smith, R. | | 登録日 | 2001-01-29 | | 公開日 | 2001-08-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor.
J.Mol.Biol., 311, 2001
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1E7Y
 | | ACTIVE SITE MUTANT (D177->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES COMPLEXED WITH SUBSTRATE AND NADPH | | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, ... | | 著者 | Adams, M.J, Cosgrove, M.S, Gover, S. | | 登録日 | 2000-09-12 | | 公開日 | 2000-12-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | An Examination of the Role of Asp-177 in the His-Asp Catalytic Dyad of Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: X-Ray Structure and Ph Dependence of Kinetic Parameters of the D177N Mutant Enzyme
Biochemistry, 39, 2000
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4KDL
 | | Crystal structure of p97/VCP N in complex with OTU1 UBXL | | 分子名称: | Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1 | | 著者 | Kim, S.J, Kim, E.E. | | 登録日 | 2013-04-25 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
J.Biol.Chem., 289, 2014
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4KA2
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1EAA
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1ED4
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH IPITU (H4B FREE) | | 分子名称: | ACETATE ION, CACODYLIC ACID, GLYCEROL, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L. | | 登録日 | 2000-01-26 | | 公開日 | 2000-10-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
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4KHR
 | | HCV NS5B GT1A C316Y with GSK5852 | | 分子名称: | NS5B RNA-dependent RNA polymerase, SULFATE ION, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic acid | | 著者 | Williams, S.P, Kahler, K.M, Shotwell, J.B. | | 登録日 | 2013-05-01 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase.
J.Med.Chem., 57, 2014
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1EHC
 | | STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN CHEY | | 分子名称: | CHEY, SULFATE ION | | 著者 | Jiang, M, Bourret, R, Simon, M, Volz, K. | | 登録日 | 1996-03-05 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Uncoupled phosphorylation and activation in bacterial chemotaxis. The 2.3 A structure of an aspartate to lysine mutant at position 13 of CheY.
J.Biol.Chem., 272, 1997
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1EDQ
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1EHL
 | | 64M-2 ANTIBODY FAB COMPLEXED WITH D(5HT)(6-4)T | | 分子名称: | 5'-(D(5HT)P*(6-4)T)-3', ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (HEAVY CHAIN), ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (LIGHT CHAIN) | | 著者 | Yokoyama, H, Mizutani, R, Satow, Y, Komatsu, Y, Ohtsuka, E, Nikaido, O. | | 登録日 | 2000-02-21 | | 公開日 | 2001-02-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation.
J.Mol.Biol., 299, 2000
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4KIS
 | | Crystal Structure of a LSR-DNA Complex | | 分子名称: | CALCIUM ION, DNA (26-MER), Putative integrase [Bacteriophage A118], ... | | 著者 | Rutherford, K, Yuan, P, Perry, K, Van Duyne, G.D. | | 登録日 | 2013-05-02 | | 公開日 | 2013-07-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Attachment site recognition and regulation of directionality by the serine integrases.
Nucleic Acids Res., 41, 2013
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4KFD
 | | Crystal structure of Hansenula polymorpha copper amine oxidase-1 reduced by methylamine at pH 6.0 | | 分子名称: | COPPER (II) ION, GLYCEROL, HYDROGEN PEROXIDE, ... | | 著者 | Johnson, B.J, Yukl, E.T, Klema, V.J, Wilmot, C.M. | | 登録日 | 2013-04-26 | | 公開日 | 2013-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural evidence for the semiquinone in a copper amine oxidase from Hansenula polymorpha: implications for the catalytic mechanism
J.Biol.Chem., 2013
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1EG9
 | | NAPHTHALENE 1,2-DIOXYGENASE WITH INDOLE BOUND IN THE ACTIVE SITE. | | 分子名称: | FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, INDOLE, ... | | 著者 | Carredano, E, Karlsson, A, Kauppi, B, Choudhury, D, Parales, R.E, Parales, J.V, Lee, K, Gibson, D.T, Eklund, H, Ramaswamy, S. | | 登録日 | 2000-02-15 | | 公開日 | 2000-05-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Substrate binding site of naphthalene 1,2-dioxygenase: functional implications of indole binding.
J.Mol.Biol., 296, 2000
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1I6V
 | | THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX | | 分子名称: | DNA-DIRECTED RNA POLYMERASE, MAGNESIUM ION, RIFAMPICIN, ... | | 著者 | Campbell, E.A, Korzheva, N, Mustaev, A, Murakami, K, Goldfarb, A, Darst, S.A. | | 登録日 | 2001-03-05 | | 公開日 | 2001-04-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural mechanism for rifampicin inhibition of bacterial rna polymerase.
Cell(Cambridge,Mass.), 104, 2001
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1EGP
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1I5L
 | | CRYSTAL STRUCTURE OF AN SM-LIKE PROTEIN (AF-SM1) FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH SHORT POLY-U RNA | | 分子名称: | 5'-R(*UP*UP*U)-3', PUTATIVE SNRNP SM-LIKE PROTEIN AF-SM1, URIDINE | | 著者 | Toro, I, Thore, S, Mayer, C, Basquin, J, Seraphin, B, Suck, D. | | 登録日 | 2001-02-28 | | 公開日 | 2001-08-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex.
EMBO J., 20, 2001
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