PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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3MSL	Fragment Based Discovery and Optimisation of BACE-1 Inhibitors 分子名称: (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(cyclohexylmethyl)pentanamide, Beta-secretase 1, IODIDE ION 著者 Smith, M, Madden, J, Barker, J. 登録日 2010-04-29 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
3DCL	Crystal structure of TM1086 分子名称: CHLORIDE ION, POTASSIUM ION, SULFATE ION, ... 著者 Chruszcz, M, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2008-06-03 公開日 2008-08-05 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of TM1086 To be Published
3ME2	Crystal structure of mouse RANKL-RANK complex 分子名称: CHLORIDE ION, SODIUM ION, Tumor necrosis factor ligand superfamily member 11, ... 著者 Walter, S.W, Liu, C.Z, Zhu, X.K, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. 登録日 2010-03-31 公開日 2010-06-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Functional Insights of RANKL-RANK Interaction and Signaling. J.Immunol., 2010
3MEC	HIV-1 Reverse Transcriptase in Complex with TMC125 分子名称: 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE, SULFATE ION, p51 Reverse transcriptase, ... 著者 Lansdon, E.B. 登録日 2010-03-31 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design. J.Med.Chem., 53, 2010
4K9O	Crystal Structure of the Phe397Ala mutant of Benzoylformate Decarboxylase from Pseudomonas putida 分子名称: Benzoylformate decarboxylase, CALCIUM ION, GLYCEROL, ... 著者 Brodkin, H.R, McLeish, M.J. 登録日 2013-04-20 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.888 Å) 主引用文献 Crystal Structure of the Phe397Ala mutant of Benzoylformate Decarboxylase from Pseudomonas putida To be Published
3MT6	Structure of ClpP from Escherichia coli in complex with ADEP1 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACYLDEPSIPEPTIDE 1, ATP-dependent Clp protease proteolytic subunit 著者 Chung, Y.S. 登録日 2010-04-30 公開日 2010-11-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. Chem.Biol., 17, 2010
3D9B	Symmetric structure of E. coli AcrB 分子名称: Acriflavine resistance protein B, NICKEL (II) ION 著者 Veesler, D, Blangy, S, Cambillau, C, Sciara, G. 登録日 2008-05-27 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization. Acta Crystallogr.,Sect.F, 64, 2008
4UJ5	Crystal structure of human Rab11-Rabin8-FIP3 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ... 著者 Vetter, M, Lorentzen, E. 登録日 2015-04-08 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.604 Å) 主引用文献 Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11. Nat.Struct.Mol.Biol., 22, 2015
3MF5	Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor 分子名称: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase 著者 Harris, S.F, Tavares, G, Ghate, M. 登録日 2010-04-01 公開日 2010-07-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
4KAT	Crystal structure of FDTS from T. maritima mutant (R174K) with FAD and dUMP 分子名称: 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Thymidylate synthase 著者 Mathews, I.I. 登録日 2013-04-22 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef, Suppl 12, 2013
3D95	Crystal Structure of the R132K:Y134F:R111L:L121E:T54V Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.20 Angstroms Resolution 分子名称: Cellular retinoic acid-binding protein 2 著者 Vaezeslami, S, Geiger, J.H. 登録日 2008-05-26 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural analysis of site-directed mutants of cellular retinoic acid-binding protein II addresses the relationship between structural integrity and ligand binding. Acta Crystallogr.,Sect.D, 64, 2008
3MFU	CASK-4M CaM Kinase Domain, AMPPNP-Mn2+ 分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Peripheral plasma membrane protein CASK 著者 Wahl, M.C, Mukherjee, K. 登録日 2010-04-03 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evolution of CASK into a Mg2+-sensitive kinase. Sci.Signal., 3, 2010
3LZZ	Crystal structures of Cupin superfamily BbDUF985 from Branchiostoma belcheri tsingtauense in apo and GDP-bound forms 分子名称: ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, Putative uncharacterized protein 著者 Du, Y, He, Y.-X, Saren, G, Zhang, X, Zhang, S.-C, Chen, Y, Zhou, C.-Z. 登録日 2010-03-02 公開日 2010-06-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of the apo and GDP-bound forms of a cupin-like protein BbDUF985 from Branchiostoma belcheri tsingtauense Proteins, 2010
4KNF	Crystal structure of a blue-light absorbing proteorhodopsin double-mutant D97N/Q105L from HOT75 分子名称: Blue-light absorbing proteorhodopsin, RETINAL 著者 Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H. 登録日 2013-05-09 公開日 2013-06-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes. Acta Crystallogr.,Sect.D, 69, 2013
3D9I	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II 分子名称: AMMONIUM ION, GLYCEROL, RNA-binding protein 16, ... 著者 Becker, R, Loll, B, Meinhart, A. 登録日 2008-05-27 公開日 2008-06-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.907 Å) 主引用文献 Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
4WA4	The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with oseltamivir carboxylate 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase, ... 著者 Yang, H, Villanueva, J.M, Gubareva, L.V, Stevens, J. 登録日 2014-08-28 公開日 2015-01-14 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals. J.Virol., 89, 2015
4KBC	CK1d in complex with {4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDIN-2-YL}METHANOL inhibitor 分子名称: 1,2-ETHANEDIOL, Casein kinase I isoform delta, SULFATE ION, ... 著者 Liu, S. 登録日 2013-04-23 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Ligand-protein interactions of selective casein kinase 1 delta inhibitors. J.Med.Chem., 56, 2013
3DA3	Crystal Structure of Colicin M, A Novel Phosphatase Specifically Imported by Escherichia Coli 分子名称: Colicin-M, MAGNESIUM ION 著者 Zeth, K, Albrecht, R, Romer, C, Braun, V. 登録日 2008-05-28 公開日 2008-09-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of colicin M, a novel phosphatase specifically imported by Escherichia coli J.Biol.Chem., 283, 2008
3M0B	Ru-Porphyrin Protein Scaffolds for Sensing O2 分子名称: CARBON MONOXIDE, Methyl-accepting chemotaxis protein, [3,3'-(7,12-diethyl-3,8,13,17-tetramethylporphyrin-2,18-diyl-kappa~4~N~21~,N~22~,N~23~,N~24~)dipropanoato(2-)]ruthenium 著者 Winter, M.B, McLaurin, E.J, Reece, S.Y, Olea Jr, C, Nocera, D.G, Marletta, M.A. 登録日 2010-03-02 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ru-porphyrin protein scaffolds for sensing O2. J.Am.Chem.Soc., 132, 2010
3M0J	Structure of oxaloacetate acetylhydrolase in complex with the inhibitor 3,3-difluorooxalacetate 分子名称: 2,2-difluoro-3,3-dihydroxybutanedioic acid, CALCIUM ION, MANGANESE (II) ION, ... 著者 Herzberg, O, Chen, C. 登録日 2010-03-03 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. J.Biol.Chem., 285, 2010
4KNT	Copper nitrite reductase from Nitrosomonas europaea pH 8.5 分子名称: COPPER (II) ION, GLYCEROL, Multicopper oxidase type 1 著者 Rosenzweig, A.C, Lawton, T.L, Sayavedra-Soto, L.A, Arp, D.J. 登録日 2013-05-10 公開日 2013-07-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of a nitrite reductase involved in nitrifier denitrification. J.Biol.Chem., 288, 2013
4UJA	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-{(3S,4R)-4-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}quinazolin-4(3H)-one, BROMIDE ION, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-09 公開日 2016-04-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
3DAW	Structure of the actin-depolymerizing factor homology domain in complex with actin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Paavilainen, V.O, Oksanen, E, Goldman, A, Lappalainen, P. 登録日 2008-05-30 公開日 2008-07-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of the actin-depolymerizing factor homology domain in complex with actin J.Cell Biol., 182, 2008
3D8B	Crystal structure of human fidgetin-like protein 1 in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Fidgetin-like protein 1 著者 Karlberg, T, Wisniewska, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Welin, M, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2008-05-23 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Human fidgetin-like protein 1. To be Published
3M1O	Human Transthyretin (TTR) complexed with 2-((3,5-dichloro-4-hydroxyphenyl)amino)benzoic acid 分子名称: 2-[(3,5-dichloro-4-hydroxyphenyl)amino]benzoic acid, Transthyretin 著者 Kolstoe, S.E, Wood, S.P. 登録日 2010-03-05 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc.Natl.Acad.Sci.USA, 107, 2010

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