PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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5K79	Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog 分子名称: 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER 著者 Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M. 登録日 2016-05-25 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and Glycan Binding of a New Cyanovirin-N Homolog. J.Biol.Chem., 291, 2016
4M14	Crystal structure of ITK in complex with compound 9 [4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide] 分子名称: 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK 著者 Han, S, Caspers, N.L. 登録日 2013-08-02 公開日 2014-04-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors. Biochem.J., 460, 2014
4M15	Crystal structure of ITK in complex with compound 9 [4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide] and ADP 分子名称: 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1H-pyrazole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Tyrosine-protein kinase ITK/TSK 著者 Han, S, Caspers, N.L. 登録日 2013-08-02 公開日 2014-04-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors. Biochem.J., 460, 2014
4M0Y	Crystal structure of ITK in complex with compound 1 [4-(carbamoylamino)-1-(naphthalen-1-yl)-1H-pyrazole-3-carboxamide] 分子名称: 4-(carbamoylamino)-1-(naphthalen-1-yl)-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK 著者 Han, S, Caspers, N.L. 登録日 2013-08-02 公開日 2014-04-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors. Biochem.J., 460, 2014
4MGP	Structure of racemic Ala-(8,13,18) Magainin 2 分子名称: Magainin 2 Derivative 著者 Hayouka, Z, Mortenson, D.E, Kreitler, D.F, Weisblum, B, Gellman, S.H, Forest, K.T. 登録日 2013-08-28 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 Analogue. J.Am.Chem.Soc., 135, 2013
4LPZ	ARNT transcription factor/coactivator complex 分子名称: Aryl hydrocarbon receptor nuclear translocator, Transforming acidic coiled-coil-containing protein 3 著者 Guo, Y, Scheuermann, T.H, Gardner, K.H. 登録日 2013-07-16 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization. J.Biol.Chem., 290, 2015
4NL5	Mycobacterium tuberculosis heme-degrading protein MhuD in complex with heme and cyanide 分子名称: ACETATE ION, CYANIDE ION, Heme-degrading monooxygenase HmoB, ... 著者 Morse, R.P, Chao, A, Goulding, C.W. 登録日 2013-11-13 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic and Spectroscopic Insights into Heme Degradation by Mycobacterium tuberculosis MhuD. Inorg.Chem., 53, 2014
4NLF	2'-trifluoromethylthio-2'-deoxycytidine-modified SRL 分子名称: 23S ribosomal RNA Sarcin Ricin Loop, SULFATE ION 著者 Ennifar, E, Micura, R, Kosutic, M. 登録日 2013-11-14 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids. J.Am.Chem.Soc., 136, 2014
4N5X	Crystal structure of N-terminal calmodulin-like Calcium sensor of human mitochondrial ATP-Mg/Pi carrier SCaMC1 分子名称: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, DI(HYDROXYETHYL)ETHER 著者 Yang, Q, Bruschweiler, S, Chou, J. 登録日 2013-10-10 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Self-Sequestered Calmodulin-like Ca(2+) Sensor of Mitochondrial SCaMC Carrier and Its Implication to Ca(2+)-Dependent ATP-Mg/Pi Transport. Structure, 22, 2014
7K6S	Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to Compound 4 (SKT1174) 分子名称: (7-amino-3,4-dihydroquinolin-1(2H)-yl)(cyclopropyl)methanone, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Chan, A, Schonbrunn, E. 登録日 2020-09-21 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development. Org.Biomol.Chem., 18, 2020
7KDW	Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to Compound 6 (HZ01052) 分子名称: 1,2-ETHANEDIOL, Nucleosome-remodeling factor subunit BPTF, cyclopropyl[7-({2-[(prop-2-yn-1-yl)amino]pyrimidin-4-yl}amino)-3,4-dihydroquinolin-1(2H)-yl]methanone 著者 Chan, A, Schonbrunn, E. 登録日 2020-10-09 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development Organic and Biomolecular Chemistry, 18(27), 2020
4NAM	1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G. 登録日 2013-10-22 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 (19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability. Biochemistry, 53, 2014
7K6R	Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to GSK4027 分子名称: 1,2-ETHANEDIOL, 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one, Nucleosome-remodeling factor subunit BPTF 著者 Chan, A, Schonbrunn, E. 登録日 2020-09-21 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development. Org.Biomol.Chem., 18, 2020
4NXH	2'-Trifluoromethylthiouridine-modified E. coli 23S rRNA Sarcin Ricin Loop 分子名称: 23S ribosomal RNA Sarcin Ricin Loop, GLYCEROL, SULFATE ION 著者 Ennifar, E, Micura, R, Kosutic, M. 登録日 2013-12-09 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.158 Å) 主引用文献 Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids. J.Am.Chem.Soc., 136, 2014
4OYL	Humicola insolens cutinase in complex with mono-ethylphosphate 分子名称: Cutinase 著者 Dauter, Z.D, Brzozowski, A.M, Turkenburg, J.P, Wilson, K.S. 登録日 2014-02-12 公開日 2014-06-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Thermodynamic and structural investigation of the specific SDS binding of Humicola insolens cutinase. Protein Sci., 23, 2014
4OR1	Structure and mechanism of fibronectin binding and biofilm formation of enteroaggregative Escherischia coli AAF fimbriae 分子名称: ACETATE ION, Invasin homolog AafB, Major fimbrial subunit of aggregative adherence fimbria II AafA chimeric construct, ... 著者 Lee, W.-C, Garnett, J.A, Yang, Y, Matthews, S. 登録日 2014-02-10 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli. Plos Pathog., 10, 2014
4OYY	Humicola insolens cutinase 分子名称: Cutinase 著者 Dauter, Z.D, Brzozowski, A.M, Turkenburg, J.P, Wilson, K.S. 登録日 2014-02-13 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase. Protein Sci., 23, 2014
4MHG	Crystal structure of ETV6 bound to a specific DNA sequence 分子名称: Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6 著者 Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P. 登録日 2013-08-29 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6. J.Mol.Biol., 426, 2014
4NMG	2'-Trifluoromethylthio-2'-deoxyuridine-modified SRL 分子名称: 23S ribosomal RNA Sarcin Ricin Loop 著者 Ennifar, E, Micura, R, Kosutic, M. 登録日 2013-11-15 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.01 Å) 主引用文献 Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids. J.Am.Chem.Soc., 136, 2014
4PHX	Crystal structure of AggB, the minor subunit of aggregative adherence fimbriae type I from the Escherichia coli O4H104 分子名称: Protein AggB 著者 Pakharukova, N.A, Tuitilla, M, Zavialov, A.V. 登録日 2014-05-07 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli. Plos Pathog., 10, 2014
3L1Z	Crystal structure of the U-BOX domain of human E4B ubiquitin ligase in complex with UBCH5C E2 ubiquitin conjugating enzyme 分子名称: Ubiquitin conjugation factor E4 B, Ubiquitin-conjugating enzyme E2 D3 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
3L1Y	Crystal structure of human UBC4 E2 conjugating enzyme 分子名称: Ubiquitin-conjugating enzyme E2 D2 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
3LE8	Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.70 Angstrom resolution in complex with 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid 分子名称: 1,2-ETHANEDIOL, 2-(2-((benzofuran-2-carboxamido)methyl)-5-methoxy-1H-indol-1-yl)acetic acid, ETHANOL, ... 著者 Silvestre, H.L, Hung, A.W, Sledz, P, Ciulli, A, Blundell, T.L, Abell, C. 登録日 2010-01-14 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Optimization of the interligand overhauser effect for fragment linking: application to inhibitor discovery against Mycobacterium tuberculosis pantothenate synthetase. J.Am.Chem.Soc., 132, 2010
3L1X	Crystal Structure of U-box Domain of Human E4B Ubiquitin Ligase 分子名称: Ubiquitin conjugation factor E4 B 著者 Benirschke, R, Thompson, J.R, Mer, G. 登録日 2009-12-14 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4. Structure, 18, 2010
3L9Q	Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain 分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION 著者 Vaithiyalingam, S, Eichman, B.F, Chazin, W.J. 登録日 2010-01-05 公開日 2010-07-14 最終更新日 2011-11-16 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc.Natl.Acad.Sci.USA, 107, 2010

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