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6GPK
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BU of 6gpk by Molmil
Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-Man
分子名称: 1,2-ETHANEDIOL, GDP-mannose 4,6 dehydratase, GLYCEROL, ...
著者Pfeiffer, M, Krojer, T, Johansson, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2018-06-06
公開日2018-07-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.
Acs Catalysis, 9, 2019
8IL4
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BU of 8il4 by Molmil
Crystal structure of alcohol oxidase ParAOX(M59V/Q60P/R61N/F101S/N602H)(Polyporus arcularius)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GMC oxidoreductase
著者Wu, B, Wang, Y.
登録日2023-03-01
公開日2024-03-06
実験手法X-RAY DIFFRACTION (3.35500073 Å)
主引用文献Crystal structure of alcohol oxidase ParAOX(M59V/Q60P/R61N/F101S/N602H)(Polyporus arcularius)
To Be Published
5TKF
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BU of 5tkf by Molmil
Neurospora crassa polysaccharide monooxygenase 2 high mannosylation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
著者O'Dell, W.B, Meilleur, F.
登録日2016-10-06
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2V1U
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BU of 2v1u by Molmil
STRUCTURE OF THE AEROPYRUM PERNIX ORC1 PROTEIN IN COMPLEX WITH DNA
分子名称: 5'-D(*AP*CP*CP*CP*CP*TP*CP*CP*GP*TP *TP*TP*CP*CP*TP*GP*TP*GP*GP*AP*GP*A)-3', 5'-D(*TP*CP*TP*CP*CP*AP*CP*AP*GP*GP *AP*AP*AP*CP*GP*GP*AP*GP*GP*GP*GP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Gaudier, M, Schuwirth, B.S, Westcott, S.L, Wigley, D.B.
登録日2007-05-30
公開日2007-09-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis of DNA Replication Origin Recognition by an Orc Protein.
Science, 317, 2007
5L02
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BU of 5l02 by Molmil
S324T variant of B. pseudomallei KatG
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Catalase-peroxidase, PHOSPHATE ION, ...
著者Loewen, P.C.
登録日2016-07-26
公開日2016-08-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei
J. Mol. Biol., 345, 2005
8FET
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BU of 8fet by Molmil
Flavanone 4-Reductase from Sorghum bicolor-NADP(H) complex
分子名称: 3-deoxyanthocyanidin synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, B, Kang, C.
登録日2022-12-06
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Structural Similarities and Overlapping Activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and Anthocyanidin Reductase Offer Metabolic Flexibility in the Flavonoid Pathway.
Int J Mol Sci, 24, 2023
8FEV
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BU of 8fev by Molmil
Flavanone 4-Reductase from Sorghum bicolor-NADP(H) and dihydroquercetin complex
分子名称: (2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, 3-deoxyanthocyanidin synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Zhang, B, Kang, C.
登録日2022-12-06
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural Similarities and Overlapping Activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and Anthocyanidin Reductase Offer Metabolic Flexibility in the Flavonoid Pathway.
Int J Mol Sci, 24, 2023
8FIO
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BU of 8fio by Molmil
Hypothetical anthocyanidin reductase from Sorghum bicolor-NADP(H) and naringenin complex
分子名称: Epimerase domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NARINGENIN
著者Zhang, B, Kang, C.
登録日2022-12-16
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Similarities and Overlapping Activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and Anthocyanidin Reductase Offer Metabolic Flexibility in the Flavonoid Pathway.
Int J Mol Sci, 24, 2023
8FEW
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BU of 8few by Molmil
Flavanone 4-Reductase from Sorghum bicolor-naringenin complex
分子名称: 3-deoxyanthocyanidin synthase, NARINGENIN, SULFATE ION
著者Zhang, B, Kang, C.
登録日2022-12-06
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural Similarities and Overlapping Activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and Anthocyanidin Reductase Offer Metabolic Flexibility in the Flavonoid Pathway.
Int J Mol Sci, 24, 2023
8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
分子名称: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
著者Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
登録日2023-01-06
公開日2023-09-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
8FIP
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BU of 8fip by Molmil
Hypothetical anthocyanidin reducatase from Sorghum bicolor- NADP+ complex
分子名称: Epimerase domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, B, Kang, C.
登録日2022-12-16
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Similarities and Overlapping Activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and Anthocyanidin Reductase Offer Metabolic Flexibility in the Flavonoid Pathway.
Int J Mol Sci, 24, 2023
8FEU
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BU of 8feu by Molmil
Flavanone 4-Reductase from Sorghum bicolor-NADP(H) and naringenin complex
分子名称: 3-deoxyanthocyanidin synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NARINGENIN, ...
著者Zhang, B, Kang, C.
登録日2022-12-06
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural Similarities and Overlapping Activities among Dihydroflavonol 4-Reductase, Flavanone 4-Reductase, and Anthocyanidin Reductase Offer Metabolic Flexibility in the Flavonoid Pathway.
Int J Mol Sci, 24, 2023
8INZ
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BU of 8inz by Molmil
Cryo-EM structure of human HCN3 channel in apo state
分子名称: 4-[[(2~{S},4~{a}~{R},6~{S},8~{a}~{S})-6-[(4~{S},5~{R})-4-[(2~{S})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
著者Yu, B, Lu, Q.Y, Li, J, Zhang, J.
登録日2023-03-10
公開日2024-04-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Cryo-EM structure of human HCN3 channel and its regulation by cAMP.
J.Biol.Chem., 300, 2024
6EUY
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BU of 6euy by Molmil
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
分子名称: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2, SULFATE ION
著者Cusack, S, Gaudon, S.
登録日2017-10-31
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
8DKL
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BU of 8dkl by Molmil
Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates
分子名称: 3C-like proteinase nsp5
著者Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J.
登録日2022-07-05
公開日2023-05-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Acs Cent.Sci., 9, 2023
8CWJ
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BU of 8cwj by Molmil
Fab arms of antibodies 4C12-B12 and CR3022 bound to pangolin receptor binding domain (pRBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Langley, D.B, Christ, D.
登録日2022-05-19
公開日2023-05-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.449 Å)
主引用文献Neutralization of CoV-2 omicron lineages by affinity-matured class 5 antibodies
To Be Published
6SQC
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BU of 6sqc by Molmil
Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076
分子名称: 1,2-ETHANEDIOL, Maltose/maltodextrin-binding periplasmic protein,CREB-binding protein, Nuclear receptor coactivator 3, ...
著者Bauer, V, Schmidtgall, B, Gogl, G, Dolenc, j, Osz, J, Kostmann, C, Mitschler, A, Cousido-Siah, A, Rochel, N, Trave, G, Kieffer, B, Torbeev, V.
登録日2019-09-03
公開日2020-09-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Conformational editing of intrinsically disordered protein by alpha-methylation.
Chem Sci, 12, 2020
5L9K
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BU of 5l9k by Molmil
OCEANOBACILLUS IHEYENSIS MACRODOMAIN WITH ADPR
分子名称: GLYCEROL, MACROD-TYPE MACRODOMAIN, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
著者Gil-Ortiz, F, Zapata-Perez, R, Martinez, A.B, Juanhuix, J, Sanchez-Ferrer, A.
登録日2016-06-10
公開日2017-05-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis.
Open Biol, 7, 2017
4XJ8
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BU of 4xj8 by Molmil
Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 5.0 in 50mM sodium Acetate with DMSO
分子名称: Sialidase B
著者Brear, P.
登録日2015-01-08
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.749 Å)
主引用文献`The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB
To be published
6VER
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BU of 6ver by Molmil
Human insulin analog: [GluB10,TyrB20]-DOI
分子名称: Insulin A chain, Insulin B chain
著者Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X.
登録日2020-01-02
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.047 Å)
主引用文献Mini-Ins: A minimal, bioactive insulin analog with alternative binding modes
not published
4XD1
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BU of 4xd1 by Molmil
X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens, W305A mutant, in the presence of TDP-Qui3N and N5-THF
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ...
著者Thoden, J.B, Woodford, C.R, Holden, H.M.
登録日2014-12-18
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens.
Biochemistry, 54, 2015
7TC7
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BU of 7tc7 by Molmil
Cryo-EM structure of methane monooxygenase hydroxylase (by quantifoil)
分子名称: FE (III) ION, Methane monooxygenase component A alpha chain, Methane monooxygenase component A beta chain, ...
著者Cho, U.S, Kim, B.C.
登録日2021-12-23
公開日2023-01-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase.
Acs Nano, 17, 2023
7T6E
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BU of 7t6e by Molmil
Cryo-EM of NBD-ffsy filaments (class 1)
分子名称: NBD-ffsy peptide
著者Wang, F, Guo, J, Xu, B, Egelman, E.H.
登録日2021-12-13
公開日2023-01-25
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cell spheroid creation by transcytotic intercellular gelation.
Nat Nanotechnol, 18, 2023
5EYX
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BU of 5eyx by Molmil
Monoclinic Form of Centrolobium tomentosum seed lectin (CTL) complexed with Man1-3Man-OMe.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Centrolobium tomentosum lectin, ...
著者Almeida, A.C, Osterne, V.J.S, Santiago, M.Q, Pinto-Junior, V.R, Silva-Filho, J.C, Lossio, C.F, Almeida, R.P.H, Teixeira, C.S, Delatorre, P, Rocha, B.A.M, Santiago, K.S, Cavada, B.S.
登録日2015-11-25
公開日2016-03-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural analysis of Centrolobium tomentosum seed lectin with inflammatory activity.
Arch.Biochem.Biophys., 596, 2016
7TC8
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BU of 7tc8 by Molmil
Cryo-EM structure of methane monooxygenase hydroxylase (by graphene)
分子名称: FE (III) ION, Methane monooxygenase component A alpha chain, Methane monooxygenase component A beta chain, ...
著者Cho, U.S, Kim, B.C.
登録日2021-12-23
公開日2023-01-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase.
Acs Nano, 17, 2023

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件を2024-08-21に公開中

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