PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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7O61	Crystal structure of the C-terminal PASTA domains of Staphylococcus aureus PBP1 分子名称: Penicillin-binding protein 1 著者 Rao, V.A, Lewis, R.J. 登録日 2021-04-09 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structure of the C-terminal PASTA domains of Staphylococcus aureus PBP1 To Be Published
7O2U	PqsR (MvfR) in complex with antagonist 40 分子名称: 2-[4-[(2S)-3-(6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanyl-propoxy]phenoxy]ethanenitrile, LysR family transcriptional regulator 著者 Emsley, J, Richardson, W. 登録日 2021-03-31 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 PqsR (MvfR) in complex with antagonist 40 To Be Published
6MD6	CRYSTAL STRUCTURE ANALYSIS OF PLANT EXOHYDROLASE IN COMPLEX WITH METHYL 2-THIO-BETA-SOPHOROSIDE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-D-glucan exohydrolase isoenzyme ExoI, GLYCEROL, ... 著者 Streltsov, V.A, Luang, S, Hrmova, M. 登録日 2018-09-04 公開日 2019-05-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Discovery of processive catalysis by an exo-hydrolase with a pocket-shaped active site. Nat Commun, 10, 2019
5BZY	X-ray crystal structure of a continuously hydrogen bonded 14mer DNA lattice. 分子名称: DNA (5'-D(*GP*GP*AP*AP*AP*TP*AP*TP*TP*GP*GP*AP*GP*A)-3'), MAGNESIUM ION 著者 Saoji, M, Paukstelis, P.J. 登録日 2015-06-11 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Sequence-dependent structural changes in a self-assembling DNA oligonucleotide. Acta Crystallogr.,Sect.D, 71, 2015
6PIQ	Crystal Structure of EcDsbA in a complex with unpurified reaction product G6 (pyrazole 9) 分子名称: 2-[4-(4-cyano-3-methylphenoxy)phenyl]-N-ethyl-N-[2-(1H-pyrazol-1-yl)ethyl]acetamide, COPPER (II) ION, Thiol:disulfide interchange protein DsbA 著者 Ilyichova, O.V, Bentley, M, Doak, B, Scanlon, M.J. 登録日 2019-06-26 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL X ). J.Med.Chem., 63, 2020
7O5T	Crystal Structure of a Class D Carbapenemase Complexed with Bromide 分子名称: BROMIDE ION, Beta-lactamase 著者 Zhou, Q, He, Y, Jin, Y. 登録日 2021-04-09 公開日 2022-04-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
6MEF	Crystal structure of broadly neutralizing antibody AR3C 分子名称: antibody AR3C Heavy Chain, antibody AR3C Light Chain 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2018-09-06 公開日 2018-11-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe, 24, 2018
7O35	Crystal Structure of SARS-CoV-2 N-CTD in complex with GTP (I) 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Nucleoprotein 著者 Ciges-Tomas, J.R, Vilar, M. 登録日 2021-04-01 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification of a guanine-specific pocket in the protein N of SARS-CoV-2. Commun Biol, 5, 2022
6MES	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1907) 分子名称: 1-[(1H-benzimidazol-2-yl)methyl]-4-[(2,4-dichlorophenyl)methyl]-1,3-dihydro-2H-imidazol-2-one, GLYCEROL, METHIONINE, ... 著者 Barros-Alvarez, X, Hol, W.G.J. 登録日 2018-09-07 公開日 2019-09-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei Rsc Med Chem, 2020
5C19	p97 variant 2 in the apo state 分子名称: SULFATE ION, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2015-06-13 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97. Structure, 24, 2016
6VHI	Crystal structure of the human ILRUN Fw domain 分子名称: Protein ILRUN 著者 Caputo, A.T, Adams, T.E. 登録日 2020-01-09 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Molecular characterisation of ILRUN, a novel inhibitor of proinflammatory and antimicrobial cytokines. Heliyon, 6, 2020
6VHT	Klebsiella oxytoca NpsA N-terminal subdomain in space group C2 分子名称: BROMIDE ION, CHLORIDE ION, NpsA Adenylation Domain 著者 Kreitler, D.F, Gulick, A.M. 登録日 2020-01-10 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca. Acs Infect Dis., 6, 2020
6UTT	LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with calcium 分子名称: ATP-dependent sacrificial sulfur transferase LarE, CALCIUM ION, PHOSPHATE ION, ... 著者 Fellner, M, Huizenga, K, Hausinger, R.P, Hu, J. 登録日 2019-10-29 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE. Sci Rep, 10, 2020
6P08	Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate 分子名称: ADENOSINE MONOPHOSPHATE, Kanamycin nucleotidyltransferase, MAGNESIUM ION, ... 著者 Selvaraj, B, Cuneo, M.J. 登録日 2019-05-16 公開日 2020-01-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 "Catch and Release": a Variation of the Archetypal Nucleotidyl Transfer Reaction Acs Catalysis, 10, 2020
6P0F	N-terminal domain of Thermococcus Gammatolerans McrB 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AMMONIUM ION, GTPase subunit of restriction endonuclease, ... 著者 Hosford, C.J, Chappie, J.S. 登録日 2019-05-17 公開日 2019-12-18 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (1.683 Å) 主引用文献 The structure of theThermococcus gammatoleransMcrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs. J.Biol.Chem., 295, 2020
8Q6M	Human SOD1 low dose data collecton 分子名称: ACETATE ION, COPPER (II) ION, SULFATE ION, ... 著者 Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. 登録日 2023-08-14 公開日 2023-12-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS. Plos Biol., 22, 2024
8Q6F	HUMAN PI4KIIIB IN COMPLEX WITH COVALENTLY BOUND INHIBITOR (COMPOUND 4) 分子名称: 1,2-ETHANEDIOL, 3-(3-fluorosulfonyloxy-4-methoxy-phenyl)-2,5-dimethyl-7-(pyridin-4-ylmethylamino)pyrazolo[1,5-a]pyrimidine, GLYCEROL, ... 著者 Somers, D.O. 登録日 2023-08-11 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.506 Å) 主引用文献 Covalent targeting of non-cysteine residues in PI4KIII beta. Rsc Chem Biol, 4, 2023
6AW1	Crystal structure of CEACAM3 分子名称: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, DI(HYDROXYETHYL)ETHER, ... 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2017-09-05 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA. EMBO J., 37, 2018
6P58	Dark and Steady State-Illuminated Crystal Structure of Cyanobacteriochrome Receptor PixJ at 150K 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Methyl-accepting chemotaxis protein, ... 著者 Clinger, J.A, Miller, M.D, Buirgie, E.S, Vierstra, R.D, Phillips Jr, G.N. 登録日 2019-05-29 公開日 2019-12-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Photoreversible interconversion of a phytochrome photosensory module in the crystalline state. Proc.Natl.Acad.Sci.USA, 117, 2020
8Q7I	PCNA from Chaetomium thermophilum in complex with Fen1 peptide 分子名称: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION 著者 Alphey, M.S, Wolford, C.B, MacNeill, S.A. 登録日 2023-08-16 公開日 2023-12-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA. Front Mol Biosci, 10, 2023
6P0J	Crystal structure of GDP-bound human RalA 分子名称: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Ral-A 著者 Bum-Erdene, K, Gonzalez-Gutierrez, G, Liu, D, Meroueh, S.O. 登録日 2019-05-17 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases. Proc.Natl.Acad.Sci.USA, 117, 2020
6ASO	Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA 分子名称: MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... 著者 Montemayor, E.J, Brow, D.A, Butcher, S.E. 登録日 2017-08-25 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
7O5N	Crystal Structure of a Class D carbapenemase complexed with Avibactam 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1-BUTANOL, Beta-lactamase, ... 著者 Zhou, Q, Zhang, Z, He, Y, Jin, Y. 登録日 2021-04-09 公開日 2022-04-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
6AW6	1.70A resolution structure of catechol O-methyltransferase (COMT) L136M (rhombohedral form) from Nannospalax galili 分子名称: Catechol O-methyltransferase, SULFATE ION 著者 Lovell, S, Mehzabeen, N, Battaile, K.P, Deng, Y, Hanzlik, R.P, Shams, I, Moskovitz, J. 登録日 2017-09-05 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the catechol-o-methyl transferase (COMT) enzyme of the subterranean mole rat (Spalax) and the effect of L136M substitution To be published
6UP5	Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure 分子名称: 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Romero, J.M. 登録日 2019-10-16 公開日 2020-07-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure. Arch.Biochem.Biophys., 689, 2020

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