5NYK
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![BU of 5nyk by Molmil](/molmil-images/mine/5nyk) | Crystal structure of the atypical poplar thioredoxin-like2.1 in oxidized state | 分子名称: | CHLORIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Chibani, K, Saul, F.A, Haouz, A, Rouhier, N. | 登録日 | 2017-05-11 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Structural snapshots along the reaction mechanism of the atypical poplar thioredoxin-like2.1. FEBS Lett., 592, 2018
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5NZ4
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![BU of 5nz4 by Molmil](/molmil-images/mine/5nz4) | Complex of I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pachl, P, Pokorna, J, Karlukova, E. | 登録日 | 2017-05-12 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus. Viruses, 10, 2018
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5A1R
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![BU of 5a1r by Molmil](/molmil-images/mine/5a1r) | |
5O4P
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![BU of 5o4p by Molmil](/molmil-images/mine/5o4p) | Crystal structure of AMPylated GRP78 | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, SULFATE ION | 著者 | Yan, Y, Chen, R, Ron, D, Read, R. | 登録日 | 2017-05-30 | 公開日 | 2017-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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5NU7
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8JJS
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![BU of 8jjs by Molmil](/molmil-images/mine/8jjs) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2023-05-31 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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5NYO
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![BU of 5nyo by Molmil](/molmil-images/mine/5nyo) | Crystal structure of an atypical poplar thioredoxin-like2.1 variant in dimeric form | 分子名称: | SULFATE ION, Thioredoxin-like protein 2.1 | 著者 | Chibani, K, Saul, F.A, Haouz, A, Rouhier, N. | 登録日 | 2017-05-11 | 公開日 | 2018-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural snapshots along the reaction mechanism of the atypical poplar thioredoxin-like2.1. FEBS Lett., 592, 2018
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5NZF
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![BU of 5nzf by Molmil](/molmil-images/mine/5nzf) | Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pachl, P, Pokorna, J. | 登録日 | 2017-05-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus. Viruses, 10, 2018
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5NYN
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![BU of 5nyn by Molmil](/molmil-images/mine/5nyn) | Crystal structure of the atypical poplar thioredoxin-like2.1 in complex with gluathione | 分子名称: | GLUTATHIONE, SULFATE ION, Thioredoxin-like protein 2.1 | 著者 | Chibani, K, Saul, F.A, Haouz, A, Rouhier, N. | 登録日 | 2017-05-11 | 公開日 | 2018-02-28 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural snapshots along the reaction mechanism of the atypical poplar thioredoxin-like2.1. FEBS Lett., 592, 2018
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5O10
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![BU of 5o10 by Molmil](/molmil-images/mine/5o10) | Y48H mutant of human cytochrome c | 分子名称: | Cytochrome c, HEME C | 著者 | Moreno-Chicano, T, Deacon, O.M, Hough, M.A, Worrall, J.A.R. | 登録日 | 2017-05-17 | 公開日 | 2018-03-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Heightened Dynamics of the Oxidized Y48H Variant of Human Cytochrome c Increases Its Peroxidatic Activity. Biochemistry, 56, 2017
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5O27
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5O2T
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![BU of 5o2t by Molmil](/molmil-images/mine/5o2t) | Human KRAS in complex with darpin K27 | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase KRas, MAGNESIUM ION, ... | 著者 | Debreczeni, J.E, Guillard, S, Kolasinska-Zwierz, P, Breed, J, Zhang, J, Bery, N, Marwood, R, Tart, J, Stocki, P, Mistry, B, Phillips, C, Rabbitts, T, Jackson, R, Minter, R. | 登録日 | 2017-05-22 | 公開日 | 2017-07-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange. Nat Commun, 8, 2017
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5O46
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![BU of 5o46 by Molmil](/molmil-images/mine/5o46) | Crystal structure of Iristatin, a secreted salivary cystatin from the hard tick Ixodes ricinus | 分子名称: | GLYCEROL, Iristatin | 著者 | Busa, M, Rezacova, P, Kotal, J, Kotsyfakis, M, Mares, M. | 登録日 | 2017-05-26 | 公開日 | 2018-06-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin. Cell.Mol.Life Sci., 76, 2019
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8IJ9
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![BU of 8ij9 by Molmil](/molmil-images/mine/8ij9) | Crystal structure of the ELKS1/Rab6B complex | 分子名称: | ELKS/Rab6-interacting/CAST family member 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Jin, G, Wei, Z. | 登録日 | 2023-02-26 | 公開日 | 2023-06-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation. J.Biol.Chem., 299, 2023
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5O4W
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![BU of 5o4w by Molmil](/molmil-images/mine/5o4w) | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal | 分子名称: | Lysozyme C | 著者 | Clabbers, M.T.B, van Genderen, E, Wan, W, Wiegers, E.L, Gruene, T, Abrahams, J.P. | 登録日 | 2017-05-31 | 公開日 | 2017-08-23 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.11 Å) | 主引用文献 | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal. Acta Crystallogr D Struct Biol, 73, 2017
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5ARD
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![BU of 5ard by Molmil](/molmil-images/mine/5ard) | Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase | 分子名称: | 5-methyl-2-(5-methylpyridin-2-yl)pyridine, CALCIUM ION, GLYCEROL, ... | 著者 | Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. | 登録日 | 2015-09-24 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase To be Published
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5ARK
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5OAZ
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![BU of 5oaz by Molmil](/molmil-images/mine/5oaz) | |
5OBU
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![BU of 5obu by Molmil](/molmil-images/mine/5obu) | Mycoplasma genitalium DnaK deletion mutant lacking SBDalpha in complex with AMPPNP. | 分子名称: | Chaperone protein DnaK, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Adell, M, Calisto, B, Fita, I, Martinelli, L. | 登録日 | 2017-06-29 | 公開日 | 2018-05-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone. Protein Sci., 27, 2018
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5OC5
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5NZN
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![BU of 5nzn by Molmil](/molmil-images/mine/5nzn) | Complex of H275Y/S247N mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pachl, P, Pokorna, J. | 登録日 | 2017-05-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus. Viruses, 10, 2018
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5NUK
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![BU of 5nuk by Molmil](/molmil-images/mine/5nuk) | Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP) | 分子名称: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Beta-lactoglobulin, CHLORIDE ION, ... | 著者 | Loch, J.I, Bonarek, P, Tworzydlo, M, Lazinska, I, Szydlowska, J, Lewinski, K. | 登録日 | 2017-04-30 | 公開日 | 2018-04-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The engineered beta-lactoglobulin with complementarity to the chlorpromazine chiral conformers. Int. J. Biol. Macromol., 114, 2018
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5OGH
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![BU of 5ogh by Molmil](/molmil-images/mine/5ogh) | Structure of RNase A at high resolution (1.16 A) in complex with 3'-CMP and sulphate ions | 分子名称: | CHLORIDE ION, CYTIDINE-3'-MONOPHOSPHATE, Ribonuclease pancreatic, ... | 著者 | Blanco, J.A, Prats-Ejarque, G, Salazar, V.A, Moussaoui, M, Boix, E. | 登録日 | 2017-07-13 | 公開日 | 2018-08-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates. Biochim Biophys Acta Gen Subj, 1863, 2019
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5NZE
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![BU of 5nze by Molmil](/molmil-images/mine/5nze) | Complex of S247N mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pachl, P, Pokorna, J, Hejdanek, J. | 登録日 | 2017-05-13 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus. Viruses, 10, 2018
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5EAG
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![BU of 5eag by Molmil](/molmil-images/mine/5eag) | Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor Prochloraz | 分子名称: | Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, Prochloraz | 著者 | Tyndall, J.D.A, Sabherwal, M, Sagatova, A.A, Keniya, M.V, Wilson, R.K, Woods, M.V, Monk, B.C. | 登録日 | 2015-10-16 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and Functional Elucidation of Yeast Lanosterol 14 alpha-Demethylase in Complex with Agrochemical Antifungals. PLoS ONE, 11, 2016
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