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1T36
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Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Carbamoyl-phosphate synthase large chain, ...
著者Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
登録日2004-04-24
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Long-range allosteric transitions in carbamoyl phosphate synthetase.
Protein Sci., 13, 2004
1LXK
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Streptococcus pneumoniae Hyaluronate Lyase in Complex with Tetrasaccharide Hyaluronan Substrate
分子名称: Hyaluronate Lyase, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Jedrzejas, M.J, Mello, L.V, De Groot, B.L, Li, S.
登録日2002-06-05
公開日2002-08-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
J.Biol.Chem., 277, 2002
1J71
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Structure of the extracellular aspartic proteinase from Candida tropicalis yeast.
分子名称: Aspartic proteinase, ETHANOL, Tetrapeptide Thr-Ile-Thr-Ser
著者Symersky, J, Monod, M, Foundling, S.I.
登録日2001-05-15
公開日2001-05-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution structure of the extracellular aspartic proteinase from Candida tropicalis yeast.
Biochemistry, 36, 1997
7EHO
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Chitin oligosaccharide binding protein
分子名称: Chitin oligosaccharide binding protein NagB2, TETRAETHYLENE GLYCOL
著者Itoh, T, Hibi, T, Kimoto, H.
登録日2021-03-30
公開日2021-07-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural characterization of two solute-binding proteins for N,N' -diacetylchitobiose/ N,N',N'' -triacetylchitotoriose of the gram-positive bacterium, Paenibacillus sp. str. FPU-7.
J Struct Biol X, 5, 2021
7VPL
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Cryo-EM structure of the human ATP13A2 (SPM-bound E2Pi state)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ...
著者Tomita, A, Yamashita, K, Nishizawa, T, Nureki, O.
登録日2021-10-17
公開日2021-12-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM reveals mechanistic insights into lipid-facilitated polyamine export by human ATP13A2.
Mol.Cell, 81, 2021
7VSH
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Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in E1P state.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, MAGNESIUM ION, ...
著者Nakanishii, H, Abe, K.
登録日2021-10-26
公開日2021-12-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2.
J.Biol.Chem., 298, 2022
7VPJ
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Cryo-EM structure of the human ATP13A2 (E1P-ADP state)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Tomita, A, Yamashita, K, Nishizawa, T, Nureki, O.
登録日2021-10-17
公開日2021-12-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM reveals mechanistic insights into lipid-facilitated polyamine export by human ATP13A2.
Mol.Cell, 81, 2021
2LWZ
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BU of 2lwz by Molmil
NMR Structures of Single-chain Insulin
分子名称: SINGLE-CHAIN INSULIN
著者Weiss, M.A, Yang, Y.
登録日2012-08-09
公開日2013-08-28
実験手法SOLUTION NMR
主引用文献Dynamic repair of an amyloidogenic protein: Insulin fibrillation is blocked by tethering a nascent alpha-helix
To be Published
5OT0
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BU of 5ot0 by Molmil
The thermostable L-asparaginase from Thermococcus kodakarensis
分子名称: 1,2-ETHANEDIOL, L-asparaginase, PHOSPHATE ION, ...
著者Guo, J, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Chohan, S.M, Akhtar, M.
登録日2017-08-18
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structure and function of the thermostable L-asparaginase from Thermococcus kodakarensis.
Acta Crystallogr D Struct Biol, 73, 2017
7VGV
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Anion free form of light-driven chloride ion-pumping rhodopsin, NM-R3, structure determined by serial femtosecond crystallography at SACLA
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, HEXADECANE, ...
著者Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M.
登録日2021-09-18
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 119, 2022
5OV3
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Structure of the RbBP5 beta-propeller domain
分子名称: Retinoblastoma-binding protein 5, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
著者Mittal, A, Zhang, Y, Gamblin, S.J, Wilson, J.R.
登録日2017-08-27
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structure of the RbBP5 beta-propeller domain reveals a surface with potential nucleic acid binding sites.
Nucleic Acids Res., 46, 2018
7VW7
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BU of 7vw7 by Molmil
Crystal structure of the 2 ADP-AlF4-bound V1 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Suzuki, K, Shekhar, M, Gupta, C, Singharoy, A, Murata, T.
登録日2021-11-09
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.818 Å)
主引用文献Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations.
Acs Cent.Sci., 8, 2022
7V5S
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BU of 7v5s by Molmil
Crystal structure of human bleomycin hydrolase C73A mutant
分子名称: Bleomycin hydrolase, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
著者Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C.
登録日2021-08-18
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
7EE5
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Crystal structure of Neu5Gc bound PltC
分子名称: N-glycolyl-alpha-neuraminic acid, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, Subtilase cytotoxin subunit B-like protein, ...
著者Liu, X.Y, Chen, Z, Gao, X.
登録日2021-03-17
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
7EE4
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Crystal structure of Neu5Ac bound PltC
分子名称: N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Liu, X.Y, Chen, Z, Gao, X.
登録日2021-03-17
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
7EE3
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Crystal structure of PltC
分子名称: Subtilase cytotoxin subunit B-like protein, TETRAETHYLENE GLYCOL
著者Liu, X.Y, Chen, Z, Gao, X.
登録日2021-03-17
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
7E6E
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BU of 7e6e by Molmil
Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in D-cycloserine-inhibition
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6A
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BU of 7e6a by Molmil
Crystal structure of cysteine desulfurase SufS C361A from Bacillus subtilis
分子名称: 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6C
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Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS C361A from Bacillus subtilis
分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6B
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BU of 7e6b by Molmil
Crystal structure of PMP-bound form of cysteine desulfurase SufS C361A from Bacillus subtilis
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7DU3
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BU of 7du3 by Molmil
ThiL in complex with AMP-PNP
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Lin, J.Q, Lescar, J.
登録日2021-01-07
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献ThiL in complex with AMP-PNP
To Be Published
7ESF
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The Crystal Structure of human MTH1 from Biortus
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL
著者Wang, F, Cheng, W, Shang, H, Wang, R, Zhang, B, Tian, F.
登録日2021-05-10
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Crystal Structure of human MTH1 from Biortus
To Be Published
7ET1
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Cryo-EM structure of the gastric proton pump K791S/E820D/Y340N/E936V/Y799W mutant in K+-occluded (K+)E2-AlF state
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Abe, K.
登録日2021-05-12
公開日2021-09-01
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Gastric proton pump with two occluded K + engineered with sodium pump-mimetic mutations.
Nat Commun, 12, 2021
2LXD
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BU of 2lxd by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments for LMO2(LIM2)-Ldb1(LID)
分子名称: Rhombotin-2,LIM domain-binding protein 1, ZINC ION
著者Dastmalchi, S, Wilkinson-White, L, Kwan, A.H, Gamsjaeger, R, Mackay, J.P, Matthews, J.M.
登録日2012-08-20
公開日2012-09-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex.
Protein Sci., 21, 2012
5QJ1
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CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 L30S NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 6-(ethylamino)-2-(4-fluorophenyl)-5-(3-{[1-(5-fluoropyrimidin-2-yl)cyclopropyl]carbamoyl}-4-methoxyphenyl)-N-methyl-1-benzofuran-3-carboxamide
分子名称: 6-(ethylamino)-2-(4-fluorophenyl)-5-(3-{[1-(5-fluoropyrimidin-2-yl)cyclopropyl]carbamoyl}-4-methoxyphenyl)-N-methyl-1-benzofuran-3-carboxamide, GLYCEROL, RNA-dependent RNA polymerase, ...
著者Sheriff, S.
登録日2018-08-13
公開日2018-11-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors.
ACS Med Chem Lett, 9, 2018

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件を2024-07-17に公開中

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