PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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5N4Q	Human myelin protein P2, mutant T51P 分子名称: D-MALATE, Myelin P2 protein, PALMITIC ACID, ... 著者 Ruskamo, S, Kursula, P. 登録日 2017-02-11 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. Sci Rep, 7, 2017
5N70	CRYSTAL STRUCTURE OF MATURE CATHEPSIN D FROM THE TICK IXODES RICINUS (IRCD1) IN COMPLEX WITH THE N-TERMINAL OCTAPEPTIDE OF THE PROPEPTID 分子名称: ALA-PHE-ARG-ILE-PRO-LEU-THR-ARG, Putative cathepsin d 著者 Brynda, J, Hanova, I, Hobizalova, R, Mares, M. 登録日 2017-02-17 公開日 2017-12-27 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite. Cell Chem Biol, 25, 2018
5N7N	CRYSTAL STRUCTURE OF CATHEPSIN D ZYMOGEN FROM THE TICK IXODES RICINUS (IRCD1) 分子名称: AMMONIUM ION, Putative cathepsin d, SULFATE ION 著者 Brynda, J, Hanova, I, Hobizalova, R, Mares, M. 登録日 2017-02-21 公開日 2017-12-27 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite. Cell Chem Biol, 25, 2018
5N8L	Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex B) 分子名称: RISC-loading complex subunit TARBP2, RNA (5'-R(*GP*UP*AP*CP*GP*GP*AP*AP*UP*AP*GP*AP*UP*AP*AP*UP*UP*AP*AP*UP*U)-3'), RNA (5'-R(*UP*UP*AP*AP*UP*UP*AP*UP*CP*UP*AP*UP*UP*CP*CP*GP*UP*AP*CP*UP*U)-3') 著者 Masliah, G, Maris, C, Allain, H.-T.F. 登録日 2017-02-23 公開日 2018-02-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains. EMBO J., 37, 2018
5DDQ	L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ 分子名称: GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5DF6	Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide 分子名称: Tyrosine-protein phosphatase non-receptor type 11, UNKNOWN ATOM OR ION, txnip 著者 Dong, A, Li, W, Tempel, W, Liu, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-08-26 公開日 2015-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. Biochem.J., 473, 2016
5NOL	Ca2+-induced Movement of Tropomyosin on Native Cardiac Thin Filaments - "Closed" state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cardiac muscle alpha actin 1, MAGNESIUM ION, ... 著者 Risi, C, Eisner, J, Belknap, B, Heeley, D.H, White, H.D, Schroeder, G.F, Galkin, V.E. 登録日 2017-04-12 公開日 2017-07-19 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Ca(2+)-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8JRL	Crystal structure of P450 TleB with an indole alkaloid 分子名称: (2~{S})-~{N}-[(2~{S})-1-(4-fluoranyl-1~{H}-indol-3-yl)-3-oxidanyl-propan-2-yl]-3-methyl-2-sulfanyl-butanamide, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, J, Yan, W.P. 登録日 2023-06-17 公開日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Regulation of P450 TleB catalytic flow for the synthesis of sulfur-containing indole alkaloids by substrate structure-directed strategy. and protein engineering. Sci China Chem, 66, 2023
5DGU	Crystal Structure of HIV-1 Protease Inhibitors Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand GRL-004-11A 分子名称: (3R,3aR,4S,7aS)-3-methoxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... 著者 Agniswamy, J, Wang, Y.-F, Weber, I.T. 登録日 2015-08-28 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands. Org.Biomol.Chem., 13, 2015
5DI3	Crystal structure of Arl13B in complex with Arl3 of Chlamydomonas reinhardtii 分子名称: ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 3, MAGNESIUM ION, ... 著者 Gotthardt, K, Lokaj, M, Falk, N, Koerner, C, Giessl, A, Wittinghofer, A. 登録日 2015-08-31 公開日 2015-11-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins. Elife, 4, 2015
5DDR	L-glutamine riboswitch bound with L-glutamine soaked with Cs+ 分子名称: CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5DE3	The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp 分子名称: ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER 著者 Gotthardt, K, Lokaj, M, Wittinghofer, A. 登録日 2015-08-25 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.417 Å) 主引用文献 The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp To Be Published
5DJ7	S. erythraea trypsin acyl-enzyme 分子名称: Trypsin 著者 Blankenship, E, Lodowski, D.T. 登録日 2015-09-01 公開日 2017-03-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (0.87 Å) 主引用文献 High resolution structures of S. erythraeus trypsin throughout the catalytic cycle To be Published
5DFS	Crystal structure of Spider Monkey Cytochrome C at 1.15 Angstrom 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome c, ... 著者 MOU, T.C, McClelland, L.J, Jeakins-Cooley, M.E, Goldes, M.E, SPRANG, S.R, BOWLER, B.E. 登録日 2015-08-27 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Disruption of a hydrogen bond network in human versus spider monkey cytochrome c affects heme crevice stability. J.Inorg.Biochem., 158, 2016
8JUP	Crystal structure of a receptor like kinase from rice 分子名称: ADENOSINE-5'-TRIPHOSPHATE, LRR receptor-like serine/threonine-protein kinase FLS2, MAGNESIUM ION 著者 Ming, Z, Zhao, Q. 登録日 2023-06-27 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 An Active State Formation Mechanism of Receptor Kinase in Plant Plant Commun., 2024
5NU2	Structure of non-fluorescent human urine RBP4 分子名称: CHLORIDE ION, PALMITIC ACID, Retinol-binding protein 4 著者 Perduca, M, Monaco, H.L, Galliano, M. 登録日 2017-04-28 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Human plasma retinol-binding protein (RBP4) is also a fatty acid-binding protein. Biochim. Biophys. Acta, 1863, 2018
8LYZ	AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME 分子名称: HEN EGG WHITE LYSOZYME 著者 Beddell, C.R, Blake, C.C.F, Oatley, S.J. 登録日 1977-09-16 公開日 1977-10-24 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An x-ray study of the structure and binding properties of iodine-inactivated lysozyme. J.Mol.Biol., 97, 1975
5NUA	Structure of human urine RBP4 saturated with laurate 分子名称: CHLORIDE ION, LAURIC ACID, Retinol-binding protein 4 著者 Perduca, M, Monaco, H.L, Galliano, M. 登録日 2017-04-28 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Human plasma retinol-binding protein (RBP4) is also a fatty acid-binding protein. Biochim. Biophys. Acta, 1863, 2018
8LPR	STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS 分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION 著者 Fujishige, A, Bone, R, Agard, D.A. 登録日 1991-08-05 公開日 1993-01-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991
5NUN	Engineered beta-lactoglobulin: variant F105L-L39A-M107F in complex with chlorpromazine (LG-LAF-CLP) 分子名称: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Beta-lactoglobulin 著者 Loch, J.I, Bonarek, P, Towrzydlo, M, Lazinskia, I, Szydlowska, J, Lewinski, K. 登録日 2017-04-30 公開日 2018-04-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The engineered beta-lactoglobulin with complementarity to the chlorpromazine chiral conformers. Int. J. Biol. Macromol., 114, 2018
8KFP	Solution structure of Drosophila melanogaster R2D2 dsRBD1 分子名称: R2D2 著者 Aute, R, Deshmukh, M.V. 登録日 2023-08-16 公開日 2024-06-26 実験手法 SOLUTION NMR 主引用文献 Key arginine residues in R2D2 dsRBD1 and dsRBD2 lead the siRNA recognition in Drosophila melanogaster RNAi pathway. Biophys.Chem., 310, 2024
5BRY	HIV-1 wild Type protease with GRL-011-11A (a methylamine bis-Tetrahydrofuran P2-Ligand, sulfonamide isostere derivate) 分子名称: (3R,3aS,4R,6aR)-4-(methylamino)hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Protease, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2015-06-01 公開日 2015-09-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Design of HIV-1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Studies. J.Med.Chem., 58, 2015
5LWR	Endothiapepsin in complex with a derivative of fragment 177 分子名称: 1,2-ETHANEDIOL, 4-[12-[(1-chloranyl-5,6,7-trimethyl-pyrrolo[3,4-d]pyridazin-3-ium-3-yl)methyl]-10,11-dimethyl-3,4,6,7,11-pentazatricyclo[7.3.0.0^{2,6}]dodeca-1(12),2,4,7,9-pentaen-5-yl]-1,2,5-trimethyl-pyrrole-3-carbaldehyde, ACETATE ION, ... 著者 Ehrmann, F.R, Schiebel, J, Heine, A, Klebe, G. 登録日 2016-09-19 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.249 Å) 主引用文献 A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red Herring. Angew. Chem. Int. Ed. Engl., 56, 2017
5ARC	Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase 分子名称: 5-methyl-2-(5-methylpyridin-2-yl)pyridine, CALCIUM ION, GLYCEROL, ... 著者 Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. 登録日 2015-09-24 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase To be Published
5LKV	Dehaloperoxidase B from Amphitrite ornata: imidazole complex 分子名称: Dehaloperoxidase B, GLYCEROL, IMIDAZOLE, ... 著者 Chicano, T.M, Dworkowski, F.S.N, Hough, M.A. 登録日 2016-07-25 公開日 2017-08-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Dehaloperoxidase B from Amphitrite ornata: imidazole complex to be published

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