9BJK
 
 | | Inactive mu opioid receptor bound to Nb6, naloxone and NAM | | 分子名称: | Mu-type opioid receptor, Naloxone, Nalpha-[({(1M)-1-[5-(benzyloxy)pyridin-3-yl]naphthalen-2-yl}sulfanyl)acetyl]-3-methoxy-N,4-dimethyl-L-phenylalaninamide, ... | | 著者 | O'Brien, E.S, Wang, H, Kaavya Krishna, K, Zhang, C, Kobilka, B.K. | | 登録日 | 2024-04-25 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | A mu-opioid receptor modulator that works cooperatively with naloxone.
Nature, 631, 2024
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9EZ1
 | | Vitamin D receptor in complex with 1,4a,25-trihydroxyvitamin D3 | | 分子名称: | 1,4a,25-trihydroxyvitamin D3, ACETATE ION, Nuclear receptor coactivator 2, ... | | 著者 | Rochel, N. | | 登録日 | 2024-04-10 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | 4-Hydroxy-1 alpha ,25-Dihydroxyvitamin D 3 : Synthesis and Structure-Function Study.
Biomolecules, 14, 2024
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9C9Y
 | | Human TOP3B-TDRD3 core complex in DNA pre-cleavage state | | 分子名称: | DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*T)-3'), DNA topoisomerase 3-beta-1, MANGANESE (II) ION, ... | | 著者 | Yang, X, Chen, X, Yang, W, Pommier, Y. | | 登録日 | 2024-06-16 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics
To Be Published
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3LTC
 | | X-ray structure of a non-biological ATP binding protein determined in the presence of 10 mM ATP at 2.0 A by multi-wavelength anomalous dispersion | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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9B5W
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9FIJ
 | | Crystal Structure of reduced NuoEF variant E222K(NuoF) from Aquifex aeolicus | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | | 登録日 | 2024-05-29 | | 公開日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I).
Biochim Biophys Acta Bioenerg, 1865, 2024
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3LTU
 | | 5-SeMe-dU containing DNA 8mer | | 分子名称: | 5'-D(*GP*(UMS)P*GP*(T5S)P*AP*CP*AP*C)-3' | | 著者 | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | | 登録日 | 2010-02-16 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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9CK0
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8Y0F
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8YFJ
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3LW1
 | | Binary complex of 14-3-3 sigma and p53 pT387-peptide | | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... | | 著者 | Schumacher, B, Mondry, J, Thiel, P, Weyand, M, Ottmann, C. | | 登録日 | 2010-02-23 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer
Febs Lett., 584, 2010
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9FBV
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9G2A
 | | Staphylococcus aureus MazF in complex with nanobody 4 | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoribonuclease MazF, ... | | 著者 | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | | 登録日 | 2024-07-10 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.046594 Å) | | 主引用文献 | Staphylococcus aureus MazF in complex with nanobody 4.
To Be Published
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9B5P
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9FGQ
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9IIX
 | | A Cryo-EM structure of Bitter taste receptor TAS2R14 with Ggust | | 分子名称: | 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Yuan, Q, Duan, J, Tao, L, Xu, E.H. | | 登録日 | 2024-06-21 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist.
Cell Res., 2024
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9CA0
 | | Human TOP3B-TDRD3 core complex in DNA pre-cleavage state | | 分子名称: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | | 著者 | Yang, X, Chen, X, Yang, W, Pommier, Y. | | 登録日 | 2024-06-16 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics
To Be Published
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3LUN
 | | Structure of ulilysin mutant M290C | | 分子名称: | ARGININE, CALCIUM ION, GLYCEROL, ... | | 著者 | Tallant, C, Garcia-Castellanos, R, Baumann, U, Gomis-Ruth, F.X. | | 登録日 | 2010-02-18 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | On the relevance of the Met-turn methionine in metzincins.
J.Biol.Chem., 285, 2010
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8YTN
 | | Single-chain Fv antibody of E11 | | 分子名称: | GLYCEROL, Single-chain Fv antibody of E11 | | 著者 | Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M. | | 登録日 | 2024-03-26 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Affinity-matured antibody with a disulfide bond in H-CDR3 loop.
Arch.Biochem.Biophys., 758, 2024
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9B5R
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9EZ2
 | | Vitamin D receptor complex with 1,4b,25-trihydroxyvitamin D3 | | 分子名称: | 1,4b,25-trihydroxyvitamin D3, ACETATE ION, Nuclear receptor coactivator 2, ... | | 著者 | Rochel, N. | | 登録日 | 2024-04-10 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | 4-Hydroxy-1 alpha ,25-Dihydroxyvitamin D 3 : Synthesis and Structure-Function Study.
Biomolecules, 14, 2024
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6QQD
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9C9M
 | | HIV-1 intasome core bound with DTG | | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, Integrase, MAGNESIUM ION, ... | | 著者 | Li, M, Craigie, R. | | 登録日 | 2024-06-14 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (2.01 Å) | | 主引用文献 | HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration.
Viruses, 16, 2024
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8XIO
 | | Structure of L797591-SSTR1 G protein complex | | 分子名称: | (2~{S})-~{N}-[(4~{S})-6-azanyl-2,2,4-trimethyl-hexyl]-3-naphthalen-1-yl-2-[[2-phenylethyl(2-pyridin-2-ylethyl)carbamoyl]amino]propanamide, G-alpha-i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | 登録日 | 2023-12-19 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
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9C4O
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