PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

---

3R3Z	Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/Glycolate 分子名称: Fluoroacetate dehalogenase, GLYCOLIC ACID, NICKEL (II) ION 著者 Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. 登録日 2011-03-16 公開日 2011-05-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mapping the reaction coordinates of enzymatic defluorination. J.Am.Chem.Soc., 133, 2011
3G9L	JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-styrylindolin-2-one 分子名称: (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime, Mitogen-activated protein kinase 10 著者 Jacobs, M.D. 登録日 2009-02-13 公開日 2009-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3R7D	Crystal Structure of Unliganded Aspartate Transcarbamoylase from Bacillus subtilis 分子名称: Aspartate carbamoyltransferase, PHOSPHATE ION 著者 Puleo, D.E, Harris, K.M, Cockrell, G.M, Kantrowitz, E.R. 登録日 2011-03-22 公開日 2011-06-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.196 Å) 主引用文献 Crystallographic Snapshots of the Complete Catalytic Cycle of the Unregulated Aspartate Transcarbamoylase from Bacillus subtilis. J.Mol.Biol., 411, 2011
2PVN	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: Casein kinase II subunit alpha, N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
3R7R	Structure-based design of thienobenzoxepin inhibitors of PI3-Kinase 分子名称: 8-(acetylamino)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carboxamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Murray, J.M, Wiesmann, C. 登録日 2011-03-22 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-based design of thienobenzoxepin inhibitors of PI3-kinase. Bioorg.Med.Chem.Lett., 21, 2011
3R7X	Crystal Structure Analysis of a Quinazolinedione sulfonamide bound to human GluR2: A Novel Class of Competitive AMPA Receptor Antagonists with Oral Activity 分子名称: GLUTAMIC ACID, Glutamate receptor 2, N-[6-(1H-imidazol-1-yl)-7-nitro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]methanesulfonamide 著者 Kallen, J. 登録日 2011-03-23 公開日 2011-05-18 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Quinazolinedione sulfonamides: A novel class of competitive AMPA receptor antagonists with oral activity. Bioorg.Med.Chem.Lett., 21, 2011
2PXE	Variant 4 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle 分子名称: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein 著者 Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S. 登録日 2007-05-14 公開日 2007-08-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure, 15, 2007
3FZ1	Crystal structure of a benzthiophene inhibitor bound to human Cyclin-dependent Kinase-2 (CDK-2) 分子名称: (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one, Cell division protein kinase 2 著者 Kurumbail, R.G, Caspers, N. 登録日 2009-01-23 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency. Bioorg.Med.Chem.Lett., 19, 2009
3R9G	Crystal structure of Microcin C7 self immunity acetyltransferase MccE in complex with Coenzyme A and processed Microcin C7 antibiotic 分子名称: 5'-O-[(R)-[(N-acetyl-L-alpha-aspartyl)amino](3-aminopropoxy)phosphoryl]adenosine, COENZYME A, MccE protein 著者 Nair, S.K, Agarwal, V. 登録日 2011-03-25 公開日 2011-04-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Basis for Microcin C7 Inactivation by the MccE Acetyltransferase. J.Biol.Chem., 286, 2011
2PVH	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: Casein kinase II subunit alpha, N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
3G1B	The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide 分子名称: 10-residue peptide, ATP-dependent Clp protease adapter protein clpS, MAGNESIUM ION 著者 Baker, T.A, Roman-Hernandez, G, Sauer, R.T, Grant, R.A. 登録日 2009-01-29 公開日 2009-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.448 Å) 主引用文献 Molecular basis of substrate selection by the N-end rule adaptor protein ClpS. Proc.Natl.Acad.Sci.USA, 106, 2009
2PXV	Variant 6 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle 分子名称: 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein 著者 Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S. 登録日 2007-05-14 公開日 2007-08-07 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure, 15, 2007
2PZX	Structure of the methuselah ectodomain with peptide inhibitor 分子名称: G-protein coupled receptor Mth 著者 West Jr, A.P, Ja, W.W, Delker, S.L, Bjorkman, P.J, Benzer, S, Roberts, R.W. 登録日 2007-05-18 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor. Nat.Chem.Biol., 3, 2007
2Q0E	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase 著者 Stagno, J, Luecke, H. 登録日 2007-05-21 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc.Natl.Acad.Sci.Usa, 104, 2007
3RC6	Molecular mechanisms of viral and host-cell substrate recognition by HCV NS3/4A protease 分子名称: NS3/4A, ZINC ION 著者 Schiffer, C.A, Romano, K.P. 登録日 2011-03-30 公開日 2011-05-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease. J.Virol., 85, 2011
3GDU	Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YRF peptide 分子名称: DegS protease, YRF peptide 著者 Sohn, J, Grant, R.A, Sauer, R.T. 登録日 2009-02-24 公開日 2009-03-31 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism. Structure, 17, 2009
2Q0D	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase 著者 Stagno, J, Luecke, H. 登録日 2007-05-21 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q8G	Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 分子名称: 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 著者 Kato, M, Li, J, Chuang, J.L, Chuang, D.T. 登録日 2007-06-10 公開日 2007-07-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
3GG2	Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate 分子名称: Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID 著者 Bonanno, J.B, Freeman, J, Bain, K.T, Chang, S, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-02-27 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate To be Published
3G87	Crystal structure of malonyl CoA-acyl carrier protein transacylase from Burkholderia pseudomallei using dried seaweed as nucleant or protease 分子名称: Malonyl CoA-acyl carrier protein transacylase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-02-11 公開日 2009-02-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of malonyl CoA-acyl carrier protein transacylase from Burkholderia pseudomallei using dried seaweed as nucleant or protease To be Published
2PNW	Crystal structure of membrane-bound lytic murein transglycosylase from Agrobacterium tumefaciens 分子名称: Membrane-bound lytic murein transglycosylase, SULFATE ION 著者 Bonanno, J.B, Dickey, M, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-04-25 公開日 2007-05-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of membrane-bound lytic murein transglycosylase from Agrobacterium tumefaciens. To be Published
3G9N	JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-phenylindolin-2-one 分子名称: (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime, Mitogen-activated protein kinase 10 著者 Jacobs, M.D. 登録日 2009-02-13 公開日 2009-02-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3GJB	CytC3 with Fe(II) and alpha-ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, ACETATE ION, CytC3, ... 著者 Wong, C, Drennan, C.L. 登録日 2009-03-08 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis of an open active site conformation of nonheme iron halogenase CytC3 J.Am.Chem.Soc., 131, 2009
2PQK	X-ray crystal structure of human Mcl-1 in complex with Bim BH3 分子名称: Bim BH3 peptide, Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ... 著者 Bare, E, Grant, R.A, Keating, A.E. 登録日 2007-05-02 公開日 2007-06-19 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes. Protein Sci., 19, 2010
2Q6J	Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand 分子名称: 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL, Estrogen receptor, GRIP peptide 著者 Zhou, H, Nettles, K.W, Bruning, J.B, Kim, Y, Joachimiak, A, Sharma, S, Carlson, K.E, Stossi, F, Katzenellenbogen, B.S, Greene, G.L, Katzenellenbogen, J.A. 登録日 2007-06-05 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands Chem.Biol., 14, 2007

<554555556557558559560561562563564565566567568569>