3R3Z
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![BU of 3r3z by Molmil](/molmil-images/mine/3r3z) | Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - WT/Glycolate | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID, NICKEL (II) ION | 著者 | Chan, P.W.Y, Yakunin, A.F, Edwards, E.A, Pai, E.F. | 登録日 | 2011-03-16 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mapping the reaction coordinates of enzymatic defluorination. J.Am.Chem.Soc., 133, 2011
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3G9L
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3R7D
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![BU of 3r7d by Molmil](/molmil-images/mine/3r7d) | Crystal Structure of Unliganded Aspartate Transcarbamoylase from Bacillus subtilis | 分子名称: | Aspartate carbamoyltransferase, PHOSPHATE ION | 著者 | Puleo, D.E, Harris, K.M, Cockrell, G.M, Kantrowitz, E.R. | 登録日 | 2011-03-22 | 公開日 | 2011-06-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Crystallographic Snapshots of the Complete Catalytic Cycle of the Unregulated Aspartate Transcarbamoylase from Bacillus subtilis. J.Mol.Biol., 411, 2011
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2PVN
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![BU of 2pvn by Molmil](/molmil-images/mine/2pvn) | Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 | 分子名称: | Casein kinase II subunit alpha, N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE | 著者 | Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. | 登録日 | 2007-05-09 | 公開日 | 2008-05-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
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3R7R
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![BU of 3r7r by Molmil](/molmil-images/mine/3r7r) | Structure-based design of thienobenzoxepin inhibitors of PI3-Kinase | 分子名称: | 8-(acetylamino)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carboxamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 著者 | Murray, J.M, Wiesmann, C. | 登録日 | 2011-03-22 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure-based design of thienobenzoxepin inhibitors of PI3-kinase. Bioorg.Med.Chem.Lett., 21, 2011
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3R7X
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2PXE
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![BU of 2pxe by Molmil](/molmil-images/mine/2pxe) | Variant 4 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle | 分子名称: | 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein | 著者 | Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S. | 登録日 | 2007-05-14 | 公開日 | 2007-08-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure, 15, 2007
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3FZ1
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![BU of 3fz1 by Molmil](/molmil-images/mine/3fz1) | Crystal structure of a benzthiophene inhibitor bound to human Cyclin-dependent Kinase-2 (CDK-2) | 分子名称: | (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one, Cell division protein kinase 2 | 著者 | Kurumbail, R.G, Caspers, N. | 登録日 | 2009-01-23 | 公開日 | 2009-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency. Bioorg.Med.Chem.Lett., 19, 2009
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3R9G
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2PVH
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![BU of 2pvh by Molmil](/molmil-images/mine/2pvh) | Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 | 分子名称: | Casein kinase II subunit alpha, N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE | 著者 | Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. | 登録日 | 2007-05-09 | 公開日 | 2008-05-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
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3G1B
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![BU of 3g1b by Molmil](/molmil-images/mine/3g1b) | The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide | 分子名称: | 10-residue peptide, ATP-dependent Clp protease adapter protein clpS, MAGNESIUM ION | 著者 | Baker, T.A, Roman-Hernandez, G, Sauer, R.T, Grant, R.A. | 登録日 | 2009-01-29 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | 主引用文献 | Molecular basis of substrate selection by the N-end rule adaptor protein ClpS. Proc.Natl.Acad.Sci.USA, 106, 2009
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2PXV
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![BU of 2pxv by Molmil](/molmil-images/mine/2pxv) | Variant 6 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle | 分子名称: | 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein | 著者 | Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S. | 登録日 | 2007-05-14 | 公開日 | 2007-08-07 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure, 15, 2007
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2PZX
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![BU of 2pzx by Molmil](/molmil-images/mine/2pzx) | Structure of the methuselah ectodomain with peptide inhibitor | 分子名称: | G-protein coupled receptor Mth | 著者 | West Jr, A.P, Ja, W.W, Delker, S.L, Bjorkman, P.J, Benzer, S, Roberts, R.W. | 登録日 | 2007-05-18 | 公開日 | 2007-08-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor. Nat.Chem.Biol., 3, 2007
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2Q0E
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3RC6
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3GDU
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2Q0D
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2Q8G
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![BU of 2q8g by Molmil](/molmil-images/mine/2q8g) | Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 | 分子名称: | 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | 著者 | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | 登録日 | 2007-06-10 | 公開日 | 2007-07-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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3GG2
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![BU of 3gg2 by Molmil](/molmil-images/mine/3gg2) | Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate | 分子名称: | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Chang, S, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-02-27 | 公開日 | 2009-03-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate To be Published
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3G87
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2PNW
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![BU of 2pnw by Molmil](/molmil-images/mine/2pnw) | Crystal structure of membrane-bound lytic murein transglycosylase from Agrobacterium tumefaciens | 分子名称: | Membrane-bound lytic murein transglycosylase, SULFATE ION | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2007-04-25 | 公開日 | 2007-05-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of membrane-bound lytic murein transglycosylase from Agrobacterium tumefaciens. To be Published
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3G9N
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3GJB
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2PQK
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![BU of 2pqk by Molmil](/molmil-images/mine/2pqk) | X-ray crystal structure of human Mcl-1 in complex with Bim BH3 | 分子名称: | Bim BH3 peptide, Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ... | 著者 | Bare, E, Grant, R.A, Keating, A.E. | 登録日 | 2007-05-02 | 公開日 | 2007-06-19 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes. Protein Sci., 19, 2010
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2Q6J
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![BU of 2q6j by Molmil](/molmil-images/mine/2q6j) | Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand | 分子名称: | 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL, Estrogen receptor, GRIP peptide | 著者 | Zhou, H, Nettles, K.W, Bruning, J.B, Kim, Y, Joachimiak, A, Sharma, S, Carlson, K.E, Stossi, F, Katzenellenbogen, B.S, Greene, G.L, Katzenellenbogen, J.A. | 登録日 | 2007-06-05 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands Chem.Biol., 14, 2007
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