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3RC6

Molecular mechanisms of viral and host-cell substrate recognition by HCV NS3/4A protease

Summary for 3RC6
Entry DOI10.2210/pdb3rc6/pdb
Related3RC4 3RC5
DescriptorNS3/4A, ZINC ION (3 entities in total)
Functional Keywordsdrug resistance, drug design, protease inhibitors, serine protease, viral protein, hydrolase
Biological sourceHepatitis C virus subtype 1a
More
Total number of polymer chains1
Total formula weight21552.74
Authors
Schiffer, C.A.,Romano, K.P. (deposition date: 2011-03-30, release date: 2011-05-04, Last modification date: 2023-09-13)
Primary citationRomano, K.P.,Laine, J.M.,Deveau, L.M.,Cao, H.,Massi, F.,Schiffer, C.A.
Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease.
J.Virol., 85:6106-6116, 2011
Cited by
PubMed: 21507982
DOI: 10.1128/JVI.00377-11
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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