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6ONJ
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Crystal structure of PPARgamma ligand binding domain in complex with TRAP220 peptide and agonist rosiglitazone
分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Mediator of RNA polymerase II transcription subunit 1, ...
著者Shang, J, Kojetin, D.J.
登録日2019-04-22
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A molecular switch regulating transcriptional repression and activation of PPAR gamma.
Nat Commun, 11, 2020
6ONI
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Crystal structure of PPARgamma ligand binding domain in complex with N-CoR peptide and inverse agonist T0070907
分子名称: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, NCOR isoform c, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2019-04-22
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A molecular switch regulating transcriptional repression and activation of PPAR gamma.
Nat Commun, 11, 2020
5HLI
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Structure of Disulfide formed AbfR
分子名称: CHLORIDE ION, COPPER (II) ION, MarR family transcriptional regulator
著者Liu, G, Liu, X, Gan, J, Yang, C.-G.
登録日2016-01-15
公開日2017-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR.
J. Am. Chem. Soc., 139, 2017
5HLG
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Structure of reduced AbfR bound to DNA
分子名称: DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator
著者Liu, G, Liu, X, Gan, J, Yang, C.G.
登録日2016-01-15
公開日2017-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR.
J. Am. Chem. Soc., 139, 2017
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
分子名称: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
4LZL
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Structure of the inactive form of the regulatory domain from the repressor of iron transport regulator (RitR)
分子名称: GLYCEROL, Response regulator
著者Silvaggi, N.R, Han, L, Ulijasz, A.T.
登録日2013-07-31
公開日2014-09-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Defining the Aspartate-Less Receiver (ALR) Domains: Structure and Activation of RitR from Streptococcus pneumoniae
To be Published
4JG3
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BU of 4jg3 by Molmil
Crystal structure of catabolite repression control protein (crc) from Pseudomonas aeruginosa
分子名称: CHLORIDE ION, Catabolite repression control protein
著者Grishkovskaya, I, Milojevic, T, Sonnleitner, E, Blaesi, U, Djinovic-Carugo, K.
登録日2013-02-28
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity
Plos One, 8, 2013
3C2I
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The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF
分子名称: DNA (5'-D(*DAP*DTP*DAP*DGP*DAP*DAP*DGP*DAP*DAP*DTP*DTP*DCP*(5CM)P*DGP*DTP*DTP*DCP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DCP*DTP*DGP*DGP*DAP*DAP*(5CM)P*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DTP*DA)-3'), Methyl-CpG-binding protein 2
著者Ho, K.L, McNae, I.W, Schmiedeberg, L, Klose, R.J, Bird, A.P, Walkinshaw, M.D.
登録日2008-01-25
公開日2008-05-13
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献MeCP2 binding to DNA depends upon hydration at methyl-CpG
Mol.Cell, 29, 2008
6TBT
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BU of 6tbt by Molmil
Crystal structure of the BCL6 BTB domain in complex with an Apt48 peptide
分子名称: Apt48 peptide, B-cell lymphoma 6 protein, CHLORIDE ION, ...
著者Zacharchenko, T, Wright, S.C.
登録日2019-11-04
公開日2021-10-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural basis of Apt48 inhibition of the BCL6 BTB domain.
Structure, 2021
6TCJ
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Crystal structure of the BCL6 BTB domain in complex with a hybrid BTB-binding (HBP) peptide
分子名称: B-cell lymphoma 6 protein, Hybrid BTB-binding (HBP) peptide, SODIUM ION
著者Zacharchenko, T, Wright, S.C.
登録日2019-11-06
公開日2021-10-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural basis of Apt48 inhibition of the BCL6 BTB domain.
Structure, 2021
3ZMU
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BU of 3zmu by Molmil
LSD1-CoREST in complex with PKSFLV peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PKSFLV PEPTIDE, ...
著者Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
登録日2013-02-12
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3ZN0
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BU of 3zn0 by Molmil
LSD1-CoREST in complex with PRSFAA peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
著者Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
登録日2013-02-13
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3ZMT
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BU of 3zmt by Molmil
LSD1-CoREST in complex with PRSFLV peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
著者Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
登録日2013-02-12
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3ZMV
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BU of 3zmv by Molmil
LSD1-CoREST in complex with PLSFLV peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PKSFLV PEPTIDE, ...
著者Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
登録日2013-02-12
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3HTH
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BU of 3hth by Molmil
Crystal structure of multidrug binding protein EbrR complexed with proflavin
分子名称: EbrA repressor, NICKEL (II) ION, PROFLAVIN
著者Dong, J, Ni, L, Schumacher, M, Brennan, R.
登録日2009-06-11
公開日2010-07-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
3ZN1
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BU of 3zn1 by Molmil
LSD1-CoREST in complex with PRLYLV peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
著者Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
登録日2013-02-13
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3HTJ
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BU of 3htj by Molmil
Crystal structure of multidrug binding protein EbrR complexed with ethidium
分子名称: ETHIDIUM, EbrA repressor, NICKEL (II) ION
著者Dong, J, Ni, L, Schumacher, M, Brennan, R.
登録日2009-06-11
公開日2010-07-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
3ZMZ
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BU of 3zmz by Molmil
LSD1-CoREST in complex with PRSFAV peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
著者Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
登録日2013-02-13
公開日2013-06-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
3HTA
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BU of 3hta by Molmil
Crystal structure of multidrug binding protein EbrR complexed with imidazole
分子名称: EbrA repressor, IMIDAZOLE
著者Dong, J, Ni, L, Schumacher, M, Brennan, R.
登録日2009-06-11
公開日2010-07-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
5U4J
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BU of 5u4j by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ...
著者Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
登録日2016-12-04
公開日2017-01-11
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
3PXP
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BU of 3pxp by Molmil
Crystal structure of a PAS and DNA binding domain containing protein (Caur_2278) from CHLOROFLEXUS AURANTIACUS J-10-FL at 2.30 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Helix-turn-helix domain protein, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-12-10
公開日2011-01-19
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes.
Plos One, 7, 2012
5U8K
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RitR mutant - C128S
分子名称: Response regulator
著者Silvaggi, N.R, Han, L.
登録日2016-12-14
公開日2017-12-20
最終更新日2018-11-28
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
6J9B
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BU of 6j9b by Molmil
Arabidopsis FUS3-DNA complex
分子名称: B3 domain-containing transcription factor FUS3, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3')
著者Hu, H, Du, J.
登録日2019-01-22
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
6JQ1
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BU of 6jq1 by Molmil
Crystal Structure of DdrO from Deinococcus geothermalis
分子名称: LITHIUM ION, Transcriptional regulator, XRE family
著者Lu, H, Hua, Y, Zhao, Y.
登録日2019-03-28
公開日2019-08-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO.
Nucleic Acids Res., 47, 2019
5EY0
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BU of 5ey0 by Molmil
Crystal structure of CodY from Staphylococcus aureus with GTP and Ile
分子名称: GTP-sensing transcriptional pleiotropic repressor CodY, GUANOSINE-5'-TRIPHOSPHATE, ISOLEUCINE
著者Han, A, Hwang, K.Y.
登録日2015-11-24
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016

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