7ZX2
 
 | | Tubulin-Pelophen B complex | | 分子名称: | (3R,4S,7S,9S,11S)-3,4,11-trihydroxy-7-((R,Z)-4-(hydroxymethyl)hex-2-en-2-yl)-9-methoxy-12,12-dimethyl-6-oxa-1(1,3)-benzenacyclododecaphan-5-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Estevez-Gallego, J, Diaz, J.F, Van der Eycken, J, Oliva, M.A. | | 登録日 | 2022-05-20 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Structure, 31, 2023
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8A0L
 | | Tubulin-CW1-complex | | 分子名称: | (3~{S},4~{R},8~{S},10~{S},12~{S},14~{S})-14-[(~{Z},4~{R})-4-(hydroxymethyl)hex-2-en-2-yl]-4,12-dimethoxy-9,9-dimethyl-3,8,10-tris(oxidanyl)-1-oxacyclotetradecan-2-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Prota, A.E, Diaz, J.F, Steinmetz, M.O, Oliva, M.A. | | 登録日 | 2022-05-28 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9981 Å) | | 主引用文献 | Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Structure, 31, 2023
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7YWU
 | | Eugenol oxidase from rhodococcus jostii: mutant S81H, A423M, H434Y, S394V, I445D, S518P | | 分子名称: | 2-methoxy-4-(prop-2-en-1-yl)phenol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Alvigini, L, Mattevi, A. | | 登録日 | 2022-02-14 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound.
Nat Commun, 13, 2022
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7YJM
 | | Cryo-EM structure of the monomeric atSPT-ORM1 complex | | 分子名称: | Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORMDL family protein, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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7YJO
 | | Cryo-EM structure of the monomeric atSPT-ORM1 (LCB2a-deltaN5) complex | | 分子名称: | Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORMDL family protein, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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7YJK
 | | Cryo-EM structure of the dimeric atSPT-ORM1 complex | | 分子名称: | Long chain base biosynthesis protein 1, Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-20 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
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7YWV
 | | Eugenol oxidase from rhodococcus jostii: mutant S81H, D151E, A423M, H434Y, S394V, Q425S, I445D, S518P | | 分子名称: | 2-methoxy-4-(prop-2-en-1-yl)phenol, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Alvigini, L, Mattevi, A. | | 登録日 | 2022-02-14 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound.
Nat Commun, 13, 2022
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7ZJV
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8ARJ
 | | Anaplastic Lymphoma Kinase with a novel carboline inhibitor | | 分子名称: | 3-(dimethylamino)-1-[3-[4-(4-methylpiperazin-1-yl)phenyl]-9~{H}-pyrido[2,3-b]indol-6-yl]prop-2-en-1-one, ALK tyrosine kinase receptor | | 著者 | Mologni, L, Scapozza, L, Gambacorti-Passerini, C, Tardy, S, Goekjian, P, Robinson, C, Brown, D. | | 登録日 | 2022-08-17 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.645 Å) | | 主引用文献 | Discovery of Novel alpha-Carboline Inhibitors of the Anaplastic Lymphoma Kinase.
Acs Omega, 7, 2022
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8AP7
 | | membrane region of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APC
 | | rotational state 1c of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APF
 | | rotational state 2a of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APD
 | | rotational state 1d of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APH
 | | rotational state 2c of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APJ
 | | rotational state 2d of Trypanosoma brucei mitochondrial ATP synthase | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APB
 | | rotational state 1b of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APE
 | | rotational state 1e of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APA
 | | rotational state 1a of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APG
 | | rotational state 2b of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8APK
 | | rotational state 3 of the Trypanosoma brucei mitochondrial ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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8AP6
 | | Trypanosoma brucei mitochondrial F1Fo ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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1CF9
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1QF7
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5TZR
 | | GPR40 in complex with partial agonist MK-8666 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, Free fatty acid receptor 1,Endolysin,Free fatty acid receptor 1, ... | | 著者 | Lu, J, Byrne, N, Patel, S, Sharma, S, Soisson, S.M. | | 登録日 | 2016-11-22 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40.
Nat. Struct. Mol. Biol., 24, 2017
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6IIH
 | | crystal structure of mitochondrial calcium uptake 2(MICU2) | | 分子名称: | CALCIUM ION, Endolysin,Calcium uptake protein 2, mitochondrial | | 著者 | Shen, Q, Wu, W, Zheng, J, Jia, Z. | | 登録日 | 2018-10-06 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.958 Å) | | 主引用文献 | The crystal structure of MICU2 provides insight into Ca2+binding and MICU1-MICU2 heterodimer formation.
Embo Rep., 20, 2019
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