3DKJ
| Crystal structure of human NAMPT complexed with benzamide and phosphoribosyl pyrophosphate | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BENZAMIDE, Nicotinamide phosphoribosyltransferase | 著者 | Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L. | 登録日 | 2008-06-25 | 公開日 | 2009-08-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT. Proc.Natl.Acad.Sci.USA, 106, 2009
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2Q88
| Crystal structure of EhuB in complex with ectoine | 分子名称: | (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CADMIUM ION, Putative ABC transporter amino acid-binding protein | 著者 | Hanekop, N, Hoeing, M, Sohn-Bosser, L, Jebbar, M, Schmitt, L, Bremer, E. | 登録日 | 2007-06-09 | 公開日 | 2008-01-01 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the ligand-binding protein EhuB from Sinorhizobium meliloti reveals substrate recognition of the compatible solutes ectoine and hydroxyectoine. J.Mol.Biol., 374, 2007
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2Q8I
| Pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug radicicol | 分子名称: | DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, GLYCEROL, ... | 著者 | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | 登録日 | 2007-06-10 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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3S4R
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2PU2
| AmpC beta-lactamase with bound Phthalamide inhibitor | 分子名称: | 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID, Beta-lactamase, PHOSPHATE ION | 著者 | Babaoglu, K, Shoichet, B.K. | 登録日 | 2007-05-08 | 公開日 | 2008-04-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. J.Med.Chem., 51, 2008
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3S17
| RNA Polymerase II Initiation Complex with a 9-nt RNA | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | 登録日 | 2011-05-14 | 公開日 | 2011-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Initiation complex structure and promoter proofreading. Science, 333, 2011
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3DNX
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3DOO
| Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis complexed with shikimate | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Shikimate dehydrogenase | 著者 | Han, C, Hu, T, Wu, D, Zhou, J, Shen, X, Qu, D, Jiang, H. | 登録日 | 2008-07-05 | 公開日 | 2009-05-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis Febs J., 276, 2009
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2PVK
| Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 | 分子名称: | 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha | 著者 | Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. | 登録日 | 2007-05-09 | 公開日 | 2008-05-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
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3DKH
| L559A mutant of Melanocarpus albomyces laccase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Hakulinen, N, Rouvinen, J. | 登録日 | 2008-06-25 | 公開日 | 2009-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure Febs J., 276, 2009
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3DL9
| Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2 | 分子名称: | (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ... | 著者 | Strushkevich, N.V, Tempel, W, Gilep, A.A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-06-26 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.721 Å) | 主引用文献 | Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2. To be Published
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3SH0
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2PWX
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3DLM
| Crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1 | 分子名称: | Histone-lysine N-methyltransferase SETDB1 | 著者 | Amaya, M.F, Dombrovski, L, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-06-27 | 公開日 | 2008-08-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | The crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1. To be Published
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3SIW
| Crystal structure of NodZ alpha-1,6-fucosyltransferase co-crystallized with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Nodulation fucosyltransferase NodZ, PHOSPHATE ION | 著者 | Brzezinski, K, Dauter, Z, Jaskolski, M. | 登録日 | 2011-06-20 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structures of NodZ alpha-1,6-fucosyltransferase in complex with GDP and GDP-fucose Acta Crystallogr.,Sect.D, 68, 2012
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2PXQ
| Variant 14 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle | 分子名称: | 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein | 著者 | Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S. | 登録日 | 2007-05-14 | 公開日 | 2007-08-07 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure, 15, 2007
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3DRM
| 2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin | 分子名称: | Alpha-1-antitrypsin | 著者 | Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. | 登録日 | 2008-07-11 | 公開日 | 2009-03-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
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2PZF
| Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Atwell, S, Conners, K, Emtage, S, Gheyi, T, Glenn, N.R, Hendle, J, Lewis, H.A, Lu, F, Rodgers, L.A, Romero, R, Sauder, J.M, Smith, D, Tien, H, Wasserman, S.R, Zhao, X. | 登録日 | 2007-05-18 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant. Protein Eng.Des.Sel., 23, 2010
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2PWM
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2PXK
| Variant 8 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle | 分子名称: | 4.5 S RNA, COBALT HEXAMMINE(III), Signal recognition particle protein | 著者 | Keel, A.Y, Rambo, R.P, Batey, R.T, Kieft, J.S. | 登録日 | 2007-05-14 | 公開日 | 2007-08-07 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure, 15, 2007
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3E0S
| Crystal structure of an uncharacterized protein from Chlorobium tepidum | 分子名称: | SULFATE ION, uncharacterized protein | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Powell, A, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-07-31 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of an uncharacterized protein from Chlorobium tepidum To be Published
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2Q0K
| Oxidized thioredoxin reductase from Helicobacter pylori in complex with NADP+ | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase | 著者 | Sandalova, T, Gustafsson, T, Lu, J, Holmgren, A, Schneider, G. | 登録日 | 2007-05-22 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High-resolution structures of oxidized and reduced thioredoxin reductase from Helicobacter pylori. Acta Crystallogr.,Sect.D, 63, 2007
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2PYO
| Drosophila nucleosome core | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | 著者 | Clapier, C.R, Petosa, C, Mueller, C.W. | 登録日 | 2007-05-16 | 公開日 | 2007-11-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins, 71, 2007
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2Q1Y
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3SME
| Structure of PTP1B inactivated by H2O2/bicarbonate | 分子名称: | MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Tanner, J.J, Singh, H. | 登録日 | 2011-06-27 | 公開日 | 2011-10-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Biological Buffer Bicarbonate/CO(2) Potentiates H(2)O(2)-Mediated Inactivation of Protein Tyrosine Phosphatases. J.Am.Chem.Soc., 133, 2011
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