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3E9D
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BU of 3e9d by Molmil
Structure of full-length TIGAR from Danio rerio
分子名称: PHOSPHATE ION, POTASSIUM ION, Zgc:56074
著者Li, H, Jogl, G.
登録日2008-08-21
公開日2008-12-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase
To be Published
3EEJ
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BU of 3eej by Molmil
Candida glabrata Dihydrofolate Reductase complexed with 2,4-diamino-5-[3-methyl-3-(3-methoxy-5-phenylphenyl)prop-1-ynyl]-6-methylpyrimidine(UCP111D) and NADPH
分子名称: 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Liu, J, Anderson, A.
登録日2008-09-04
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors
Chem.Biol.Drug Des., 73, 2009
3EF0
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BU of 3ef0 by Molmil
The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
分子名称: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAFLUOROALUMINATE ION
著者Ghosh, A, Lima, C.D.
登録日2008-09-07
公開日2008-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.
Mol.Cell, 32, 2008
3EA7
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BU of 3ea7 by Molmil
Crystal structure of SARS-CoV main protease triple mutant STI/A in space group P21
分子名称: 3C-like proteinase
著者Shi, J.H, Jayaraman, S, Song, J.X.
登録日2008-08-25
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of SARS-CoV Mpro mutant
To be Published
3DXE
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BU of 3dxe by Molmil
Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2
分子名称: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
著者Radzimanowski, J, Sinning, I, Wild, K.
登録日2008-07-24
公開日2008-09-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
3DXL
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BU of 3dxl by Molmil
Crystal structure of AeD7 from Aedes Aegypti
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Allergen Aed a 2, CHLORIDE ION, ...
著者Andersen, J.F, Calvo, E, Mans, B.J, Ribeiro, J.M.
登録日2008-07-24
公開日2009-02-03
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein
Proc.Natl.Acad.Sci.USA, 106, 2009
3DY9
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BU of 3dy9 by Molmil
Crystal structure of AeD7 potassium bromide soak
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, D7 protein, ...
著者Andersen, J.F, Calvo, E, Mans, B.J, Ribeiro, J.M.
登録日2008-07-25
公開日2009-02-03
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein
Proc.Natl.Acad.Sci.USA, 106, 2009
3DJ4
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BU of 3dj4 by Molmil
Crystal Structure of GlmU from Mycobacterium tuberculosis in complex with URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE.
分子名称: Bifunctional protein glmU, COBALT (II) ION, MAGNESIUM ION, ...
著者Verma, S.K, Prakash, B.
登録日2008-06-22
公開日2009-05-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity.
J.Mol.Biol., 386, 2009
3DZR
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BU of 3dzr by Molmil
Thaumatin by Classical hanging drop method before high X-Ray dose on ESRF ID29 beamline
分子名称: L(+)-TARTARIC ACID, Thaumatin-1
著者Tripathi, S, Pechkova, E, Nicolini, C.
登録日2008-07-30
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective
To be Published
3DKC
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BU of 3dkc by Molmil
Structure of MET receptor tyrosine kinase in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Hepatocyte growth factor receptor, ...
著者Hendle, J.
登録日2008-06-24
公開日2009-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Mol.Cancer Ther., 8, 2009
3DL0
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BU of 3dl0 by Molmil
Crystal structure of adenylate kinase variant AKlse3
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Bannen, R.M, Bianchetti, C.M, Bingman, C.A, McCoy, J.G.
登録日2008-06-26
公開日2009-06-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases.
Proteins, 82, 2014
3E1G
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BU of 3e1g by Molmil
Snapshots of esterase D from lactobacillus rhamnosus: Insights into a rotation driven catalytic mechanism
分子名称: DIETHYL PHOSPHONATE, Esterase D
著者Bennett, M.D, Delabre, M.-L, Holland, R, Norris, G.E.
登録日2008-08-04
公開日2009-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Snapshots of esterase D from lactobacillus rhamnosus: Insights into a rotation driven catalytic mechanism
To be Published
3DGE
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BU of 3dge by Molmil
Structure of a histidine kinase-response regulator complex reveals insights into Two-component signaling and a novel cis-autophosphorylation mechanism
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Response regulator, ...
著者Casino, P, Marina, A.
登録日2008-06-13
公開日2009-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction.
Cell(Cambridge,Mass.), 139, 2009
3DO2
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BU of 3do2 by Molmil
Thermolysin by LB nanotemplate method after high X-Ray dose on ESRF ID14-2 beamline
分子名称: CALCIUM ION, LYSINE, Thermolysin, ...
著者Pechkova, E, Tripathi, S.K, Nicolini, C.
登録日2008-07-03
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective
To be Published
3DOZ
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BU of 3doz by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3k
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DQ0
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BU of 3dq0 by Molmil
Maize cytokinin oxidase/dehydrogenase complexed with N6-(3-methoxy-phenyl)adenine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokinin dehydrogenase 1, ...
著者Kopecny, D, Briozzo, P.
登録日2008-07-09
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Characterization and biological activity of novel purine-derived inhibitor of cytokinin oxidase/dehydrogenase and its potential use for in vivo studies
To be Published
3DQJ
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BU of 3dqj by Molmil
Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 3: Structure 7 in a Series of 26 High Pressure Structures
分子名称: Green fluorescent protein
著者Barstow, B, Kim, C.U.
登録日2008-07-09
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DRU
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BU of 3dru by Molmil
Crystal Structure of Gly117Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DPD
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BU of 3dpd by Molmil
Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-Dihydro-2H-benzo[1,4]oxazines
分子名称: 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者Ceska, T.A.
登録日2008-07-08
公開日2008-08-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines
Bioorg.Med.Chem.Lett., 18, 2008
3DT4
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BU of 3dt4 by Molmil
The structure of rat cytosolic PEPCK in complex with oxalate and GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
著者Sullivan, S.M, Holyoak, T.
登録日2008-07-14
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DUS
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BU of 3dus by Molmil
Crystal structure of SAG506-01, orthorhombic, twinned, crystal 1
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ...
著者Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V.
登録日2008-07-17
公開日2008-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
3DQI
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BU of 3dqi by Molmil
Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 4: Structure 8 in a Series of 26 High Pressure Structures
分子名称: Green fluorescent protein
著者Barstow, B, Kim, C.U.
登録日2008-07-09
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DWS
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BU of 3dws by Molmil
Leishmania major Coproporphyrinogen III Oxidase with bound ligand
分子名称: 5-fluoroindole-2-carboxylic acid, ACETATE ION, Coproporphyrinogen III oxidase
著者Le Trong, I, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2008-07-22
公開日2008-09-09
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Leishmania major Coproporphyrinogen III Oxidase with bound ligand
To be Published
3DQU
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BU of 3dqu by Molmil
Structure of the Yellow Fluorescent Protein Citrine Frozen at 2000 Atmospheres Number 1: Structure 20 in a Series of 26 High Pressure Structures
分子名称: Green fluorescent protein
著者Barstow, B, Kim, C.U.
登録日2008-07-09
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DX3
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BU of 3dx3 by Molmil
Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetraol
分子名称: (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetrol, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kuntz, D.A, Rose, D.R.
登録日2008-07-23
公開日2009-07-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A.
Chembiochem, 10, 2009

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