8GUK
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![BU of 8guk by Molmil](/molmil-images/mine/8guk) | Human nucleosome core particle (free form) | 分子名称: | DNA (147-mer), Histone H2A type 1, Histone H2B type 1-J, ... | 著者 | Onishi, S, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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2ORH
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2ORF
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![BU of 2orf by Molmil](/molmil-images/mine/2orf) | |
8J12
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![BU of 8j12 by Molmil](/molmil-images/mine/8j12) | Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (247-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-12 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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4GNX
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8VFX
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7CRP
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![BU of 7crp by Molmil](/molmil-images/mine/7crp) | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode) | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | 登録日 | 2020-08-14 | 公開日 | 2020-10-21 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
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8VG0
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5WE0
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![BU of 5we0 by Molmil](/molmil-images/mine/5we0) | Structural Basis for Shelterin Bridge Assembly | 分子名称: | DNA-binding protein rap1, Protection of telomeres protein poz1, Protection of telomeres protein tpz1, ... | 著者 | Kim, J.-K, Liu, J, Hu, X, Yu, C, Roskamp, K, Sankaran, B, Huang, L, Komives, E.-A, Qiao, F. | 登録日 | 2017-07-06 | 公開日 | 2017-12-20 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for Shelterin Bridge Assembly. Mol. Cell, 68, 2017
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5X0X
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![BU of 5x0x by Molmil](/molmil-images/mine/5x0x) | Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome | 分子名称: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | 登録日 | 2017-01-23 | 公開日 | 2017-04-19 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure. Nature, 544, 2017
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5X0Y
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![BU of 5x0y by Molmil](/molmil-images/mine/5x0y) | Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome | 分子名称: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | 登録日 | 2017-01-23 | 公開日 | 2017-04-19 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.69 Å) | 主引用文献 | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure. Nature, 544, 2017
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6JQS
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![BU of 6jqs by Molmil](/molmil-images/mine/6jqs) | Structure of Transcription factor, GerE | 分子名称: | DNA-binding response regulator | 著者 | Lee, J.H, Lee, C.W. | 登録日 | 2019-04-01 | 公開日 | 2019-04-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of a transcription factor, GerE (PaGerE), from spore-forming bacterium Paenisporosarcina sp. TG-14. Biochem.Biophys.Res.Commun., 513, 2019
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6KIW
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![BU of 6kiw by Molmil](/molmil-images/mine/6kiw) | Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) | 分子名称: | DNA (144-MER), DNA (145-MER), Histone H2A, ... | 著者 | Huang, J, Xue, H, Yao, T. | 登録日 | 2019-07-20 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
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2ORG
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![BU of 2org by Molmil](/molmil-images/mine/2org) | |
1VTO
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2LOX
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2DWN
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![BU of 2dwn by Molmil](/molmil-images/mine/2dwn) | Crystal structure of the PriA protein complexed with oligonucleotides | 分子名称: | DNA (5'-D(*A*G)-3'), Primosomal protein N' | 著者 | Sasaki, K, Ose, T, Tanaka, T, Masai, H, Maenaka, K, Kohda, D. | 登録日 | 2006-08-15 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA. EMBO J., 26, 2007
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6VBH
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![BU of 6vbh by Molmil](/molmil-images/mine/6vbh) | Human XPG endonuclease catalytic domain | 分子名称: | DNA repair protein complementing XP-G cells,Flap endonuclease 1, SULFATE ION | 著者 | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | 登録日 | 2019-12-18 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | 主引用文献 | Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proc.Natl.Acad.Sci.USA, 117, 2020
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8EIH
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8EII
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8EIK
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![BU of 8eik by Molmil](/molmil-images/mine/8eik) | Cryo-EM structure of human DNMT3B homo-hexamer | 分子名称: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Lu, J.W, Song, J.K. | 登録日 | 2022-09-15 | 公開日 | 2023-09-20 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51, 2023
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8EIJ
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![BU of 8eij by Molmil](/molmil-images/mine/8eij) | Cryo-EM structure of human DNMT3B homo-trimer | 分子名称: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Lu, J.W, Song, J.K. | 登録日 | 2022-09-15 | 公開日 | 2023-09-20 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51, 2023
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1EN1
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![BU of 1en1 by Molmil](/molmil-images/mine/1en1) | STRUCTURE OF THE HIV-1 MINUS STRAND PRIMER BINDING SITE | 分子名称: | DNA (5'-D(P*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3') | 著者 | Johnson, P.E, Turner, R.B, Wu, Z.R, Levin, J.G, Summers, M.F. | 登録日 | 2000-03-20 | 公開日 | 2000-04-04 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A mechanism for plus-strand transfer enhancement by the HIV-1 nucleocapsid protein during reverse transcription Biochemistry, 39, 2000
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2MBJ
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![BU of 2mbj by Molmil](/molmil-images/mine/2mbj) | Structure of an antiparallel (2+2) G-quadruplex formed by human telomeric repeats in Na+ solution (with G22-to-BrG substitution) | 分子名称: | DNA_(27-MER) | 著者 | Lim, K.W, Ng, V.C.M, Martin-Pintado, N, Heddi, B, Phan, A.T. | 登録日 | 2013-08-02 | 公開日 | 2013-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity. Nucleic Acids Res., 41, 2013
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1DNX
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![BU of 1dnx by Molmil](/molmil-images/mine/1dnx) | RNA/DNA DODECAMER R(G)D(CGTATACGC) WITH MAGNESIUM BINDING SITES | 分子名称: | DNA/RNA (5'-R(*GP)-D(*CP*GP*TP*AP*TP*AP*CP*GP*C)-3'), MAGNESIUM ION | 著者 | Robinson, H, Gao, Y.-G, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | 登録日 | 1999-12-16 | 公開日 | 2000-04-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes. Nucleic Acids Res., 28, 2000
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