1U5B
| Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase | 分子名称: | 2-oxoisovalerate dehydrogenase alpha subunit, 2-oxoisovalerate dehydrogenase beta subunit, GLYCEROL, ... | 著者 | Wynn, R.M, Kato, M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | 登録日 | 2004-07-27 | 公開日 | 2004-11-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation Structure, 12, 2004
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7B1G
| TRPC4 in complex with Calmodulin | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-24 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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8BXG
| Structure of the K/H exchanger KefC. | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE MONOPHOSPHATE, Glutathione-regulated potassium-efflux system protein KefC, ... | 著者 | Gulati, A, Drew, D. | 登録日 | 2022-12-08 | 公開日 | 2023-12-20 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structure and mechanism of the K + /H + exchanger KefC. Nat Commun, 15, 2024
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8BY2
| Structure of the K+/H+ exchanger KefC with GSH. | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE MONOPHOSPHATE, GLUTATHIONE, ... | 著者 | Gulati, A, Drew, D. | 登録日 | 2022-12-11 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structure and mechanism of the K + /H + exchanger KefC. Nat Commun, 15, 2024
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1Y62
| A 2.4 crystal structure of conkunitzin-S1, a novel Kunitz-fold cone snail neurotoxin. | 分子名称: | Conkunitzin-S1, SULFATE ION | 著者 | Dy, C.Y, Buczek, P, Horvath, M.P. | 登録日 | 2004-12-03 | 公開日 | 2005-07-12 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snail. Acta Crystallogr.,Sect.D, 62, 2006
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6WZB
| Crystal structure of the GltPh V216C-G388C mutant cross-linked with divalent mercury | 分子名称: | ASPARTIC ACID, Glutamate transporter homolog, MERCURY (II) ION, ... | 著者 | Chen, I, Font, J, Ryan, R. | 登録日 | 2020-05-13 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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5A15
| Crystal structure of the BTB domain of human KCTD16 | 分子名称: | BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD16 | 著者 | Pinkas, D.M, Sanvitale, C.E, Solcan, N, Goubin, S, Canning, P, Dixon Clarke, S.E, Talon, R, Wiggers, H.J, Fitzpatrick, F, Tallant, C, Kopec, J, Chalk, R, Doutch, J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2015-04-28 | 公開日 | 2015-11-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases. Biochem. J., 474, 2017
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5FTA
| Crystal structure of the N-terminal BTB domain of human KCTD10 | 分子名称: | BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3, MERCURY (II) ION | 著者 | Pinkas, D.M, Sanvitale, C.E, Solcan, N, Goubin, S, Tallant, C, Newman, J.A, Kopec, J, Fitzpatrick, F, Talon, R, Collins, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2016-01-12 | 公開日 | 2016-02-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases. Biochem. J., 474, 2017
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4XGC
| Crystal structure of the eukaryotic origin recognition complex | 分子名称: | CHLORIDE ION, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | 著者 | Bleichert, F, Botchan, M.R, Berger, J.M. | 登録日 | 2014-12-30 | 公開日 | 2015-04-01 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the eukaryotic origin recognition complex. Nature, 519, 2015
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4TNW
| C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, ... | 著者 | Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E. | 登録日 | 2014-06-05 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors. Nature, 512, 2014
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4TNV
| C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, CHLORIDE ION, ... | 著者 | Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E. | 登録日 | 2014-06-05 | 公開日 | 2014-08-13 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors. Nature, 512, 2014
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5BUT
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7TJ5
| SthK closed state, cAMP-bound in the presence of POPA | 分子名称: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | 著者 | Schmidpeter, P.A, Nimigean, C.M. | 登録日 | 2022-01-14 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nat.Struct.Mol.Biol., 29, 2022
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7TKT
| SthK closed state, cAMP-bound in the presence of detergent | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | 著者 | Rheinberger, J, Schmidpeter, P.A, Nimigean, C.M. | 登録日 | 2022-01-17 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nat.Struct.Mol.Biol., 29, 2022
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7TJ6
| SthK open state, cAMP-bound in the presence of POPA | 分子名称: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | 著者 | Schmidpeter, P.A, Nimigean, C.M. | 登録日 | 2022-01-14 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nat.Struct.Mol.Biol., 29, 2022
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1NPI
| Tityus Serrulatus Neurotoxin (Ts1) at atomic resolution | 分子名称: | PHOSPHATE ION, Toxin VII | 著者 | Pinheiro, C.B, Marangoni, S, Toyama, M.H, Polikarpov, I. | 登録日 | 2003-01-17 | 公開日 | 2003-02-25 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels. Acta Crystallogr.,Sect.D, 59, 2003
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8VIC
| AP-6 bound human TMEM175 | 分子名称: | (2P,2'P)-2,2'-(1,3-phenylene)di(pyridin-4-amine), Endosomal/lysosomal potassium channel TMEM175 | 著者 | Oh, S, Hite, R.K. | 登録日 | 2024-01-03 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structure of human TMEM175 in an inhibitor-bound state To Be Published
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7RK6
| Aplysia Slo1 with Barium | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ... | 著者 | Zhu, J, Srivastava, S, Cachau, R, Holmgren, M. | 登録日 | 2021-07-22 | 公開日 | 2022-06-22 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A To Be Published
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7RJT
| Aplysia Slo1 with Barium | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ... | 著者 | Zhu, J, Srivastava, S, Cachau, R, Holmgren, M. | 登録日 | 2021-07-21 | 公開日 | 2022-06-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A To Be Published
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8OFI
| Ivabradine bound to HCN4 channel | 分子名称: | Ivabradine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Saponaro, A, Chaves-Sanjuan, A, Sharifzadeh, A.S, Clarke, O.B, Marabelli, C, Bolognesi, M, Thiel, G, Moroni, A. | 登録日 | 2023-03-15 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural determinants of ivabradine block of the open pore of HCN4. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VIE
| 2-PPA bound human TMEM175 | 分子名称: | 2-phenylpyridin-4-amine, Endosomal/lysosomal potassium channel TMEM175 | 著者 | Oh, S, Hite, R.K. | 登録日 | 2024-01-04 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structure of human TMEM175 in an inhibitor-bound state To Be Published
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1W5U
| GRAMICIDIN D FROM BACILLUS BREVIS (ETHANOL SOLVATE) | 分子名称: | CHLORIDE ION, ETHANOL, GRAMICIDIN D, ... | 著者 | Glowka, M.L, Olczak, A, Bojarska, J, Szczesio, M, Duax, W.L, Burkhart, B.M, Pangborn, W.A, Langs, D.A, Wawrzak, Z. | 登録日 | 2004-08-10 | 公開日 | 2005-09-15 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Structure of Gramicidin D-Rbcl Complex at Atomic Resolution from Low-Temperature Synchrotron Data: Interactions of Double-Stranded Gramicidin Channel Contents and Cations with Channel Wall Acta Crystallogr.,Sect.D, 61, 2005
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6A5I
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1NE5
| Solution Structure of HERG Specific Scorpion Toxin CnErg1 | 分子名称: | ergtoxin | 著者 | Torres, A.M, Paramjit, B, Alewood, P, Kuchel, P.W, Vandenberg, J.I. | 登録日 | 2002-12-10 | 公開日 | 2003-04-01 | 最終更新日 | 2024-11-06 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin FEBS Lett., 539, 2003
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6R88
| Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with glycine | 分子名称: | CHLORIDE ION, GLYCEROL, GLYCINE, ... | 著者 | Alfieri, A, Pederzoli, R, Costa, A. | 登録日 | 2019-04-01 | 公開日 | 2020-01-01 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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