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1U5B
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Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase
分子名称: 2-oxoisovalerate dehydrogenase alpha subunit, 2-oxoisovalerate dehydrogenase beta subunit, GLYCEROL, ...
著者Wynn, R.M, Kato, M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T.
登録日2004-07-27
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation
Structure, 12, 2004
7B1G
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TRPC4 in complex with Calmodulin
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ...
著者Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S.
登録日2020-11-24
公開日2020-12-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
8BXG
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Structure of the K/H exchanger KefC.
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE MONOPHOSPHATE, Glutathione-regulated potassium-efflux system protein KefC, ...
著者Gulati, A, Drew, D.
登録日2022-12-08
公開日2023-12-20
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure and mechanism of the K + /H + exchanger KefC.
Nat Commun, 15, 2024
8BY2
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Structure of the K+/H+ exchanger KefC with GSH.
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE MONOPHOSPHATE, GLUTATHIONE, ...
著者Gulati, A, Drew, D.
登録日2022-12-11
公開日2023-12-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structure and mechanism of the K + /H + exchanger KefC.
Nat Commun, 15, 2024
1Y62
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A 2.4 crystal structure of conkunitzin-S1, a novel Kunitz-fold cone snail neurotoxin.
分子名称: Conkunitzin-S1, SULFATE ION
著者Dy, C.Y, Buczek, P, Horvath, M.P.
登録日2004-12-03
公開日2005-07-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snail.
Acta Crystallogr.,Sect.D, 62, 2006
6WZB
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BU of 6wzb by Molmil
Crystal structure of the GltPh V216C-G388C mutant cross-linked with divalent mercury
分子名称: ASPARTIC ACID, Glutamate transporter homolog, MERCURY (II) ION, ...
著者Chen, I, Font, J, Ryan, R.
登録日2020-05-13
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Glutamate transporters have a chloride channel with two hydrophobic gates.
Nature, 591, 2021
5A15
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Crystal structure of the BTB domain of human KCTD16
分子名称: BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD16
著者Pinkas, D.M, Sanvitale, C.E, Solcan, N, Goubin, S, Canning, P, Dixon Clarke, S.E, Talon, R, Wiggers, H.J, Fitzpatrick, F, Tallant, C, Kopec, J, Chalk, R, Doutch, J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2015-04-28
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem. J., 474, 2017
5FTA
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Crystal structure of the N-terminal BTB domain of human KCTD10
分子名称: BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3, MERCURY (II) ION
著者Pinkas, D.M, Sanvitale, C.E, Solcan, N, Goubin, S, Tallant, C, Newman, J.A, Kopec, J, Fitzpatrick, F, Talon, R, Collins, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2016-01-12
公開日2016-02-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem. J., 474, 2017
4XGC
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BU of 4xgc by Molmil
Crystal structure of the eukaryotic origin recognition complex
分子名称: CHLORIDE ION, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Bleichert, F, Botchan, M.R, Berger, J.M.
登録日2014-12-30
公開日2015-04-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the eukaryotic origin recognition complex.
Nature, 519, 2015
4TNW
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C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, ...
著者Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E.
登録日2014-06-05
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
4TNV
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C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, CHLORIDE ION, ...
著者Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E.
登録日2014-06-05
公開日2014-08-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
5BUT
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BU of 5but by Molmil
Crystal structure of inactive conformation of KtrAB K+ transporter
分子名称: Ktr system potassium uptake protein A,Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, POTASSIUM ION
著者Vieira-Pires, R.S, Morais-Cabral, J.H.
登録日2015-06-04
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (5.97 Å)
主引用文献Dissecting the Molecular Mechanism of Nucleotide-Dependent Activation of the KtrAB K+ Transporter.
Plos Biol., 14, 2016
7TJ5
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BU of 7tj5 by Molmil
SthK closed state, cAMP-bound in the presence of POPA
分子名称: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
著者Schmidpeter, P.A, Nimigean, C.M.
登録日2022-01-14
公開日2022-10-26
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7TKT
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SthK closed state, cAMP-bound in the presence of detergent
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
著者Rheinberger, J, Schmidpeter, P.A, Nimigean, C.M.
登録日2022-01-17
公開日2022-10-26
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7TJ6
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SthK open state, cAMP-bound in the presence of POPA
分子名称: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
著者Schmidpeter, P.A, Nimigean, C.M.
登録日2022-01-14
公開日2022-10-26
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
1NPI
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BU of 1npi by Molmil
Tityus Serrulatus Neurotoxin (Ts1) at atomic resolution
分子名称: PHOSPHATE ION, Toxin VII
著者Pinheiro, C.B, Marangoni, S, Toyama, M.H, Polikarpov, I.
登録日2003-01-17
公開日2003-02-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels.
Acta Crystallogr.,Sect.D, 59, 2003
8VIC
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BU of 8vic by Molmil
AP-6 bound human TMEM175
分子名称: (2P,2'P)-2,2'-(1,3-phenylene)di(pyridin-4-amine), Endosomal/lysosomal potassium channel TMEM175
著者Oh, S, Hite, R.K.
登録日2024-01-03
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structure of human TMEM175 in an inhibitor-bound state
To Be Published
7RK6
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Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-22
公開日2022-06-22
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A
To Be Published
7RJT
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Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-21
公開日2022-06-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A
To Be Published
8OFI
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BU of 8ofi by Molmil
Ivabradine bound to HCN4 channel
分子名称: Ivabradine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Saponaro, A, Chaves-Sanjuan, A, Sharifzadeh, A.S, Clarke, O.B, Marabelli, C, Bolognesi, M, Thiel, G, Moroni, A.
登録日2023-03-15
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural determinants of ivabradine block of the open pore of HCN4.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VIE
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2-PPA bound human TMEM175
分子名称: 2-phenylpyridin-4-amine, Endosomal/lysosomal potassium channel TMEM175
著者Oh, S, Hite, R.K.
登録日2024-01-04
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structure of human TMEM175 in an inhibitor-bound state
To Be Published
1W5U
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GRAMICIDIN D FROM BACILLUS BREVIS (ETHANOL SOLVATE)
分子名称: CHLORIDE ION, ETHANOL, GRAMICIDIN D, ...
著者Glowka, M.L, Olczak, A, Bojarska, J, Szczesio, M, Duax, W.L, Burkhart, B.M, Pangborn, W.A, Langs, D.A, Wawrzak, Z.
登録日2004-08-10
公開日2005-09-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Structure of Gramicidin D-Rbcl Complex at Atomic Resolution from Low-Temperature Synchrotron Data: Interactions of Double-Stranded Gramicidin Channel Contents and Cations with Channel Wall
Acta Crystallogr.,Sect.D, 61, 2005
6A5I
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Pseudocerastes Persicus Trypsin Inhibitor
分子名称: Trypsin Inhibitor
著者Amininasab, M.
登録日2018-06-23
公開日2019-05-01
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Structural characterization of PPTI, a kunitz-type protein from the venom of Pseudocerastes persicus.
PLoS ONE, 14, 2019
1NE5
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BU of 1ne5 by Molmil
Solution Structure of HERG Specific Scorpion Toxin CnErg1
分子名称: ergtoxin
著者Torres, A.M, Paramjit, B, Alewood, P, Kuchel, P.W, Vandenberg, J.I.
登録日2002-12-10
公開日2003-04-01
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin
FEBS Lett., 539, 2003
6R88
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Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with glycine
分子名称: CHLORIDE ION, GLYCEROL, GLYCINE, ...
著者Alfieri, A, Pederzoli, R, Costa, A.
登録日2019-04-01
公開日2020-01-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel.
Proc.Natl.Acad.Sci.USA, 117, 2020

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件を2024-11-06に公開中

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