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7TJ6

SthK open state, cAMP-bound in the presence of POPA

Summary for 7TJ6
Entry DOI10.2210/pdb7tj6/pdb
EMDB information25916 25917 25981
DescriptorPutative transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate (3 entities in total)
Functional Keywordscyclic nucleotide-gated channel, lipid modulation, pacemaker channel, transport protein
Biological sourceSpirochaeta thermophila DSM 6578
Total number of polymer chains4
Total formula weight221989.42
Authors
Schmidpeter, P.A.,Nimigean, C.M. (deposition date: 2022-01-14, release date: 2022-10-26, Last modification date: 2024-06-05)
Primary citationSchmidpeter, P.A.M.,Wu, D.,Rheinberger, J.,Riegelhaupt, P.M.,Tang, H.,Robinson, C.V.,Nimigean, C.M.
Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29:1092-1100, 2022
Cited by
PubMed: 36352139
DOI: 10.1038/s41594-022-00851-2
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.9 Å)
Structure validation

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