PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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2R0V	Structure of the Rsc4 tandem bromodomain acetylated at K25 分子名称: Chromatin structure-remodeling complex protein RSC4, SULFATE ION 著者 VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. 登録日 2007-08-21 公開日 2007-10-30 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol.Cell, 27, 2007
3QEU	The crystal structure of TCR DMF5 分子名称: DMF5 alpha chain, DMF5 beta chain, GLYCEROL, ... 著者 Borbulevych, O.Y, Santhanagopolan, S.M, Baker, B.M. 登録日 2011-01-20 公開日 2011-07-06 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms. J.Immunol., 187, 2011
3HHP	Malate dehydrogenase open conformation 分子名称: Malate dehydrogenase 著者 Zaitseva, J, Meneely, K.M, Lamb, A.L. 登録日 2009-05-15 公開日 2009-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution. Acta Crystallogr.,Sect.F, 65, 2009
4KY8	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, methotrexate, FdUMP and 4-((2-amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)thio)-2-chlorophenyl)-L-glutamic acid 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional thymidylate synthase-dihydrofolate reductase, METHOTREXATE, ... 著者 Kumar, V.P, Anderson, K.S. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.084 Å) 主引用文献 Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
2QDP	Crystal structure of the HePTP catalytic domain C270S mutant crystallized in ammonium acetate 分子名称: PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 7 著者 Critton, D.A, Tortajada, A, Page, R. 登録日 2007-06-21 公開日 2008-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural basis of substrate recognition by hematopoietic tyrosine phosphatase. To be published
4KXV	Human transketolase in covalent complex with donor ketose D-xylulose-5-phosphate, crystal 1 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, D-XYLITOL-5-PHOSPHATE, ... 著者 Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. 登録日 2013-05-28 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate. Nat Chem, 5, 2013
4P98	ABC transporter system solute-bindng protein from Conexibacter woesei DSM 14684 分子名称: BROMIDE ION, Extracellular solute-binding protein 著者 Chang, C, Endres, M, Joachimiak, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2014-04-02 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 ABC transporter system solute-bindng protein from Conexibacter woesei DSM 14684 To Be Published
2FD4	Crystal Structure of AvrPtoB (436-553) 分子名称: avirulence protein AvrptoB 著者 Janjusevic, R, Stebbins, C.E. 登録日 2005-12-13 公開日 2005-12-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase. Science, 311, 2006
4KZ5	Crystal structure of AmpC beta-lactamase in complex with fragment 5 (N-{[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}glycine) 分子名称: Beta-lactamase, N-{[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}glycine, PHOSPHATE ION 著者 Eidam, O, Barelier, S, Fish, I, Shoichet, B.K. 登録日 2013-05-29 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Increasing chemical space coverage by combining empirical and computational fragment screens. Acs Chem.Biol., 9, 2014
3HF7	The Crystal Structure of a CBS-domain Pair with Bound AMP from Klebsiella pneumoniae to 2.75A 分子名称: ADENOSINE MONOPHOSPHATE, uncharacterized CBS-domain protein 著者 Stein, A.J, Nocek, B, Wu, R, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-05-11 公開日 2009-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The Crystal Structure of a CBS-domain Pair with Bound AMP from Klebsiella pneumoniae to 2.75A To be Published
4KZJ	Crystal Structure of TR3 LBD L449W Mutant 分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Li, F, Zhang, Q, Li, A, Tian, X, Cai, Q, Wang, W, Wang, Y, Chen, H, Xing, Y, Wu, Q, Lin, T. 登録日 2013-05-30 公開日 2013-12-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat.Chem.Biol., 10, 2014
2R4J	Crystal structure of Escherichia coli SeMet substituted Glycerol-3-phosphate Dehydrogenase in complex with DHAP 分子名称: 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, Aerobic glycerol-3-phosphate dehydrogenase, ... 著者 Yeh, J.I, Du, S, Chinte, U. 登録日 2007-08-31 公開日 2008-06-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism. Proc.Natl.Acad.Sci.Usa, 105, 2008
3HFG	Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Sulfonyl-piperazine Inhibitor 分子名称: (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Bard, J, Svenson, K. 登録日 2009-05-11 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J.Med.Chem., 52, 2009
4L45	Crystal structures of human p70S6K1-T389E 分子名称: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein 著者 Wang, J, Zhong, C, Ding, J. 登録日 2013-06-07 公開日 2013-07-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
2QIO	X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis with Triclosan 分子名称: Enoyl-(Acyl-carrier-protein) reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN 著者 Klein, G.M, Santarsiero, B.D, Mesecar, A.D. 登録日 2007-07-05 公開日 2008-07-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase. Chemmedchem, 3, 2008
3HKK	Structure of human Leukotriene C4 synthase in complex with glutathione sulfonate 分子名称: GLUTATHIONE SULFONIC ACID, Leukotriene C4 synthase, PALMITIC ACID, ... 著者 Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2009-05-24 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Pre-steady state kinetics of human Leukotriene C4 synthase To be Published
3HIS	Crystal structure of Saporin-L1 from Saponaria officinalis 分子名称: Vacuolar saporin 著者 Ho, M, Sturm, M.B, Almo, S.C, Schramm, V.L. 登録日 2009-05-20 公開日 2009-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins. Proc.Natl.Acad.Sci.USA, 106, 2009
3HJ5	Human prion protein variant V129 domain swapped dimer 分子名称: Major prion protein 著者 Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. 登録日 2009-05-20 公開日 2010-01-12 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. Embo J., 29, 2010
3HII	Crystal structure of human diamine oxidase in complex with the inhibitor pentamidine 分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive amine oxidase, ... 著者 McGrath, A.P, Guss, J.M. 登録日 2009-05-20 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Structure and inhibition of human diamine oxidase Biochemistry, 48, 2009
2QIH	Crystal structure of 527-665 fragment of UspA1 protein from Moraxella catarrhalis 分子名称: CHLORIDE ION, PHOSPHATE ION, protein UspA1 著者 Conners, R, Brady, R.L. 登録日 2007-07-04 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.897 Å) 主引用文献 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. Embo J., 27, 2008
3HQY	Discovery of novel inhibitors of PDE10A 分子名称: 2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline, MAGNESIUM ION, SULFATE ION, ... 著者 Pandit, J, Marr, E.S. 登録日 2009-06-08 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia J.Med.Chem., 52, 2009
3HR8	Crystal Structure of Thermotoga maritima RecA 分子名称: Protein recA 著者 Lee, S, Kim, T.G, Jeong, E.-Y, Ban, C, Jeon, W.-J, Min, K.I, Song, K.-M, Heo, S.-D, Ku, J.K. 登録日 2009-06-09 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of RecA Protein from Thermotoga maritima MSB8 to be published
2QON	Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742A triple mutant 分子名称: Ephrin receptor, GLYCEROL 著者 Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2007-07-20 公開日 2007-08-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16, 2008
2QK0	Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1 分子名称: CAP-Gly domain-containing linker protein 1 著者 Slep, K.C, Vale, R.D. 登録日 2007-07-09 公開日 2007-10-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1. Mol.Cell, 27, 2007
4LB3	Crystal structure of human AR complexed with NADP+ and {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid 著者 Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. 登録日 2013-06-20 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.8 Å) 主引用文献 Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013

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