4WIA
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8HQG
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4WIM
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8HRZ
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8HQ7
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4WJ7
| CCM2 PTB domain in complex with KRIT1 NPxY/F3 | 分子名称: | KRIT1 NPxY/F3, Malcavernin | 著者 | Fisher, O.S, Liu, W, Zhang, R, Stiegler, A.L, Boggon, T.J. | 登録日 | 2014-09-29 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.753 Å) | 主引用文献 | Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations. J.Biol.Chem., 290, 2015
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8HQI
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4WJK
| Metal Ion and Ligand Binding of Integrin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Xia, W, Springer, T.A. | 登録日 | 2014-09-30 | 公開日 | 2014-12-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Metal ion and ligand binding of integrin alpha 5 beta 1. Proc.Natl.Acad.Sci.USA, 111, 2014
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4WH3
| N-acetylhexosamine 1-kinase in complex with ATP | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | 著者 | Sato, M, Arakawa, T, Nam, Y.W, Nishimoto, M, Kitaoka, M, Fushinobu, S. | 登録日 | 2014-09-19 | 公開日 | 2015-02-18 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase Biochim.Biophys.Acta, 1854, 2015
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8HNA
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4WH8
| Crystal Structure of HCV NS3/4A protease in complex with an Asunaprevir P1-P3 macrocyclic analog. | 分子名称: | Genome polyprotein, SULFATE ION, ZINC ION, ... | 著者 | Soumana, D.I, Ali, A, Schiffer, C.A. | 登録日 | 2014-09-20 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Structural Analysis of Asunaprevir Resistance in HCV NS3/4A Protease. Acs Chem.Biol., 9, 2014
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8HQH
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8HRM
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4WHH
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8HQW
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4WHN
| Structure of toxin-activating acyltransferase (TAAT) | 分子名称: | ApxC, CITRIC ACID | 著者 | Crow, A, Greene, N.P, Hughes, C, Koronakis, V. | 登録日 | 2014-09-23 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of a bacterial toxin-activating acyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
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8HR4
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4WK1
| Crystal structure of Staphylococcus aureus PstA in complex with c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, PstA | 著者 | Mueller, M, Hopfner, K.-P, Witte, G. | 登録日 | 2014-10-01 | 公開日 | 2014-11-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | c-di-AMP recognition by Staphylococcus aureus PstA. Febs Lett., 589, 2015
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4WK3
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8HRF
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4WK7
| Crystal structure of human ADAMTS-4 in complex with inhibitor (compound 1, 2-(4-chlorophenoxy)-N-{[(4R)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl} acetamide) | 分子名称: | 2-(4-chlorophenoxy)-N-{[(4R)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl}acetamide, A disintegrin and metalloproteinase with thrombospondin motifs 4, CALCIUM ION, ... | 著者 | Durbin, J.D, Stout, S.L. | 登録日 | 2014-10-01 | 公開日 | 2014-12-10 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis. J.Med.Chem., 57, 2014
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8HPB
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4WKC
| Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin-A | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, TETRAETHYLENE GLYCOL | 著者 | Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L. | 登録日 | 2014-10-02 | 公開日 | 2015-08-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Active site and remote contributions to catalysis in methylthioadenosine nucleosidases. Biochemistry, 54, 2015
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8HRK
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4WHU
| BROMO domain of CREB binding protein | 分子名称: | 2-methoxy-4-{1-[2-(morpholin-4-yl)ethyl]-2-(2-phenylethyl)-1H-benzimidazol-5-yl}cyclohepta-2,4,6-trien-1-one, CREB-binding protein | 著者 | Liu, S. | 登録日 | 2014-09-23 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Direct photocapture of bromodomains using tropolone chemical probes To Be Published
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