8HQG

Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with inhibitor YH-53

Summary for 8HQG

• Entry DOI: 10.2210/pdb8hqg/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, k90r mutant, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 67505.05

Authors

Wang, J.,Zhang, J.,Li, J. (deposition date: 2022-12-13, release date: 2023-12-20)

• Primary citation: Wang, J.,Zhang, J.,Li, J.; Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with inhibitor YH-53; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.88 Å)