1YMU
 
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1J7Z
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1YMV
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1J81
 | | Osmolyte Stabilization of RNase | | 分子名称: | RIBONUCLEASE PANCREATIC, SULFATE ION | | 著者 | Ratnaparkhi, G.S, Varadarajan, R. | | 登録日 | 2001-05-19 | | 公開日 | 2001-06-06 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states.
J.Biol.Chem., 276, 2001
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1YTJ
 | | SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT | | 分子名称: | PEPTIDE PRODUCT, SIV PROTEASE | | 著者 | Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M. | | 登録日 | 1996-08-01 | | 公開日 | 1997-03-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
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1YJA
 | | SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 20% DIMETHYLFORMAMIDE | | 分子名称: | CALCIUM ION, SUBTILISIN 8397+1 | | 著者 | Kidd, R.D, Farber, G.K. | | 登録日 | 1996-01-16 | | 公開日 | 1996-07-11 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Breaking the low barrier hydrogen bond in a serine protease.
Protein Sci., 8, 1999
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1YJC
 | | SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 50% DIMETHYLFORMAMIDE | | 分子名称: | CALCIUM ION, SUBTILISIN 8397+1 | | 著者 | Kidd, R.D, Farber, G.K. | | 登録日 | 1996-01-16 | | 公開日 | 1996-07-11 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Breaking the low barrier hydrogen bond in a serine protease.
Protein Sci., 8, 1999
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1YIC
 | | THE OXIDIZED SACCHAROMYCES CEREVISIAE ISO-1-CYTOCHROME C, NMR, 20 STRUCTURES | | 分子名称: | CYTOCHROME C, ISO-1, HEME C | | 著者 | Banci, L, Bertini, I, Bren, K.L, Gray, H.B, Sompornpisut, P, Turano, P. | | 登録日 | 1997-02-18 | | 公開日 | 1997-07-23 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of oxidized Saccharomyces cerevisiae iso-1-cytochrome c.
Biochemistry, 36, 1997
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1YTH
 | | SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT | | 分子名称: | HIV PROTEASE, PEPTIDE PRODUCT | | 著者 | Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M. | | 登録日 | 1996-08-01 | | 公開日 | 1997-03-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
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2A51
 | | Structure of the (13-51) domain of the nucleocapsid protein NCp8 from SIVlhoest | | 分子名称: | ZINC ION, nucleocapsid protein | | 著者 | Morellet, N, Meudal, H, Bouaziz, S, Roques, B.P. | | 登録日 | 2005-06-30 | | 公開日 | 2006-06-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the zinc finger domain encompassing residues 13-51 of the nucleocapsid protein from simian immunodeficiency virus
Biochem.J., 393, 2006
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1INY
 | | A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES | | 分子名称: | (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | White, C.L, Janakiraman, M.N, Laver, W.G, Philippon, C, Vasella, A, Air, G.M, Luo, M. | | 登録日 | 1994-09-26 | | 公開日 | 1995-02-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.
J.Mol.Biol., 245, 1995
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1IO9
 | | THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | | 分子名称: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2001-02-08 | | 公開日 | 2001-03-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
J.Inorg.Biochem., 91, 2002
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2A62
 | | Crystal structure of mouse cadherin-8 EC1-3 | | 分子名称: | CALCIUM ION, Cadherin-8 | | 著者 | Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Arkus, N, Schieren, I, Jessell, T.M, Honig, B, Price, S.R, Shapiro, L. | | 登録日 | 2005-07-01 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Type II cadherin ectodomain structures: implications for classical cadherin specificity.
Cell(Cambridge,Mass.), 124, 2006
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2X4Z
 | | Crystal Structure of the Human p21-Activated Kinase 4 in Complex with PF-03758309 | | 分子名称: | GLYCEROL, PF-3758309, SERINE/THREONINE-PROTEIN KINASE PAK 4 | | 著者 | Knighton, D.R, Deng, Y, Murray, B, Guo, C, Piraino, J, Westwick, J, Zhang, C, Lamerdin, J, Dagostino, E, Loi, C.-M, Zager, M, Kraynov, E, Christensen, J, Martinez, R, Kephart, S, Marakovits, J, Karlicek, S, Bergqvist, S, Smeal, T. | | 登録日 | 2010-02-03 | | 公開日 | 2010-05-19 | | 最終更新日 | 2019-01-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Small-Molecule P21-Activated Kinase Inhibitor Pf- 3758309 is a Potent Inhibitor of Oncogenic Signaling and Tumor Growth.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1IOT
 | | STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION | | 分子名称: | LYSOZYME C | | 著者 | Ohmura, T, Ueda, T, Ootsuka, K, Saito, M, Imoto, T. | | 登録日 | 2001-03-28 | | 公開日 | 2001-04-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Stabilization of hen egg white lysozyme by a cavity-filling mutation.
Protein Sci., 10, 2001
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1YCB
 | | DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R. | | 登録日 | 1993-08-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
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2WOU
 | | ALK5 IN COMPLEX WITH 4-((4-((2,6-dimethyl-3-pyridyl)oxy)-2-pyridyl) amino)benzenesulfonamide | | 分子名称: | 1,2-ETHANEDIOL, 4-({4-[(2,6-DIMETHYLPYRIDIN-3-YL)OXY]PYRIDIN-2-YL}AMINO)BENZENESULFONAMIDE, TGF-BETA RECEPTOR TYPE-1 | | 著者 | Debreczeni, J.E, Norman, R.A, Goldberg, F.W, Ward, R.A, Finlay, R, Powell, S.J, Roberts, N.J, Dishington, A.P, Gingell, H.J, Wickson, K.F, Roberts, A.L. | | 登録日 | 2009-07-28 | | 公開日 | 2009-09-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Rapid Generation of a High Quality Lead for Transforming Growth Factor-Beta (Tgf-Beta) Type I Receptor (Alk5).
J.Med.Chem., 52, 2009
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1YCA
 | | DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY | | 分子名称: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R. | | 登録日 | 1993-08-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
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2AFP
 | | THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY | | 分子名称: | PROTEIN (SEA RAVEN TYPE II ANTIFREEZE PROTEIN) | | 著者 | Gronwald, W, Loewen, M.C, Lix, B, Daugulis, A.J, Sonnichsen, F.D, Davies, P.L, Sykes, B.D. | | 登録日 | 1998-12-14 | | 公開日 | 1998-12-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of type II antifreeze protein reveals a new member of the lectin family.
Biochemistry, 37, 1998
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1LH7
 | | X-RAY STRUCTURAL INVESTIGATION OF LEGHEMOGLOBIN. VI. STRUCTURE OF ACETATE-FERRILEGHEMOGLOBIN AT A RESOLUTION OF 2.0 ANGSTROMS (RUSSIAN) | | 分子名称: | LEGHEMOGLOBIN (NITROSOBENZENE), NITROSOBENZENE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Vainshtein, B.K, Harutyunyan, E.H, Kuranova, I.P, Borisov, V.V, Sosfenov, N.I, Pavlovsky, A.G, Grebenko, A.I, Konareva, N.V. | | 登録日 | 1982-04-23 | | 公開日 | 1983-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-Ray Structural Investigation of Leghemoglobin. Vi. Structure of Acetate-Ferrileghemoglobin at a Resolution of 2.0 Angstroms (Russian)
Kristallografiya, 25, 1980
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1YDR
 | | STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H7 PROTEIN KINASE INHIBITOR 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE | | 分子名称: | 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, C-AMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR PEPTIDE | | 著者 | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | | 登録日 | 1996-07-24 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
J.Biol.Chem., 271, 1996
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1TGN
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1YDT
 | | STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H89 PROTEIN KINASE INHIBITOR N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE | | 分子名称: | C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE | | 著者 | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | | 登録日 | 1996-07-24 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
J.Biol.Chem., 271, 1996
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2EN6
 | | Solution structure of the C2H2 type zinc finger (region 887-919) of human Zinc finger protein 268 | | 分子名称: | ZINC ION, Zinc finger protein 268 | | 著者 | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-28 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C2H2 type zinc finger (region 887-919) of human Zinc finger protein 268
To be Published
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1YDS
 | | Structure of CAMP-dependent protein kinase, alpha-catalytic subunit in complex with H8 protein kinase inhibitor [N-(2-methylamino)ethyl]-5-isoquinolinesulfonamide | | 分子名称: | C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE | | 著者 | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | | 登録日 | 1996-07-24 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
J.Biol.Chem., 271, 1996
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