PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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3FI2	Crystal structure of JNK3 with amino-pyrazole inhibitor, SR-3451 分子名称: 1,2-ETHANEDIOL, 3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}-N-(3,4,5-trimethoxyphenyl)benzamide, Mitogen-activated protein kinase 10 著者 Habel, J.E. 登録日 2008-12-10 公開日 2009-03-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J.Biol.Chem., 284, 2009
2A5X	Crystal Structure of a Cross-linked Actin Dimer 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Actin, alpha skeletal muscle, ... 著者 Kudryashov, D.S, Sawaya, M.R, Adisetiyo, H, Norcross, T, Hegyi, G, Reisler, E, Yeates, T.O. 登録日 2005-07-01 公開日 2005-08-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin Proc.Natl.Acad.Sci.Usa, 102, 2005
2A9O	Crystal structures of an activated YycF homologue, the essential response regulator from S.pneumoniae in complex with BeF3 and the effect of pH on BeF3 binding, possible phosphate in the active site 分子名称: BERYLLIUM TRIFLUORIDE ION, MANGANESE (II) ION, Response regulator 著者 Riboldi-Tunnicliffe, A, Isaacs, N.W, Mitchell, T.J. 登録日 2005-07-12 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structures of an activated YycF homologue, the essential response regulator from S.pneumoniae in complex with BeF3 and the effect of pH on BeF3 binding, possible phosphate in the active site. TO BE PUBLISHED
1TIO	HIGH PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE 分子名称: BENZAMIDINE, CALCIUM ION, CYCLOHEXANE, ... 著者 Huang, Q, Zhu, G, Wang, Z, Tang, Q. 登録日 1998-09-17 公開日 1998-09-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane. Biochim.Biophys.Acta, 1429, 1998
2AAS	HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF RIBONUCLEASE A IN SOLUTION BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY 分子名称: RIBONUCLEASE A 著者 Santoro, J, Gonzalez, C, Bruix, M, Neira, J.L, Nieto, J.L, Herranz, J, Rico, M. 登録日 1992-11-20 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 High-resolution three-dimensional structure of ribonuclease A in solution by nuclear magnetic resonance spectroscopy. J.Mol.Biol., 229, 1993
1HVJ	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-3-HYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
3EZV	CDK-2 with indazole inhibitor 9 bound at its active site 分子名称: 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 著者 Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. 登録日 2008-10-23 公開日 2009-02-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Bioorg.Med.Chem.Lett., 19, 2009
1HVI	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
2AC5	Structure of human Mnk2 Kinase Domain mutant D228G 分子名称: MAP kinase-interacting serine/threonine kinase 2, ZINC ION 著者 Jauch, R, Wahl, M.C, Jakel, S, Schreiter, K, Aicher, B, Jackle, H. 登録日 2005-07-18 公開日 2005-10-04 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site. Structure, 13, 2005
1HSH	CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES 分子名称: HIV-II PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE 著者 Chen, Z. 登録日 1995-03-31 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases. J.Biol.Chem., 269, 1994
1HUR	HUMAN ADP-RIBOSYLATION FACTOR 1 COMPLEXED WITH GDP, FULL LENGTH NON-MYRISTOYLATED 分子名称: GUANOSINE-5'-DIPHOSPHATE, HUMAN ADP-RIBOSYLATION FACTOR 1, MAGNESIUM ION 著者 Amor, J.C, Harrison, D.H, Kahn, R.A, Ringe, D. 登録日 1995-04-19 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the human ADP-ribosylation factor 1 complexed with GDP. Nature, 372, 1994
1HVK	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
1HPX	HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR KNI-272 分子名称: (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide, HIV-1 PROTEASE 著者 Bhat, T.N, Erickson, J.W. 登録日 1995-05-18 公開日 1996-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine. Structure, 3, 1995
1HSY	ORIGIN OF THE PH-DEPENDENT SPECTROSCOPIC PROPERTIES OF PENTACOORDINATE METMYOGLOBIN VARIANTS 分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Maurus, R, Brayer, G.D. 登録日 1994-12-12 公開日 1995-02-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Origin of the pH-dependent spectroscopic properties of pentacoordinate metmyoglobin variants. Biochemistry, 34, 1995
1HVS	STRUCTURAL BASIS OF DRUG RESISTANCE FOR THE V82A MUTANT OF HIV-1 PROTEASE: BACKBONE FLEXIBILITY AND SUBSITE REPACKING 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Baldwin, E.T, Bhat, T.N, Liu, B, Pattabiraman, N, Erickson, J.W. 登録日 1994-11-17 公開日 1995-02-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase. Nat.Struct.Biol., 2, 1995
1HVL	INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2R,3R)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Hosur, M.V, Baldwin, E.T, Erickson, J.W. 登録日 1994-01-26 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease J.Am.Chem.Soc., 116, 1994
1XCH	MYOGLOBIN (HORSE HEART) MUTANT WITH LEU 104 REPLACED BY ASN (L104N) 分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Maurus, R, Brayer, G.D. 登録日 1997-06-06 公開日 1997-09-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket. Biochim.Biophys.Acta, 1341, 1997
2AC3	Structure of human Mnk2 Kinase Domain 分子名称: MAP kinase-interacting serine/threonine kinase 2, ZINC ION 著者 Jauch, R, Wahl, M.C, Netter, C, Jakel, S, Schreiter, K, Aicher, B, Jackle, H. 登録日 2005-07-18 公開日 2005-10-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site. Structure, 13, 2005
1XGL	HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES 分子名称: INSULIN 著者 Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. 登録日 1996-10-10 公開日 1997-04-01 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Structure of a protein in a kinetic trap. Nat.Struct.Biol., 2, 1995
1HYL	THE 1.8 A STRUCTURE OF COLLAGENASE FROM HYPODERMA LINEATUM 分子名称: HYPODERMA LINEATUM COLLAGENASE 著者 Broutin, I, Arnoux, B, Riche, C, Lecroisey, A, Keil, B, Pascard, C, Ducruix, A. 登録日 1995-05-02 公開日 1995-07-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family. Acta Crystallogr.,Sect.D, 52, 1996
1HUP	HUMAN MANNOSE BINDING PROTEIN CARBOHYDRATE RECOGNITION DOMAIN TRIMERIZES THROUGH A TRIPLE ALPHA-HELICAL COILED-COIL 分子名称: CALCIUM ION, MANNOSE-BINDING PROTEIN, SULFATE ION 著者 Sheriff, S. 登録日 1994-09-21 公開日 1995-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple alpha-helical coiled-coil. Nat.Struct.Biol., 1, 1994
1XEK	THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION 分子名称: LYSOZYME 著者 Nagendra, H.G, Sukumar, N, Vijayan, M. 登録日 1998-01-16 公開日 1998-04-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Role of water in plasticity, stability, and action of proteins: the crystal structures of lysozyme at very low levels of hydration. Proteins, 32, 1998
1HNE	Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-angstroms resolution 分子名称: HUMAN LEUCOCYTE ELASTASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALA CHLOROMETHYL KETONE INHIBITOR 著者 Navia, M.A, Mckeever, B.M, Springer, J.P, Lin, T.-Y, Williams, H.R, Fluder, E.M, Dorn, C.P, Hoogsteen, K. 登録日 1989-04-10 公開日 1989-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution. Proc.Natl.Acad.Sci.USA, 86, 1989
1HNL	CRYSTAL STRUCTURE OF A GLUTATHIONYLATED HUMAN LYSOZYME: A FOLDING INTERMEDIATE MIMIC IN THE FORMATION OF A DISULFIDE BOND 分子名称: GLUTATHIONE, HUMAN LYSOZYME 著者 Inaka, K, Matsushima, M, Miki, K. 登録日 1994-12-22 公開日 1995-02-14 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a glutathionylated human lysozyme: a folding intermediate mimic in the formation of a disulfide bond. Acta Crystallogr.,Sect.D, 51, 1995
1XEI	THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION 分子名称: LYSOZYME 著者 Nagendra, H.G, Sukumar, N, Vijayan, M. 登録日 1998-01-16 公開日 1998-04-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of water in plasticity, stability, and action of proteins: the crystal structures of lysozyme at very low levels of hydration. Proteins, 32, 1998

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