PDB: 1359 件ウェブページステータス検索Chemie searchBIRD

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4G3X	Crystal Structure of Q61L H-Ras-GppNHp bound to the RBD of Raf Kinase 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Fetics, S.K, Kearney, B.M, Buhrman, G, Mattos, C. 登録日 2012-07-15 公開日 2013-07-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD. Structure, 23, 2015
4FMB	VirA-Rab1 complex structure 分子名称: ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Shao, F, Zhu, Y. 登録日 2012-06-16 公開日 2012-09-05 最終更新日 2012-10-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
4HAW	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB4	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAZ	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HDQ	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail 分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ... 著者 Gingras, A.R. 登録日 2012-10-02 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail. J.Biol.Chem., 288, 2013
4HAY	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB3	Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HDO	Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase 分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ... 著者 Gingras, A.R. 登録日 2012-10-02 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail. J.Biol.Chem., 288, 2013
4FMC	EspG-Rab1 complex 分子名称: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Shao, F, Zhu, Y. 登録日 2012-06-16 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4GPT	Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-08-21 公開日 2012-09-05 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Leukemia, 27, 2013
4HB0	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAX	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAV	Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 分子名称: Anguinomycin A, bound form, CHLORIDE ION, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB2	Crystal structure of CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAU	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
7G84	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1102357527 分子名称: DIMETHYL SULFOXIDE, FORMIC ACID, N-[(3R)-6-oxopiperidin-3-yl]-1,3-thiazole-4-carboxamide, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.811 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published
7G86	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1137725943 分子名称: DIMETHYL SULFOXIDE, FORMIC ACID, N-[(1H-indol-4-yl)methyl]ethanamine, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published
7G8H	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1198180782 分子名称: 5-methoxy-1H-pyrrolo[3,2-b]pyridine, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published
7G8I	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1198316457 分子名称: 4,4-difluorocyclohexane-1-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.468 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published
7JHP	Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Cookis, T, Mattos, C. 登録日 2020-07-21 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.766 Å) 主引用文献 Crystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation. Biomolecules, 11, 2021
7G8K	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1217131798 分子名称: (3M)-3-(2-methyl-1H-imidazol-1-yl)pyridine, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.491 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published
7G90	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1509195674 分子名称: 4-[(3S)-piperidin-3-yl]-1H-indole, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.911 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published
7G93	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1565771450 分子名称: DIMETHYL SULFOXIDE, FORMIC ACID, N-(8-methyl-1,2,3,4-tetrahydroquinolin-5-yl)acetamide, ... 著者 Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-06-22 公開日 2023-07-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.693 Å) 主引用文献 ARHGEF2 PanDDA analysis group deposition To Be Published

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