8GHF
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![BU of 8ghf by Molmil](/molmil-images/mine/8ghf) | cryo-EM structure of hSlo1 in plasma membrane vesicles | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ... | 著者 | Tao, X, Zhao, C, MacKinnon, R. | 登録日 | 2023-03-10 | 公開日 | 2023-05-10 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Membrane protein isolation and structure determination in cell-derived membrane vesicles. Proc.Natl.Acad.Sci.USA, 120, 2023
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5H7H
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![BU of 5h7h by Molmil](/molmil-images/mine/5h7h) | Crystal structure of the BCL6 BTB domain in complex with F1324(10-13) | 分子名称: | 1,2-ETHANEDIOL, B-cell lymphoma 6 protein, F1324 peptide residues 10-13 | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2016-11-18 | 公開日 | 2016-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem. Biophys. Res. Commun., 482, 2017
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5H7G
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![BU of 5h7g by Molmil](/molmil-images/mine/5h7g) | Crystal structure of the BCL6 BTB domain in complex with F1324 | 分子名称: | B-cell lymphoma 6 protein, F1324 peptide, SULFATE ION | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2016-11-18 | 公開日 | 2016-12-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem. Biophys. Res. Commun., 482, 2017
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5H8O
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![BU of 5h8o by Molmil](/molmil-images/mine/5h8o) | Crystal structure of an ASC-binding nanobody in complex with the CARD domain of ASC | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, VHH nanobody | 著者 | Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L. | 登録日 | 2015-12-23 | 公開日 | 2016-04-06 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (4.206 Å) | 主引用文献 | A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. J.Exp.Med., 213, 2016
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5H8D
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![BU of 5h8d by Molmil](/molmil-images/mine/5h8d) | Crystal structure of an ASC binding nanobody | 分子名称: | VHH nanobody | 著者 | Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L. | 登録日 | 2015-12-23 | 公開日 | 2016-04-06 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. J.Exp.Med., 213, 2016
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5AB6
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![BU of 5ab6 by Molmil](/molmil-images/mine/5ab6) | |
6EI3
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![BU of 6ei3 by Molmil](/molmil-images/mine/6ei3) | Crystal structure of auto inhibited POT family peptide transporter | 分子名称: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, Proton-dependent oligopeptide transporter family protein | 著者 | Newstead, S, Brinth, A, Vogeley, L, Caffrey, M. | 登録日 | 2017-09-17 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Proton movement and coupling in the POT family of peptide transporters. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6F62
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![BU of 6f62 by Molmil](/molmil-images/mine/6f62) | |
6V1D
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![BU of 6v1d by Molmil](/molmil-images/mine/6v1d) | Crystal structure of human trefoil factor 1 | 分子名称: | Trefoil factor 1 | 著者 | Jarva, M.A, Lingford, J.P, John, A, Scott, N.E, Goddard-Borger, E.D. | 登録日 | 2019-11-20 | 公開日 | 2019-12-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Trefoil factors share a lectin activity that defines their role in mucus. Nat Commun, 11, 2020
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6F64
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![BU of 6f64 by Molmil](/molmil-images/mine/6f64) | Crystal structure of the SYCP1 C-terminal back-to-back assembly | 分子名称: | ACETATE ION, Synaptonemal complex protein 1 | 著者 | Dunce, J.M, Millan, C, Uson, I, Davies, O.R. | 登録日 | 2017-12-04 | 公開日 | 2018-06-06 | 最終更新日 | 2020-04-22 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nat. Struct. Mol. Biol., 25, 2018
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6GV1
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![BU of 6gv1 by Molmil](/molmil-images/mine/6gv1) | Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment | 分子名称: | Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, ... | 著者 | Nagarathinam, K, Parthier, C, Stubbs, M.T, Tanabe, M. | 登録日 | 2018-06-20 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism. Nat Commun, 9, 2018
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7YSJ
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![BU of 7ysj by Molmil](/molmil-images/mine/7ysj) | |
5AB7
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![BU of 5ab7 by Molmil](/molmil-images/mine/5ab7) | |
5AB5
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![BU of 5ab5 by Molmil](/molmil-images/mine/5ab5) | |
6F5X
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6K2Z
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![BU of 6k2z by Molmil](/molmil-images/mine/6k2z) | Human Galectin-14 with lactose | 分子名称: | Placental protein 13-like, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Su, J. | 登録日 | 2019-05-15 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-function studies of galectin-14, an important effector molecule in embryology. Febs J., 288, 2021
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6K2Y
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![BU of 6k2y by Molmil](/molmil-images/mine/6k2y) | Human Galectin-14 | 分子名称: | Placental protein 13-like | 著者 | Su, J. | 登録日 | 2019-05-15 | 公開日 | 2020-06-17 | 最終更新日 | 2021-03-10 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structure-function studies of galectin-14, an important effector molecule in embryology. Febs J., 288, 2021
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2LKW
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2P28
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![BU of 2p28 by Molmil](/molmil-images/mine/2p28) | Structure of the PHE2 and PHE3 fragments of the integrin beta2 subunit | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2 | 著者 | Shi, M, Foo, S.Y, Tan, S.M, Mitchell, E.P, Law, S.K.A, Lescar, J. | 登録日 | 2007-03-07 | 公開日 | 2007-08-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins J.Biol.Chem., 282, 2007
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8F1D
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![BU of 8f1d by Molmil](/molmil-images/mine/8f1d) | Voltage-gated potassium channel Kv3.1 apo | 分子名称: | CHOLESTEROL, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1, ... | 著者 | Chen, Y, Ishchenko, A. | 登録日 | 2022-11-04 | 公開日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1C
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![BU of 8f1c by Molmil](/molmil-images/mine/8f1c) | Voltage-gated potassium channel Kv3.1 with novel positive modulator (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one (compound 4) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one, POTASSIUM ION, ... | 著者 | Chen, Y, Ishchenko, A. | 登録日 | 2022-11-04 | 公開日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc.Natl.Acad.Sci.USA, 120, 2023
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6LSR
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![BU of 6lsr by Molmil](/molmil-images/mine/6lsr) | Cryo-EM structure of a pre-60S ribosomal subunit - state B | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | 登録日 | 2020-01-20 | 公開日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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6YV7
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![BU of 6yv7 by Molmil](/molmil-images/mine/6yv7) | |
2PET
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![BU of 2pet by Molmil](/molmil-images/mine/2pet) | |
2P26
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![BU of 2p26 by Molmil](/molmil-images/mine/2p26) | Structure of the PHE2 and PHE3 fragments of the integrin beta2 subunit | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2 | 著者 | Shi, M, Foo, S.Y, Tan, S.M, Mitchell, E.P, Law, S.K.A, Lescar, J. | 登録日 | 2007-03-06 | 公開日 | 2007-08-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins J.Biol.Chem., 282, 2007
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