PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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2FJU	Activated Rac1 bound to its effector phospholipase C beta 2 分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ... 著者 Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J. 登録日 2006-01-03 公開日 2006-11-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Rac1 bound to its effector phospholipase C-beta2. Nat.Struct.Mol.Biol., 13, 2006
1EBZ	HIV-1 protease in complex with the inhibitor BEA388 分子名称: HIV-1 PROTEASE, [5-(2-HYDROXY-INDAN-1-YLCARBAMOYL)-3,4-DIHYDROXY-2,5-[DIBENZYL-OXY]-PENTANOYL]-VALINYL-AMIDO-METHANE 著者 Unge, T. 登録日 2000-01-25 公開日 2002-06-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors Eur.J.Biochem., 270, 2003
2FSM	mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-B 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Livnah, O. 登録日 2006-01-23 公開日 2006-12-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365, 2007
2FST	mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Livnah, O. 登録日 2006-01-23 公開日 2006-12-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365, 2007
2R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI 分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, THYMIDINE-5'-TRIPHOSPHATE 著者 Eriksson, M, Eklund, H. 登録日 1997-07-21 公開日 1998-01-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
2LDX	CHARACTERIZATION OF THE ANTIGENIC SITES ON THE REFINED 3-ANGSTROMS RESOLUTION STRUCTURE OF MOUSE TESTICULAR LACTATE DEHYDROGENASE C4 分子名称: APO-LACTATE DEHYDROGENASE 著者 Griffith, J.P, Rossmann, M.G. 登録日 1987-11-25 公開日 1989-04-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Characterization of the antigenic sites on the refined 3-A resolution structure of mouse testicular lactate dehydrogenase C4. J.Biol.Chem., 262, 1987
2FSO	mitogen activated protein kinase p38alpha (D176A) activating mutant 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Livnah, O. 登録日 2006-01-23 公開日 2006-12-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365, 2007
2FSL	mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Livnah, O. 登録日 2006-01-23 公開日 2006-12-05 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation J.Mol.Biol., 365, 2007
6XZ7	E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet). 分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... 著者 Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. 登録日 2020-02-03 公開日 2020-07-22 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome. Rna, 26, 2020
8A06	Flavobacterium infecting lipid-containing phage FLiP penton protein 分子名称: Penton protein P12 著者 Rissanen, I, Huiskonen, J.T. 登録日 2022-05-26 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
6X9I	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
6X9K	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3685032A 分子名称: (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl}-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
6X9J	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3830052 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
6XLZ	Structure of NHP D11A.F2 Fab in complex with 16055 V2b peptide 分子名称: (R,R)-2,3-BUTANEDIOL, Envelope glycoprotein gp160, NHP_D11A.F2_Fab_Heavy_chain, ... 著者 Aljedani, S, Rodarte, J, Liban, T, Pancera, M. 登録日 2020-06-29 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
5YKX	The crystal structure of Macrobrachium rosenbergii nodavirus P-domain with Cd ion 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, Capsid protein, ... 著者 Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. 登録日 2017-10-16 公開日 2018-10-24 最終更新日 2019-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
1PK0	Crystal Structure of the EF3-CaM complexed with PMEApp 分子名称: (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE, CALCIUM ION, Calmodulin, ... 著者 Shen, Y, Tang, W.J. 登録日 2003-06-04 公開日 2004-02-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. Proc.Natl.Acad.Sci.USA, 101, 2004
5YKV	The crystal structure of Macrobrachium rosenbergii nodavirus P-domain 分子名称: Capsid protein 著者 Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. 登録日 2017-10-16 公開日 2018-10-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
5YKU	The crystal structure of Macrobrachium rosenbergii nodavirus P-domain with Zn ions 分子名称: Capsid protein, ZINC ION 著者 Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. 登録日 2017-10-16 公開日 2018-10-24 最終更新日 2019-03-13 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
7WWW	Crystal Structure of Moonlighting GAPDH protein of Lactobacillus gasseri 分子名称: 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Jeng, W.Y, Chen, P.C, Wang, J.Y. 登録日 2022-02-14 公開日 2023-02-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Moonlighting GAPDH protein of Lactobacillus gasseri attenuates allergic asthma via immunometabolism change in macrophages To Be Published
1NHB	Specificity of ligand binding in a buried non-polar cavity of t4 lysozyme: linkage of dynamics and structural plasticity 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PHENYLETHANE, ... 著者 Morton, A, Matthews, B.W. 登録日 1995-02-24 公開日 1995-07-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995
8ALO	Heterodimer formation of sensory domains of Vibrio cholerae regulators ToxR and ToxS 分子名称: Cholera toxin transcriptional activator, Transmembrane regulatory protein ToxS 著者 Gubensaek, N, Sagmeister, T, Pavkov-Keller, T, Zangger, K, Buhlheller, C, Wagner, G.E. 登録日 2022-08-01 公開日 2023-09-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Vibrio cholerae's ToxRS bile sensing system. Elife, 12, 2023
5WLG	Crystal Structure of H-2Db with the GAP501 peptide (SQL) 分子名称: Beta-2-microglobulin, CHLORIDE ION, GAP50 peptide, ... 著者 Gras, S, Farenc, C, Josephs, T, Rossjohn, J. 登録日 2017-07-26 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene. Immunity, 47, 2017
8BBH	The crystal structure of a mouse Fab fragment TL1 in complex with a human Glucose-6-phosphate isomerase peptide 293-307 分子名称: Glucose-6-phosphate isomerase, Heavy Chain of TL1 Fab fragment, Light Chain of TL1 Fab fragment 著者 Ge, C, Holmdahl, R, Li, T. 登録日 2022-10-13 公開日 2022-12-21 最終更新日 2023-07-05 実験手法 X-RAY DIFFRACTION (1.619 Å) 主引用文献 Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage. Ann Rheum Dis, 82, 2023
6Z41	NMR solution structure of the carbohydrate-binding module family 73 (CBM73) from Cellvibrio japonicus CjLPMO10A 分子名称: Carbohydrate binding protein, putative, cpb33A 著者 Madland, E, Aachmann, F.L, Courtade, G. 登録日 2020-05-22 公開日 2021-05-05 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus. J.Biol.Chem., 297, 2021
5WLI	Crystal Structure of H-2Db with the GAP501 peptide (SQL) 分子名称: Beta-2-microglobulin, GAP50 peptide, H-2 class I histocompatibility antigen, ... 著者 Gras, S, Farenc, C, Josephs, T, Rossjohn, J. 登録日 2017-07-27 公開日 2017-11-15 最終更新日 2019-05-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene. Immunity, 47, 2017

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